Protein Alignment lms and HMX1

DIOPT Version :9

• Sequence 1: NP_001286635.1
• Gene: lms / 37322
• FlyBaseID: FBgn0034520
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_061815.2
• Gene: HMX1 / 3166
• HGNCID: 5017
• Length: 348
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 82/291 - (28%)
• Similarity: 112/291 - (38%)
• Gaps: 93/291 - (31%)

  Fly     6 AVRRYPHSFSIEQILAKPEMRSSTSFEDSVQ--DESGRG-----------------------GNC 45
            |.|.||.:.........|:    ||..||.:  :|.||.                       |..
Human   113 AARWYPRAHGGYGGGLSPD----TSDRDSPETGEEMGRAEGAWPRGPGPGAVQREAAELAARGPA 173

  Fly    46 LGASRASSPATSSCLDDNMDDGKSDIDLASDD---GNGLGDDRKKRPRTAFSAAQIKALETEFER 107
            .|...||..|              ::..|:.:   |.|:|..|||:.||.||.:|:..||:.|:.
Human   174 AGTEEASELA--------------EVPAAAGETRGGVGVGGGRKKKTRTVFSRSQVFQLESTFDL 224

  Fly   108 GKYLSVAKRTALAKQLQLTETQIKIWFQNRRTKWKRKYTSDVETLASHYYAQLGIGGLARPMVVG 172
            .:|||.|:|..||..|||||||:||||||||.||||:..:::|.      |.|...|..|.:.|
Human   225 KRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLAAELEA------ASLSPPGAQRLVRV- 282

  Fly   173 DRLWLFSQTPTGPTPIQSIMLNGSGSAAPMASATTATGSPMRPYATSGGMPPLPGPSVMESARNA 237
                             .::.:.|..||..|........|:.|.|      |.|.|.:
Human   283 -----------------PVLYHESPPAAAAAGPPATLPFPLAPAA------PAPPPPL------- 317

  Fly   238 ILARGQPLNFALPFGVAKPPAGGVPAASYIP 268
                   |.|:   |....|....|||:.:|
Human   318 -------LGFS---GALAYPLAAFPAAASVP 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lms	NP_001286635.1	Cnd2	33..>106	CDD:303063	24/100 (24%)
		Homeobox	89..142	CDD:278475	31/52 (60%)
HMX1	NP_061815.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..203		21/107 (20%)
		Homeobox	206..259	CDD:278475	31/52 (60%)
		HMX family specific domain 1	263..273		3/15 (20%)
		HMX family specific domain 2	276..289		2/30 (7%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910