Protein Alignment Hil and Rassf

DIOPT Version :9

• Sequence 1: NP_611493.2
• Gene: Hil / 37328
• FlyBaseID: FBgn0050147
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: NP_651126.3
• Gene: Rassf / 42734
• FlyBaseID: FBgn0039055
• Length: 806
• Species: Drosophila melanogaster
• Alignment Length: 650
• Identity: 131/650 - (20%)
• Similarity: 223/650 - (34%)
• Gaps: 193/650 - (29%)

  Fly    11 CLRCSETVYQVDR---VGPLKDFTFFHSGCFKCVHCGTKLTLKTYFNNQHKQDDKEVYCSSHVPK 72
            |.:|.:.||..:|   :|     ..:|..|.:|..||.:|.     ..||.:.....||  |||.
  Fly     4 CHKCGKPVYFAERKQSIG-----YDWHPECLRCEECGKRLN-----PGQHAEHKSVPYC--HVPC 56

  Fly    73 SGPGHLDQTSVGIRQALNAPRTNKFVNEQIRGTRSEVDGGPLGGSRQSTPNGYGSREISSPSQND 137
            .|             ||..|        |:.|          .|:|..:...||.:....|:...
  Fly    57 YG-------------ALFGP--------QLFG----------HGTRVESHKSYGVKGAQKPTGAQ 90

  Fly   138 SDYKYGRFDASALHIAHALKQTEIQKAYNKAREKPIDFYLAREEQAHLEMKHRKEEDDLYRKFAS 202
            ::......|    |:...|      |.||:       ||    :...||::.|:..:.|..:.|.
  Fly    91 ANGPPLPRD----HLESKL------KVYNQ-------FY----DNKSLEIRSREVNNRLVLEGAL 134

  Fly   203 KRAEEDRKIQDEFQDEWERELQRLTHKFEKELATSRRSRDEANILTMRHEQQKEDLEKNMTLRRS 267
            :.....:.:....:|:.:|.|.|..:......|.:..|.|:.|       :..|.|....|....
  Fly   135 RVYWGVQGVIHLKEDDDQRILVRKRNSCRVSKAANESSSDKEN-------EASESLAPPTTTTAE 192

  Fly   268 KKKESITRKMLEHERYETAALVDRQSSEMLEL------ISAR---RSEYMQSESIFLDDE----- 318
            ..:.|....:.|...:::.:|     :|:.||      .||.   .|:...:.::..|||
  Fly   193 VDQLSTDVSLSESMTFDSCSL-----NEISELPTTPEDASANTTANSKEQTNGNVCNDDEDTTTT 252

  Fly   319 FSEGAVPVEYPLNAPIPAPPAVSKFQIYTDP--------IEFEDVD------------------- 356
            .|.|.:     :.||..:...||.    |.|        ::::|:|
  Fly   253 DSSGTL-----VEAPTASTSCVSS----TLPSKLDRLEKLDWDDIDDLLQVERRHNDKDRIYETM 308

  Fly   357 --RIAISVAQED---QKTFTDLVRQLVGRCTTDIEKARTIFRWITVKNLNAMHFDDDLRGDTPMG 416
              ::..|.:..|   .||.|:        .||..|.:.|     ...:.|....||.:   |..|
  Fly   309 PVKLPSSQSSSDSSPSKTSTE--------TTTTTESSST-----QSASTNTSSTDDFM---TATG 357

  Fly   417 LLRGIKYGTESYHVLFKRLCSYAGLH-CVVIKGYSKSAGYQPGVKFQDSRFRNSWNAVYVAGAWR 480
            .|.. ...|::...:.....|..... |       ..|..:| :.|:|  |:.|.:..||.||..
  Fly   358 SLTA-NTNTQNTTTVSTTETSLDNFETC-------DDATLKP-IDFED--FKRSVHQDYVNGANS 411

  Fly   481 FVQCNWGARHLVNAKEAPKQGR--------GKNDSLRYEYDDHYFL--TDP---------REFIY 526
            |.:.|.|.   :...:.....|        |:|.::...::..:.|  .||         |..:.
  Fly   412 FTEPNEGT---LKRNQPIDPSRIHDSLKLYGENSAMSKSFNCEHALRSIDPTLINDTMNLRSSVG 473

  Fly   527 EFYPLQEEWQLLK---RPITLREFENLPFV--RSLFFRYGLHFADEGYGAVVF--TDDTGAATVR 584
            ..:..|.::.|.|   ..:|.|: :..|:.  |.||.: |::.:..|....|:  :||...||:|
  Fly   474 SPHSAQRQYALQKSGSATVTSRD-QKKPYQQGRQLFEK-GINRSKSGPSCFVYSDSDDDDEATLR 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hil	NP_611493.2	LIM_Ltd-1	11..70	CDD:188827	16/61 (26%)
		BAR	<147..>265	CDD:299863	23/117 (20%)
		TGc	418..486	CDD:214673	15/68 (22%)
Rassf	NP_651126.3	LIM_TLP_like	4..57	CDD:188785	19/64 (30%)
		UBQ	660..744	CDD:294102
		Nore1-SARAH	762..799	CDD:293125

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900