DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cpr57A and ADA2

DIOPT Version :9

Sequence 1:	NP_001137721.1	Gene:	Cpr57A / 37319	FlyBaseID:	FBgn0034517	Length:	184	Species:	Drosophila melanogaster
Sequence 2:	NP_010736.3	Gene:	ADA2 / 852059	SGDID:	S000002856	Length:	434	Species:	Saccharomyces cerevisiae

Alignment Length:	220	Identity:	45/220 - (20%)
Similarity:	66/220 - (30%)	Gaps:	65/220 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 PEPKVPASPYVFSYQAGR----------APGHVDRQHTEVSDGSGVIRGAFSYVDPKNQVRTVQY 77
            |...||:...|..:..||          |.|.|.....|..|....|...|:.:|..|...|.:.
Yeast   152 PMASVPSCHEVQGFMPGRLEFETEFENEAEGPVKDMVFEPDDQPLDIELKFAILDIYNSRLTTRA 216

  Fly    78 VADEHGFHPQLS--HKLE--DSAAVQAAKQRHFAAYNRI--------AQEHANHTPGQVALANAP 130
            ......|...|.  .||:  |....:.||:    .||||        ||:....:..   :....
Yeast   217 EKKRLLFENHLMDYRKLQAIDKKRSKEAKE----LYNRIKPFARVMTAQDFEEFSKD---ILEEL 274

  Fly   131 HASAAVAHA--------------------TQKHLSAFERIAAEHAAI---GRQQEAQRLALAAQS 172
            |..|.:...                    .|..:|:||:..|..||.   |..:.....|..:.:
Yeast   275 HCRARIQQLQEWRSNGLTTLEAGLKYERDKQARISSFEKFGASTAASLSEGNSRYRSNSAHRSNA 339

  Fly   173 EHGE-------------IEDGQYHP 184
            |:.:             |.|.|:.|
Yeast   340 EYSQNYSENGGRKKNMTISDIQHAP 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cpr57A	NP_001137721.1	Chitin_bind_4	32..84	CDD:278791	13/61 (21%)
ADA2	NP_010736.3	COG5114	3..434	CDD:227445	45/220 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.924933	Normalized mean entropy	S1795
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950