Protein Alignment Hil and Hil

DIOPT Version :10

• Sequence 1: NP_611493.2
• Gene: Hil / 37328
• FlyBaseID: FBgn0050147
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: XP_061498570.1
• Gene: Hil / 1275845
• VectorBaseID: AGAMI1_014462
• Length: 814
• Species: Anopheles gambiae
• Alignment Length: 827
• Identity: 702/827 - (84%)
• Similarity: 755/827 - (91%)
• Gaps: 22/827 - (2%)

  Fly     1 MYRPNFYESTCLRCSETVYQVDRVGPLKDFTFFHSGCFKCVHCGTKLTLKTYFNNQHKQDDKEVY 65
            ||||||||||||||||.|||||||||||||||||||||||..||||||||||:||||.|||||||
Mosquito     1 MYRPNFYESTCLRCSEIVYQVDRVGPLKDFTFFHSGCFKCKRCGTKLTLKTYYNNQHNQDDKEVY 65

  Fly    66 CSSHVPKSGPGHLDQTSVGIRQALNAPRTNKFVNEQIRGTRSE-VDGGPLGGSRQSTPNGY--GS 127
            |.||||||||||.||||||||||||.|::..:|||||||.|:: :|    |..|..|||||  |.
Mosquito    66 CCSHVPKSGPGHFDQTSVGIRQALNVPKSTNYVNEQIRGHRNDSID----GQQRLGTPNGYNNGG 126

  Fly   128 REISSPSQNDSDYKYGRFDASALHIAHALKQTEIQKAYNKAREKPIDFYLAREEQAHLEMKHRKE 192
            ||.::|.|||.|||||||||||||||||||||||||||:|.||||||:||||:|||.||||||||
Mosquito   127 REGNTPPQNDPDYKYGRFDASALHIAHALKQTEIQKAYDKPREKPIDYYLARDEQAKLEMKHRKE 191

  Fly   193 EDDLYRKFASKRAEEDRKIQDEFQDEWERELQRLTHKFEKELATSRRSRDEANILTMRHEQQKED 257
            |||||||||.||.||||::|.|.|||||||||||.|||||||.||||||::.||||::|||||||
Mosquito   192 EDDLYRKFARKREEEDRRMQSEIQDEWERELQRLAHKFEKELTTSRRSREDQNILTLKHEQQKED 256

  Fly   258 LEKNMTLRRSKKKESITRKMLEHERYETAALVDRQSSEMLELISARRSEYMQSESIFLDDEFSEG 322
            ||||||:|::|||||:|||:|||||.||||||||||||||||||.|||||||||||||||:.:|.
Mosquito   257 LEKNMTIRKTKKKESLTRKLLEHERSETAALVDRQSSEMLELISVRRSEYMQSESIFLDDDINET 321

  Fly   323 AVPVEYPLNAPIPAPPAVSKFQIYTDPIEFEDVDRIAISVAQEDQKTFTDLVRQLVGRCTTDIEK 387
            .|.:||||.||.|||||:||||:|.||:||:|||:|||:|||||||||||||||||||||:||||
Mosquito   322 VVAMEYPLVAPKPAPPALSKFQVYNDPVEFQDVDQIAITVAQEDQKTFTDLVRQLVGRCTSDIEK 386

  Fly   388 ARTIFRWITVKNLNAMHFDDDLRGDTPMGLLRGIKYGTESYHVLFKRLCSYAGLHCVVIKGYSKS 452
            ||||||||||||||.|.|||:||||||||||||||||||||||||||||||||||||||||||||
Mosquito   387 ARTIFRWITVKNLNTMTFDDNLRGDTPMGLLRGIKYGTESYHVLFKRLCSYAGLHCVVIKGYSKS 451

  Fly   453 AGYQPGVKFQD------SRFRNSWNAVYVAGAWRFVQCNWGARHLVNAKEAPKQGRGKNDSLRYE 511
            |||||||||||      ||||||||||||||||||||||||||||||||||||.|:|||||||||
Mosquito   452 AGYQPGVKFQDSSHPKNSRFRNSWNAVYVAGAWRFVQCNWGARHLVNAKEAPKTGKGKNDSLRYE 516

  Fly   512 YDDHYFLTDPREFIYEFYPLQEEWQLLKRPITLREFENLPFVRSLFFRYGLHFADEGYGAVVFTD 576
            |||||||||||||||||:|||||||||||||||.|||||||||||||||||||||:||||||:||
Mosquito   517 YDDHYFLTDPREFIYEFFPLQEEWQLLKRPITLTEFENLPFVRSLFFRYGLHFADDGYGAVVYTD 581

  Fly   577 DTGAATVRIAMPTDMQSCLIFHYNLKFYDSDEELSYDGVSLKRFVMQSVIGNIVAFRVHAPCSGA 641
            ||||||||||||:|||.|||||||||||||||: |:||||||||||||||.|:||||||||||||
Mosquito   582 DTGAATVRIAMPSDMQGCLIFHYNLKFYDSDED-SFDGVSLKRFVMQSVISNVVAFRVHAPCSGA 645

  Fly   642 FLLDIFANAVTPQEYLTGEPMKFKSVCKFKICCEELQTVMVPLPDCASGEWGPTKATRLFGLIPI 706
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   646 FLLDIFANAVTPQEYLTGEPMKFKSVCKFKICCEELQTVMVPLPDCASGEWGPTKATRLFGLIPI 710

  Fly   707 THQDPLIFAGRSLDLQFRMSRPLTDFMATLHKNGIEEKKLAKYVTHSTLDDIVTFIINFPEEGQY 771
            ||.:|||||||:::||||||||||||||||||||||||||:|||..:.|||::||.|:|||||||
Mosquito   711 THPEPLIFAGRAIELQFRMSRPLTDFMATLHKNGIEEKKLSKYVQQAILDDMITFNISFPEEGQY 775

  Fly   772 GLDIYTRELGGPQHHHHHNNNNSSSSSGEKHLLTHCCKYLINSSKRN 818
            ||||||||:|...|     |||||:   |||||||||||||||||||
Mosquito   776 GLDIYTREVGSVSH-----NNNSST---EKHLLTHCCKYLINSSKRN 814

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hil	NP_611493.2	LIM_Ltd-1	11..70	CDD:188827	52/58 (90%)
		PTZ00121	<144..327	CDD:173412	151/182 (83%)
		CYK3	<342..550	CDD:444090	193/213 (91%)
Hil	XP_061498570.1	None