Protein Alignment Hil and mical3a

DIOPT Version :10

• Sequence 1: NP_611493.2
• Gene: Hil / 37328
• FlyBaseID: FBgn0050147
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: XP_073785932.1
• Gene: mical3a / 402881
• ZFINID: ZDB-GENE-050126-2
• Length: 2522
• Species: Danio rerio
• Alignment Length: 519
• Identity: 98/519 - (18%)
• Similarity: 178/519 - (34%)
• Gaps: 147/519 - (28%)

  Fly     2 YRPNFYES-----TCLRCSETVYQVDRVGPLKDFTFFHSGCFKCVHCGTKLTLKTYFNNQHKQDD 61
            :|..|.::     .|..|.:.||.::|:.  .:..|||..||||.:|||.|.|.:|   ....:|
Zfish  1072 FRKEFPQNIGGSDVCFFCRKRVYVMERLS--AEGKFFHRSCFKCDYCGTTLRLSSY---AFDVED 1131

  Fly    62 KEVYCSSH--------------VPKSGPGH-------------LDQTSVGIRQALNAPR------ 93
            .:.||..|              .|.:.|.:             :|.....|.....|.|
Zfish  1132 GKFYCKPHYCYRLSGVAQRKRPAPAAAPANAKEPQVLAVSPNTVDAPGQAITTQTPAERRPSETE 1196

  Fly    94 ----TNKFVNEQIRGT--RSEVDGGPLGGSRQSTPNGYGSREISS-PSQNDSDYKYGRFDASALH 151
                |...|.::::||  |.|::...|...|:        .|:.. |.:..:::..    :|.|.
Zfish  1197 VNGVTEPSVAKRLKGTPERIELENYRLSMMRE--------EELEEVPEETLAEHNL----SSVLD 1249

  Fly   152 IAHALKQTEIQKAYNKA----REKPIDFYLA-----------REEQAHLEMKHRK----EEDDLY 197
                 |.|:|::..:.:    .|:..|...|           ...:.|.::|...    ::|.|:
Zfish  1250 -----KATDIEEGSSSSESDMEEEDEDAEAAGPSDLGGVPWKEAVELHAKLKGESDPGADDDGLH 1309

  Fly   198 ----RKFASKRAEEDRKIQDEFQDE----------WERELQ------RLTHKFEKELATSRRSRD 242
                .....:..|||.:.:||.::|          ||||||      .|.::.:..:..:|..:.
Zfish  1310 DGDGEMDEDEEEEEDEEDEDEEEEEESSEAGDYFPWERELQSGLWLENLANEEDVSVFKARNLQI 1374

  Fly   243 EANI-------LTMRHEQQKEDLEK------------NMTLRRSKKKESITRKMLEHERYETAAL 288
            :..|       :.|...|.:..||.            |..|.:.....:.:.|.:.||  ...|.
Zfish  1375 QQAIHPVDPLDIQMESHQAEGVLEMPSVSPLGSQPSLNTQLTQPTSSTAPSHKSVRHE--AVRAW 1437

  Fly   289 VDRQSSEMLELISARRSE----------YMQSESIFLDDEFSEGAVPVEYPLNAPIPAPPAVSKF 343
            :|..|.|..|......:|          .:..|.|..|.|....:..::..:..|:......|:.
Zfish  1438 LDSMSGEPCEEDDDPEAEAGSPDFEPGTEIDQEDIPSDAEAEARSRCIDEVVTLPVDNDKTESQG 1502

  Fly   344 QIYTDPIEFEDVDRIAISVAQEDQKTFTDLVRQLVGRCTTDIEKARTIFRWITVKNLNAMHFDD 407
            |::          ..|...:...::...|:|...:.:....||:...:...:.||:..|..|.:
Zfish  1503 QVF----------NTAEKTSANPRELIVDVVLSPIQKPALPIEEVHEVSPVVLVKSPGARFFPE 1556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hil	NP_611493.2	LIM_Ltd-1	11..70	CDD:188827	22/72 (31%)
		PTZ00121	<144..327	CDD:173412	46/250 (18%)
		CYK3	<342..550	CDD:444090	10/66 (15%)
mical3a	XP_073785932.1	None