Protein Alignment lms and Nkx2-1

DIOPT Version :10

• Sequence 1: NP_611491.2
• Gene: lms / 37322
• FlyBaseID: FBgn0034520
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001390509.1
• Gene: Nkx2-1 / 21869
• MGIID: 108067
• Length: 423
• Species: Mus musculus
• Alignment Length: 297
• Identity: 78/297 - (26%)
• Similarity: 117/297 - (39%)
• Gaps: 81/297 - (27%)

  Fly    31 FEDSVQDESGRGGNCLGA---------SRASSPATSSCLDDNMDDGKSDIDLASDDGNG-LGD-- 83
            ::|:::: |..|....||         ||...||             |.::::...|.| |||
Mouse   151 YQDTMRN-SASGPGWYGANPDPRFPAISRFMGPA-------------SGMNMSGMGGLGSLGDVS 201

  Fly    84 ---------DRKKRPRTAFSAAQIKALETEFERGKYLSVAKRTALAKQLQLTETQIKIWFQNRRT 139
                     .|:|| |..||.||:..||..|::.||||..:|..||..:.||.||:||||||.|.
Mouse   202 KNMAPLPSAPRRKR-RVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRY 265

  Fly   140 KWKRKYTSDVETLASHYYAQLGIGG-----------------------LARPMVVGDRLWLFSQT 181
            |.||:    .:..|:....|...||                       :|.|::|.|.....:..
Mouse   266 KMKRQ----AKDKAAQQQLQQDSGGGGGGGGGAGCPQQQQAQQQSPRRVAVPVLVKDGKPCQAGA 326

  Fly   182 PT-GPTPIQSIMLNGSGSAAPMASATTATGSPMRPYATSGGMPPLPGPSVMESARNAILARGQPL 245
            |. |...:||   :....|...|.|..|..:.:...:...|:...||.....:.::..||.
Mouse   327 PAPGAASLQS---HAQQQAQQQAQAAQAAAAAISVGSGGAGLGAHPGHQPGSAGQSPDLAH---- 384

  Fly   246 NFALPFGVAKPPAGGVPAASYIPRCKPYATSYVDYAA 282
            :.|.|.|:    .|.|.:.|::      .:|..||.|
Mouse   385 HAASPAGL----QGQVSSLSHL------NSSGSDYGA 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lms	NP_611491.2	Cnd2	33..>106	CDD:450400	25/93 (27%)
		Homeodomain	87..143	CDD:459649	29/55 (53%)
Nkx2-1	NP_001390509.1	Homeodomain	213..269	CDD:459649	29/56 (52%)