Protein Alignment CD82 and Tsp5D

DIOPT Version :10

• Sequence 1: XP_047282856.1
• Gene: CD82 / 3732
• HGNCID: 6210
• Length: 308
• Species: Homo sapiens
• Sequence 2: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Alignment Length: 284
• Identity: 80/284 - (28%)
• Similarity: 133/284 - (46%)
• Gaps: 38/284 - (13%)

Human    40 GGMGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVL-QTSSSSLRMGAYVFIGV 103
            |..|..||:.|  |.:| |:|.::.....||.|:|:....:.:.::| |.:..|   ...:|:|:
  Fly     2 GNAGYTCIRRT--FCWL-NIILWLCSCAFLGAGLWLRLSYAGYATLLPQHAGLS---ADTIFMGI 60

Human   104 GAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMG-----GIVT 163
            |....::.|.||.||..:.||||.|||..::::.:::...|::.:...|.|.:.:.     ||.
  Fly    61 GGTGFVVSFFGCCGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRFGIE- 124

Human   164 ELIRDYNSSREDSL-----QDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEE 223
               |.||||...||     ...||.||...:|||..|:.:|.|......|..|...| |....::
  Fly   125 ---RHYNSSDRGSLVAPSVASIWDSVQQSFECCGVSSYEDWYDIQSWPGRRWVPESC-CRTLYDQ 185

Human   224 DNSLSVRKGFCEAPGN---RTQSG--NHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIE 283
                  |:...|..|:   |...|  .:|..|  :.:||...:|:|....|.::..||:|:|.::
  Fly   186 ------RQVLTEGSGDGMMRPDCGRSENPSLW--WDKGCAHSLQSWFTGQLNVVGAVGLGIAFVQ 242

Human   284 LLGMVLSI---CLCRHVHSEDYSK 304
            |.|::.|:   |..:|..:.|..|
  Fly   243 LFGLITSMLLFCTVKHKRASDTYK 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CD82	XP_047282856.1	Tetraspanin	65..295	CDD:459767	68/248 (27%)
		CD37_CD82_like_LEL	147..270	CDD:239413	36/137 (26%)
Tsp5D	NP_001259266.1	Tetraspanin	9..254	CDD:459767	73/263 (28%)
		NET-5_like_LEL	105..228	CDD:239418	36/135 (27%)