DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lms and mls-2

DIOPT Version :9

Sequence 1:	NP_001286635.1	Gene:	lms / 37322	FlyBaseID:	FBgn0034520	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_508815.2	Gene:	mls-2 / 180751	WormBaseID:	WBGene00003377	Length:	341	Species:	Caenorhabditis elegans

Alignment Length:	202	Identity:	68/202 - (33%)
Similarity:	99/202 - (49%)	Gaps:	36/202 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LAKPEMR-SSTSFEDSVQDESGRGGNCLGASRASSPATSSCLDDNMDDGKSDIDLASDDGNGLGD 83
            ::.|::. .|.:.|:..:...|:.|.... |...||..|...||:      ||...|||.....|
Worm   138 MSNPDVNIQSDNGEEKDEKSEGKDGETRD-STGGSPLESDAEDDD------DIGRGSDDEANSSD 195

  Fly    84 ---DRKKRPRTAFSAAQIKALETEFERGKYLSVAKRTALAKQLQLTETQIKIWFQNRRTKWKRKY 145
               :|||:.||.||.:|:..||..||..:|||..:|:.||::|.|||||:||||||||.|:||:.
Worm   196 PSQNRKKKTRTVFSRSQVSQLEMMFECKRYLSSQERSNLAQKLHLTETQVKIWFQNRRNKFKRQA 260

  Fly   146 TSDVETLASHYYAQLGIGGLARPMVVGDRLWLFS--QTPTGPTPIQSIMLNGSG------SAAPM 202
            .:|...::...:                |..:||  .|....:||.:|....:|      .::||
Worm   261 QTDDTNISLQMH----------------RANVFSIPATTALTSPILTIPTTSAGVNMRNMISSPM 309

  Fly   203 -ASATTA 208
             ||||.|
Worm   310 DASATAA 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lms	NP_001286635.1	Cnd2	33..>106	CDD:303063	24/75 (32%)
lms	NP_001286635.1	Homeobox	89..142	CDD:278475	30/52 (58%)
mls-2	NP_508815.2	Homeobox	204..258	CDD:395001	30/53 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I3757
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960