DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lms and vax1

DIOPT Version :9

Sequence 1:	NP_001286635.1	Gene:	lms / 37322	FlyBaseID:	FBgn0034520	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_919391.2	Gene:	vax1 / 373870	ZFINID:	ZDB-GENE-030904-9	Length:	317	Species:	Danio rerio

Alignment Length:	282	Identity:	94/282 - (33%)
Similarity:	129/282 - (45%)	Gaps:	45/282 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SSTSFEDSVQDESGRGG--NCLGASRASSPATSSCLDDNMDDGKSDI-DLASDDGNGLGDDRKKR 88
            |.|..:|..:..|..|.  || ..|||||.....|....:.|.|..| ::...  .||..||.||
Zfish    33 SKTFLKDQQESFSPSGAVENC-EKSRASSGDPDYCRRILVRDAKGSIREIILP--KGLDLDRPKR 94

  Fly    89 PRTAFSAAQIKALETEFERGKYLSVAKRTALAKQLQLTETQIKIWFQNRRTKWKRKYTSDVE--T 151
            .||:|:|.|:..||.||:|.:|:...:||.||:||.|:|||:|:||||||||.|:....|.|  :
Zfish    95 TRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRS 159

  Fly   152 LASHYYAQLGI------GGLARPMVVGDRLWLFSQTPTGPT---PIQSIMLNG---SGSAAPMAS 204
            :.|...|...:      |.|..|..:...|.....:..|..   |...|..||   |.|::...|
Zfish   160 VVSETAATCSVLRLLEQGRLLTPPGLPGLLPHCGSSSLGSALRGPSLGITANGGSSSSSSSSAGS 224

  Fly   205 ATTATGSPMRPYATSG-------GMPP------LPGPSVMESARNAILARGQPLNFALPFGVAKP 256
            :.||.|||..|..||.       |.||      .|.||::.|..:.|        .:.|.|:|..
Zfish   225 SGTAGGSPPLPTVTSSGTVTGLQGSPPAHGLFSFPMPSLLGSVASRI--------SSTPLGMAGS 281

  Fly   257 PAGGVP--AASYIPRC--KPYA 274
            .||.:.  :|.|:...  :||:
Zfish   282 LAGNLQELSARYLSSSAFEPYS 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lms	NP_001286635.1	Cnd2	33..>106	CDD:303063	28/75 (37%)
lms	NP_001286635.1	Homeobox	89..142	CDD:278475	30/52 (58%)
vax1	NP_919391.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..62		12/29 (41%)
		Homeobox	95..148	CDD:278475	30/52 (58%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	203..248		15/44 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593198
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840