Protein Alignment lms and Nkx2-6

DIOPT Version :10

• Sequence 1: NP_611491.2
• Gene: lms / 37322
• FlyBaseID: FBgn0034520
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_035050.2
• Gene: Nkx2-6 / 18092
• MGIID: 97351
• Length: 289
• Species: Mus musculus
• Alignment Length: 205
• Identity: 60/205 - (29%)
• Similarity: 82/205 - (40%)
• Gaps: 46/205 - (22%)

  Fly    78 GNGLGDDRK-----------KRPRTAFSAAQIKALETEFERGKYLSVAKRTALAKQLQLTETQIK 131
            ||..||.|:           ::.|..||.||:.|||..|::.:||:..:|..||..||||.||:|
Mouse   104 GNLSGDMRRGGPVSTRTRPQRKSRVLFSQAQVLALERRFKQQRYLTAPEREHLASALQLTSTQVK 168

  Fly   132 IWFQNRRTKWKRKYTSDVETLASHYYAQLGIGGLARPMVVGDRLWLFSQTPTGP--TPIQSIMLN 194
            |||||||.|.|.:.......||.|                          |..|  ..:..::|:
Mouse   169 IWFQNRRYKSKSQRQDQTLELAGH--------------------------PLAPRRVAVPVLVLD 207

  Fly   195 GSGSAAPMASATTATGSPMRPYATSGGMPPLPGPSVMESARNAILARGQPL------NFALPFGV 253
            |.....|..:|.........||:..||....|..:...|...:..|...||      .|: |.|.
Mouse   208 GKPCLDPDVAAFLGPYKATSPYSCFGGYAGTPYDASYASRCTSASAGPGPLTPLASSGFS-PGGQ 271

  Fly   254 AKPPAGGVPA 263
            :..|.|.:||
Mouse   272 SAAPQGHLPA 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lms	NP_611491.2	Cnd2	33..>106	CDD:450400	13/38 (34%)
		Homeodomain	87..143	CDD:459649	29/55 (53%)
Nkx2-6	NP_035050.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..125		5/20 (25%)
		Homeodomain	124..179	CDD:459649	29/54 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	259..289		7/24 (29%)