DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mgat1 and Mgat1

DIOPT Version :9

Sequence 1:	NP_525117.2	Gene:	Mgat1 / 37323	FlyBaseID:	FBgn0034521	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_110488.1	Gene:	Mgat1 / 81519	RGDID:	620097	Length:	447	Species:	Rattus norvegicus

Alignment Length:	414	Identity:	223/414 - (53%)
Similarity:	278/414 - (67%)	Gaps:	34/414 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 LEKQPPSVASTPQISIIAAEISAELPEQH---------------------VAKSATARIPTKTYL 113
            |...|.|:  |.::..:|.:..|||..|.                     ||..|..|:|
  Rat    43 LGDDPASL--TREVIHLAEDAEAELERQRGLLQQIKEHYSLWRQRWRVPTVAPPAWPRVP----- 100

  Fly   114 ANGEP---VFPVVVFACNRVSVKKCIDNLVQYRPSVEQFPIIVSQDCGDEPTKEAILSYGKQVTL 175
              |.|   |.|::|.||:|.:|::|:|.|:.||||.|.||||||||||.|.|.:.|.|||..||.
  Rat   101 --GTPSPAVIPILVIACDRSTVRRCLDKLLHYRPSAEHFPIIVSQDCGHEETAQVIASYGTAVTH 163

  Fly   176 IEQPDLSDITVLPKEKKFKGYYKIARHYGWALNTTF-AVGFEFVIIVEDDLNVAPDFFEYFLGTH 239
            |.|||||:|.|.|..:||:|||||||||.|||...| ...|...::|||||.|||||||||..|:
  Rat   164 IRQPDLSNIAVQPDHRKFQGYYKIARHYRWALGQIFNKFKFPAAVVVEDDLEVAPDFFEYFQATY 228

  Fly   240 KLLKQDPSLWCVSAWNDNGKAAVVDAAQPELLYRTDFFPGLGWMLTKDLWAELSVKWPKSFWDDW 304
            .|||.|||||||||||||||..:||:::|||||||||||||||:|..||||||..||||:|||||
  Rat   229 PLLKADPSLWCVSAWNDNGKEQMVDSSKPELLYRTDFFPGLGWLLLADLWAELEPKWPKAFWDDW 293

  Fly   305 IRHPAQRKDRVCIRPEISRTRTFGKIGVSNGLFFDKYLKHIKLSEDFVQFTKINMSYLLKDNYDN 369
            :|.|.|||.|.|||||||||.|||:.|||:|.|||::||.|||::.||.||::::|||.::.||.
  Rat   294 MRRPEQRKGRACIRPEISRTMTFGRKGVSHGQFFDQHLKFIKLNQQFVPFTQLDLSYLQREAYDR 358

  Fly   370 TFLRRVYTYPIVTYDELRRNLIRIEGPVRIQYTTREQYKRTTKMLGLMDDFKSGVPRTAYHGIVS 434
            .||.:||..|.:..:::|.|..:..|.||:|||:|:.:|...|.||:|||.||||||..|.|||:
  Rat   359 DFLAQVYGAPQLQVEKVRTNDRKELGEVRVQYTSRDSFKAFAKALGVMDDLKSGVPRAGYRGIVT 423

  Fly   435 FYYNKRRVHLAPNANWKGYELSWS 458
            |.:..|||||||...|.||:.||:
  Rat   424 FQFRGRRVHLAPPETWNGYDPSWN 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mgat1	NP_525117.2	GT13_GLCNAC-TI	119..449	CDD:133007	202/330 (61%)
Mgat1	NP_110488.1	Glyco_tranf_GTA_type	12..446	CDD:416254	223/414 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350929
Domainoid	1	1.000	445	1.000	Domainoid score	I511
eggNOG	1	0.900	-	-		E1_KOG1413
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1804
Inparanoid	1	1.050	446	1.000	Inparanoid score	I1579
OMA	1	1.010	-	-		QHG55205
OrthoDB	1	1.010	-	-		D1324622at2759
OrthoFinder	1	1.000	-	-		FOG0004830
OrthoInspector	1	1.000	-	-		oto97304
orthoMCL	1	0.900	-	-		OOG6_104509
Panther	1	1.100	-	-	LDO	PTHR10468
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3409
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770