Protein Alignment Hil and LOC101730218

DIOPT Version :10

• Sequence 1: NP_611493.2
• Gene: Hil / 37328
• FlyBaseID: FBgn0050147
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: XP_004917894.1
• Gene: LOC101730218 / 101730218
• XenbaseID: XB-GENE-29084387
• Length: 1133
• Species: Xenopus tropicalis
• Alignment Length: 729
• Identity: 164/729 - (22%)
• Similarity: 262/729 - (35%)
• Gaps: 213/729 - (29%)

  Fly   245 NILTMRHEQQKED----LEKNMTLRRSKKKESITRKMLEHERYETAALVDRQSSEMLELISARRS 305
            ::|.:.|.|.|::    .|..:.||::.|  :..:|  .|...:..:..:.|.|.:...|..:.|
 Frog    13 DLLLIVHSQDKQNGGDKSEDPVPLRQAVK--AAPKK--PHASGQIISSYESQESHVRVEIRPKTS 73

  Fly   306 EYMQSESIFLDDEFSEGAVPVEYPLNA----PIPAPPAV-------SKFQIYTDPI---EFEDVD 356
            :..     .|:...:.| .|| .|.|.    |.|.|.|.       .|..:.:.|:   .||.:|
 Frog    74 KPQ-----VLNRPTATG-TPV-LPNNGNSWDPTPQPSAKDFYAYPWDKSNLKSLPMNLKNFEKLD 131

  Fly   357 RIAISVAQEDQKTFTDLVRQLVGRCTTDIEKARTIFRWITVKNLNAMHFDDDL---------RGD 412
            ..:..|.:  ..|...||..|:....||:||.|.|:.||      ..|.:.||         .||
 Frog   132 AYSAKVGK--ASTVGQLVSSLIRMARTDLEKVRAIWTWI------CHHIEYDLDGMEDKSKRSGD 188

  Fly   413 TPMGLLRGIKYGTESYHVLFKRLCSYAGLHCVVIKGYSKSAGYQPGVKFQDSRFRNSWNAVYVAG 477
            ....||.| |...|.|..||:.:||:||:.|:.|.|:||...|..|..| .....::||||::..
 Frog   189 PNQTLLSG-KGACEGYAGLFENMCSHAGIQCLKIGGFSKGFCYTTGQTF-SGETNHAWNAVFLNK 251

  Fly   478 AWRFVQCNWGARHLVNAKEAPKQGRGKNDSLRYEYDDHYFLTDPREFIYEFYPLQEEWQLLKRPI 542
            .|..:...|||..          .....:|.::.|::.||||.|..||.|.:|..:.||||:.|:
 Frog   252 RWHLLDTTWGAGF----------ANSSTNSFKFRYNEFYFLTHPALFIEEHFPDNQNWQLLQVPL 306

  Fly   543 TLREFENLPFVRSLFFRYGL-----------------HFADEGYGAVVF------TDDTGAATV- 583
            ::::||......|.|:..||                 .|:.||:...:|      |:..|..|:
 Frog   307 SMKQFEGNLCRNSSFYNAGLTASYPETLQVETVNGKATFSIEGHSPALFSFTLNKTEKPGIMTLT 371

  Fly   584 RIAMPTDMQSCLIFHYNLKFYD---SDEELSYD-------------------------------- 613
            :..|..|:...:...:.|:.|.   :..:.|||
 Frog   372 KNGMQLDVYPTVTGRHKLELYTKPFNTVKESYDKVVEYILHCGSVDTGFRIPKELDPIVGPSWLT 436

  Fly   614 ------------------------GVSL--------------------KRFVMQSVIGNIVAFRV 634
                                    |.:|                    .|:|:|::.||.|.|::
 Frog   437 EMKGFLQHLCSDPIIYTQDGCCSVGFTLAKKAIVLATLHSDNIKPGYENRYVLQTLRGNRVEFKI 501

  Fly   635 HAPCSGAFLLDIFANAVTPQEYLTGEPMKFKSVCKFKICCEELQTVMVPLPDCASGEWGPTKATR 699
            |.|..|.:.|.|.:::         .|:.|:..|.:.:.|...:....|.|.......|||....
 Frog   502 HLPQQGYYALKIHSSS---------GPVTFECFCNYLVVCTNAEVAWSPFPRQLQNPVGPTALME 557

  Fly   700 LFGLIPITHQDPLIF-AGRSLDLQFRMSR-------------PLTD------FMATLHKNGIEEK 744
            ..||:..:.:||:|: :|....|.|.:..             ||||      .|.|...|.:|.:
 Frog   558 KKGLLQPSQRDPIIYTSGSHCSLSFTLKEGIKILTSLLFDETPLTDHGGKRLVMQTQKGNHVEIQ 622

  Fly   745 KLAKYVTHSTLDDIVTFIINFPEEGQYGLDIYTRELGGPQHHHHHNN-----NNSSSSSGEKHLL 804
                              |..|..|.|.|.|:......|....:.:|     :::.:.|.|..:|
 Frog   623 ------------------IYLPHAGPYILQIFANSKISPTSFEYVSNYLICCSSTEAGSSEGLVL 669

  Fly   805 THCCKYLINSSKRN 818
            ........|...||
 Frog   670 AQSTLNSANPVDRN 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hil	NP_611493.2	LIM_Ltd-1	11..70	CDD:188827
		PTZ00121	<144..327	CDD:173412	17/85 (20%)
		CYK3	<342..550	CDD:444090	69/219 (32%)
LOC101730218	XP_004917894.1	CYK3	<142..315	CDD:444090	63/190 (33%)