Protein Alignment lms and Nkx1-1

DIOPT Version :10

• Sequence 1: NP_611491.2
• Gene: lms / 37322
• FlyBaseID: FBgn0034520
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_035450.1
• Gene: Nkx1-1 / 672284
• MGIID: 109346
• Length: 440
• Species: Mus musculus
• Alignment Length: 279
• Identity: 80/279 - (28%)
• Similarity: 103/279 - (36%)
• Gaps: 96/279 - (34%)

  Fly    23 PEMRSSTSFEDSVQDESG---RGGNCLGASRASSPATSSCLDDNMDDGK------SDIDLASDDG 78
            ||::.:...|:......|   ||..|.||:...    :|.:||....|.      :....|:..|
Mouse   197 PEVQDAQGTEEPRGGSGGLGARGSGCPGAAEVE----ASPVDDTAAPGPRGNSPGAPGPPATATG 257

  Fly    79 NG-------------------LGDDRK----KRPRTAFSAAQIKALETEFERGKYLSVAKRTALA 120
            .|                   .|.|.|    :|.||||:..|:.|||.:|:..:||||.:|..||
Mouse   258 AGSAGSTPQGAAVTTKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLA 322

  Fly   121 KQLQLTETQIKIWFQNRRTKWKRKYTSDVETLASHYYAQLGIGGLARPMVVGDRLWLFSQTPTGP 185
            ..|.|||||:|||||||||||| |.....:|.|                            |||
Mouse   323 LSLSLTETQVKIWFQNRRTKWK-KQNPGADTSA----------------------------PTG- 357

  Fly   186 TPIQSIMLNGSGSAAPMASATTATGSPMRPYATSGGMPPL-PGPSVMESARNAILARGQPLNFAL 249
                       |...|...|....|.|       ||:.|| |.|.:           |.||....
Mouse   358 -----------GGGGPGPGAGPGAGLP-------GGLSPLSPSPPM-----------GAPLALHG 393

  Fly   250 PFGVAKPPAGGVPAASYIP 268
            |.|......||:..|:.:|
Mouse   394 PAGYPAHSPGGLVCAAQLP 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lms	NP_611491.2	Cnd2	33..>106	CDD:450400	25/104 (24%)
		Homeodomain	87..143	CDD:459649	34/55 (62%)
Nkx1-1	NP_035450.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..82
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..291		19/97 (20%)
		Homeodomain	289..345	CDD:459649	35/56 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	342..387		20/103 (19%)