Protein Alignment Hil and cyk3

DIOPT Version :9

• Sequence 1: NP_611493.2
• Gene: Hil / 37328
• FlyBaseID: FBgn0050147
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: NP_593561.1
• Gene: cyk3 / 2542740
• PomBaseID: SPAC9G1.06c
• Length: 886
• Species: Schizosaccharomyces pombe
• Alignment Length: 612
• Identity: 125/612 - (20%)
• Similarity: 224/612 - (36%)
• Gaps: 144/612 - (23%)

  Fly    45 TKLTLKTYFNNQHKQDDKEVYCSSHVPKSGPGHLDQTSVGIRQALNA------PRTNKFVNEQIR 103
            |.|.:.:.::|....|.:  ..:..:.:|.|..|......:.|:|||      .|.|..:....:
pombe   158 TNLDVSSRWDNTADNDSQ--IDAQDLSRSTPSPLRSAMENVLQSLNAMGKKSFSRANSPLLRLTK 220

  Fly   104 GT----------------------RSEVDGGPLGGSRQSTPNGYG------SREIS-SPSQ---- 135
            .|                      ||::|......|:..|....|      ||:|| .||.
pombe   221 STTTSKETDFIPVPPAHGSTSMTSRSKLDDSTDNSSKPRTSLQPGESPMKSSRDISRKPSMASSV 285

  Fly   136 -NDSDY--KYGRFDASALHIAHALKQ----TEIQ-------KAYNKAREKPIDFYLAREEQAHLE 186
             :.|||  ::.||.::...|...:..    |:::       |...:..|:|......|:....|:
pombe   286 LSPSDYFPQHRRFQSAPAPIPRPVSTLIPLTQVRTTASNVIKPRPQTTERPSTAQSFRKGGGFLK 350

  Fly   187 MKHRKEEDDLYRKFASKRAEEDRKIQDEFQDEWERELQRLTHKFEKELATSRRSRDEANILTMRH 251
            ...:|    |.|:.:|||               :..||.............::....|:..|::
pombe   351 KTFKK----LLRRGSSKR---------------KPSLQPTPPVSYPAHNVPQKGVRPASPHTLK- 395

  Fly   252 EQQKEDLEKNMTLRRSK---KKESITRKMLEHERYETAALVDRQSSEMLELISARRSEYMQSESI 313
             ..|:||::..|..:::   |:|.|..| |....||..       .::.|.|.          ::
pombe   396 -SVKDDLKRTKTYTKAEFAAKREEIFNK-LSMPVYEPL-------KDLSECIG----------NV 441

  Fly   314 FLDDEFSEGAVPVEYPLNAPIPAPPAVSKFQIYTDPIEFEDVDR-IAISVAQEDQKTFTDLVRQ- 376
            ..|.|      ||::.:...|             ..:.|..:|: |...:.|..|.:...|.:.
pombe   442 LADGE------PVQFSVGTNI-------------HNMNFSAIDKQIRSIIPQRVQVSPAVLAKNY 487

  Fly   377 LVGRCTTDIEKARTIFRWIT--VKNLNAMHFDDDLRGDTPMGLLRGIKYGTE-SYHVLFKRLCSY 438
            |....||.:.:.|.:|.:|:  :...|....:|:||..|.: :..|  .||. ...:|.|.:...
pombe   488 LAPGQTTALAQMRAVFIYISERITFTNQTLDNDELRTSTQV-ISEG--QGTPFEVALLVKEMLQA 549

  Fly   439 AGLHCVVIKGYSKSAGYQPGVKF--QDSRFRNSWNAVYVAGAWRFVQCNWGA-RHLVNAKEAPKQ 500
            ..|.|.||:||.||    |...:  :|....::||.|......|.:..::.: .|       |:|
pombe   550 LDLWCEVIEGYLKS----PDDIYYTRDININHAWNVVTFDNEVRLIDASFASPTH-------PQQ 603

  Fly   501 GRGKNDSLRYEYDDHYFLTDPREFIYEFYPLQEEWQLLKRPITLREFENLPFVRSLFFRYGLHFA 565
            ....:.|     :|.|||..|.|.|:...|...:.|.:...:::.....||:|.|::|..||...
pombe   604 ALKSSSS-----NDFYFLMKPNECIFTHVPENPDQQFIMPDLSMPIVMALPWVSSVYFTLGLKLR 663

  Fly   566 DEGYGAVVFTDDTGAATVRIAMPTDMQ 592
             :...:::..:|.....:....|.|::
pombe   664 -KFNTSILHLNDLEVLQIEFLAPKDIE 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hil	NP_611493.2	LIM_Ltd-1	11..70	CDD:188827	4/24 (17%)
		BAR	<147..>265	CDD:299863	21/128 (16%)
		TGc	418..486	CDD:214673	19/70 (27%)
cyk3	NP_593561.1	SH3_Cyk3p-like	10..62	CDD:212822
		CYK3	25..883	CDD:227604	125/612 (20%)
		TGc	528..595	CDD:214673	19/73 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5279
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3261
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.930