DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mgat1 and CGL1

DIOPT Version :9

Sequence 1:	NP_525117.2	Gene:	Mgat1 / 37323	FlyBaseID:	FBgn0034521	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_195537.2	Gene:	CGL1 / 829981	AraportID:	AT4G38240	Length:	444	Species:	Arabidopsis thaliana

Alignment Length:	449	Identity:	155/449 - (34%)
Similarity:	233/449 - (51%)	Gaps:	47/449 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LVTWTYATYYLLLR--QTGIHTSRHQSLQAYKLNSQARDANMQSHHLAKNVFEFVKLKYLEKQPP 75
            |:...:...|:.:|  ||       ||..|.:|:|.....|..:..: :.:.:.|.:|
plant    12 LIPAAFMFIYIQMRLFQT-------QSQYADRLSSAIESENHCTSQM-RGLIDEVSIK------- 61

  Fly    76 SVASTPQISIIAAEISAELPEQHVA----------KSATARIPTKTYLANGE-PVFPVVVFACNR 129
                  |..|:|.|......::.:.          |...|::     ...|: ||..|||.||:|
plant    62 ------QSRIVALEDMKNRQDEELVQLKDLIQTFEKKGIAKL-----TQGGQMPVAAVVVMACSR 115

  Fly   130 VS-VKKCIDNLVQYR-PSVEQFPIIVSQDCGDEPTKEAILSYGKQVTLIEQPDLSDITVLPKEKK 192
            .. :::.:.:::.|: |...::|:.:|||..|:..|...||| .|:|.::..|...: |..:..:
plant   116 ADYLERTVKSVLTYQTPVASKYPLFISQDGSDQAVKSKSLSY-NQLTYMQHLDFEPV-VTERPGE 178

  Fly   193 FKGYYKIARHYGWALNTTF-AVGFEFVIIVEDDLNVAPDFFEYFLGTHKLLKQDPSLWCVSAWND 256
            ...||||||||.|||:..| ...|..|||:|||:.:|||||:||.....|:.:|.::...|:|||
plant   179 LTAYYKIARHYKWALDQLFYKHKFSRVIILEDDMEIAPDFFDYFEAAASLMDRDKTIMAASSWND 243

  Fly   257 NGKAAVVDAAQPELLYRTDFFPGLGWMLTKDLWAELSVKWPKSFWDDWIRHPAQRKDRVCIRPEI 321
            ||:...|.  .|..|||:||||||||||.:..|.|||.||||::||||:|.....|.|..||||:
plant   244 NGQKQFVH--DPYALYRSDFFPGLGWMLKRSTWDELSPKWPKAYWDDWLRLKENHKGRQFIRPEV 306

  Fly   322 SRTRTFGKIGVSNGLFFDKYLKHIKLSEDFVQFTKINMSYLLKDNYDNTFLRRVYTYPIVTYDEL 386
            .||..||:.|.|.|.||.:||:.|||::..|.:...::.||.:.||...|...|.....:...:|
plant   307 CRTYNFGEHGSSLGQFFSQYLEPIKLNDVTVDWKAKDLGYLTEGNYTKYFSGLVRQARPIQGSDL 371

  Fly   387 RRNLIRIEGPVRIQYTTREQYKRTTKMLGLMDDFKSGVPRTAYHGIVSF-YYNKRRVHL 444
            ......|:..|||:|..:.:::|.....|:.:::|.|||||||.|:|.| ....|||.|
plant   372 VLKAQNIKDDVRIRYKDQVEFERIAGEFGIFEEWKDGVPRTAYKGVVVFRIQTTRRVFL 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mgat1	NP_525117.2	GT13_GLCNAC-TI	119..449	CDD:133007	134/330 (41%)
CGL1	NP_195537.2	GNT-I	13..443	CDD:281116	154/448 (34%)
CGL1	NP_195537.2	Glyco_tranf_2_3	107..310	CDD:290369	90/206 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	244	1.000	Domainoid score	I556
eggNOG	1	0.900	-	-		E1_KOG1413
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1804
Inparanoid	1	1.050	244	1.000	Inparanoid score	I1060
OMA	1	1.010	-	-		QHG55205
OrthoDB	1	1.010	-	-		D1324622at2759
OrthoFinder	1	1.000	-	-		FOG0004830
OrthoInspector	1	1.000	-	-		oto3875
orthoMCL	1	0.900	-	-		OOG6_104509
Panther	1	1.100	-	-	LDO	PTHR10468
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3409
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840