DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hil and Mical2

DIOPT Version :9

Sequence 1:	NP_611493.2	Gene:	Hil / 37328	FlyBaseID:	FBgn0050147	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	XP_038941120.1	Gene:	Mical2 / 365352	RGDID:	1311773	Length:	1103	Species:	Rattus norvegicus

Alignment Length:	144	Identity:	36/144 - (25%)
Similarity:	55/144 - (38%)	Gaps:	26/144 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 TCLRCSETVYQVDRVGPLKDFTFFHSGCFKCVHCGTKLTLKTYFNNQHKQDDKEVYCSSHVPKSG 74
            ||..|.:.||.::|:.  .:..|||..||:|..|...|.:..|   ....|:.:.||..|.
  Rat   980 TCYFCKKRVYVMERLS--AEGHFFHRECFRCSVCAAILRVAAY---AFDCDEGKFYCKLHF---- 1035

  Fly    75 PGHLDQTSVGIRQALNAPRTNKFVNEQIRGTRSEVDGGPLGGSRQSTP--NGYGSREISSPSQND 137
             .|...:|   :|.......|:...|:  ||..|.:     .:|:..|  :......||:|..:.
  Rat  1036 -AHCKTSS---KQRKRRAELNQQREEE--GTWPEQE-----AARRDVPAESSCAVAAISTPEGSP 1089

  Fly   138 SDYKYGRFDASALH 151
            .    .||....||
  Rat  1090 P----VRFSLPVLH 1099

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hil	NP_611493.2	LIM_Ltd-1	11..70	CDD:188827	17/58 (29%)
		BAR	<147..>265	CDD:299863	2/5 (40%)
		TGc	418..486	CDD:214673
Mical2	XP_038941120.1	FAD_binding_3	87..>274	CDD:396193
		CH_MICAL2	514..623	CDD:409099
		LIM_Mical	981..1035	CDD:188823	17/58 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910