DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mgat1 and mgat1a

DIOPT Version :9

Sequence 1:	NP_525117.2	Gene:	Mgat1 / 37323	FlyBaseID:	FBgn0034521	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	XP_005157814.1	Gene:	mgat1a / 393649	ZFINID:	ZDB-GENE-040426-1515	Length:	502	Species:	Danio rerio

Alignment Length:	466	Identity:	231/466 - (49%)
Similarity:	302/466 - (64%)	Gaps:	23/466 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRTRKVLLVIG--FLVTWTYATYYLLLRQTGIHTSRHQSLQAYKLNSQARDANMQSHHLAKNVFE 63
            :|.|..|::.|  ..|.|.....::|:|       |..|...:  |:|  |...::.|.|    |
Zfish    52 LRKRSPLVICGAFIFVAWNVVLLFVLMR-------RPSSPGTF--NNQ--DKPGETEHRA----E 101

  Fly    64 FVKLKYLEKQPPSVASTPQISIIAAEISAELPEQH--VAKSATARIP--TKTYLANGEP-VFPVV 123
            ..|...:..:...||...:..:.|.:...:..:.|  |..|....||  :|:.:.:..| |.|::
Zfish   102 GGKFGNIMNEVIRVADAFEAELAAQKKILQQIQSHWSVWDSKDGVIPEKSKSEVEHTAPVVIPIL 166

  Fly   124 VFACNRVSVKKCIDNLVQYRPSVEQFPIIVSQDCGDEPTKEAILSYGKQVTLIEQPDLSDITVLP 188
            |.|||||:||:|:|.|:::|||.|..|||||||||...|.:.|.|||.|:|.|:||||||:.|.|
Zfish   167 VIACNRVTVKRCLDKLIEHRPSAELHPIIVSQDCGHRETSDVIGSYGSQLTHIKQPDLSDVAVPP 231

  Fly   189 KEKKFKGYYKIARHYGWALNTTF-AVGFEFVIIVEDDLNVAPDFFEYFLGTHKLLKQDPSLWCVS 252
            :.|||:|||||:|||.|||:..| ...:..|::|||||.|||||||||...|.:||.||:|||||
Zfish   232 QHKKFQGYYKISRHYKWALSQVFNTFSYSSVVVVEDDLEVAPDFFEYFRALHPMLKSDPTLWCVS 296

  Fly   253 AWNDNGKAAVVDAAQPELLYRTDFFPGLGWMLTKDLWAELSVKWPKSFWDDWIRHPAQRKDRVCI 317
            ||||||:...||..:..|||||||||||||||||||||||..|||.||||||:|||.|||||.||
Zfish   297 AWNDNGRDGFVDPGKASLLYRTDFFPGLGWMLTKDLWAELEPKWPASFWDDWMRHPDQRKDRSCI 361

  Fly   318 RPEISRTRTFGKIGVSNGLFFDKYLKHIKLSEDFVQFTKINMSYLLKDNYDNTFLRRVYTYPIVT 382
            |||||||.|||:.|||.|.|:||||:.|||:.:||.|||:::|||.|:.||.:|.:.||...:||
Zfish   362 RPEISRTLTFGRKGVSLGQFYDKYLRFIKLNTEFVPFTKMDLSYLEKEKYDESFEKEVYAASLVT 426

  Fly   383 YDELRRNLIRIEGPVRIQYTTREQYKRTTKMLGLMDDFKSGVPRTAYHGIVSFYYNKRRVHLAPN 447
            .::|:...:...||.|:||::.:.:|...:.||:|||.||||||..|.|.|||....:||:|||.
Zfish   427 LEDLKSGKLSGSGPFRVQYSSPDSFKSLARNLGVMDDLKSGVPRAGYRGAVSFLLRGKRVYLAPP 491

  Fly   448 ANWKGYELSWS 458
            |.|..|:.|||
Zfish   492 AGWSRYDPSWS 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mgat1	NP_525117.2	GT13_GLCNAC-TI	119..449	CDD:133007	198/330 (60%)
mgat1a	XP_005157814.1	GT13_GLCNAC-TI	162..492	CDD:133007	198/329 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592616
Domainoid	1	1.000	442	1.000	Domainoid score	I517
eggNOG	1	0.900	-	-		E1_KOG1413
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1804
Inparanoid	1	1.050	444	1.000	Inparanoid score	I1615
OMA	1	1.010	-	-		QHG55205
OrthoDB	1	1.010	-	-		D1324622at2759
OrthoFinder	1	1.000	-	-		FOG0004830
OrthoInspector	1	1.000	-	-		otm24222
orthoMCL	1	0.900	-	-		OOG6_104509
Panther	1	1.100	-	-	O	PTHR10468
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3280
SonicParanoid	1	1.000	-	-		X3409
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	16	15.840