DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mgat1 and MGAT1

DIOPT Version :9

Sequence 1:	NP_525117.2	Gene:	Mgat1 / 37323	FlyBaseID:	FBgn0034521	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_001108089.1	Gene:	MGAT1 / 4245	HGNCID:	7044	Length:	445	Species:	Homo sapiens

Alignment Length:	410	Identity:	221/410 - (53%)
Similarity:	279/410 - (68%)	Gaps:	24/410 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 QPPSVAS--------TPQISIIAAEISAELPEQH--------VAKSATARIPT-------KTYLA 114
            :||||::        |.::..:|.:...||..|.        ...|...|:||       :..:.
Human    36 RPPSVSALDGDPASLTREVIRLAQDAEVELERQRGLLQQIGDALSSQRGRVPTAAPPAQPRVPVT 100

  Fly   115 NGEPVFPVVVFACNRVSVKKCIDNLVQYRPSVEQFPIIVSQDCGDEPTKEAILSYGKQVTLIEQP 179
            ....|.|::|.||:|.:|::|:|.|:.||||.|.||||||||||.|.|.:||.|||..||.|.||
Human   101 PAPAVIPILVIACDRSTVRRCLDKLLHYRPSAELFPIIVSQDCGHEETAQAIASYGSAVTHIRQP 165

  Fly   180 DLSDITVLPKEKKFKGYYKIARHYGWALNTTF-AVGFEFVIIVEDDLNVAPDFFEYFLGTHKLLK 243
            |||.|.|.|..:||:|||||||||.|||...| ...|...::|||||.|||||||||..|:.|||
Human   166 DLSSIAVPPDHRKFQGYYKIARHYRWALGQVFRQFRFPAAVVVEDDLEVAPDFFEYFRATYPLLK 230

  Fly   244 QDPSLWCVSAWNDNGKAAVVDAAQPELLYRTDFFPGLGWMLTKDLWAELSVKWPKSFWDDWIRHP 308
            .|||||||||||||||..:|||::|||||||||||||||:|..:|||||..||||:|||||:|.|
Human   231 ADPSLWCVSAWNDNGKEQMVDASRPELLYRTDFFPGLGWLLLAELWAELEPKWPKAFWDDWMRRP 295

  Fly   309 AQRKDRVCIRPEISRTRTFGKIGVSNGLFFDKYLKHIKLSEDFVQFTKINMSYLLKDNYDNTFLR 373
            .||:.|.|||||||||.|||:.|||:|.|||::||.|||::.||.||::::|||.::.||..||.
Human   296 EQRQGRACIRPEISRTMTFGRKGVSHGQFFDQHLKFIKLNQQFVHFTQLDLSYLQREAYDRDFLA 360

  Fly   374 RVYTYPIVTYDELRRNLIRIEGPVRIQYTTREQYKRTTKMLGLMDDFKSGVPRTAYHGIVSFYYN 438
            |||..|.:..:::|.|..:..|.||:|||.|:.:|...|.||:|||.||||||..|.|||:|.:.
Human   361 RVYGAPQLQVEKVRTNDRKELGEVRVQYTGRDSFKAFAKALGVMDDLKSGVPRAGYRGIVTFQFR 425

  Fly   439 KRRVHLAPNANWKGYELSWS 458
            .|||||||...|:||:.||:
Human   426 GRRVHLAPPLTWEGYDPSWN 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mgat1	NP_525117.2	GT13_GLCNAC-TI	119..449	CDD:133007	203/330 (62%)
MGAT1	NP_001108089.1	GNT-I	12..444	CDD:281116	219/407 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156973
Domainoid	1	1.000	445	1.000	Domainoid score	I532
eggNOG	1	0.900	-	-		E1_KOG1413
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1804
Inparanoid	1	1.050	448	1.000	Inparanoid score	I1631
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55205
OrthoDB	1	1.010	-	-		D1324622at2759
OrthoFinder	1	1.000	-	-		FOG0004830
OrthoInspector	1	1.000	-	-		oto90185
orthoMCL	1	0.900	-	-		OOG6_104509
Panther	1	1.100	-	-	LDO	PTHR10468
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3280
SonicParanoid	1	1.000	-	-		X3409
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800