DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cpr57A and NOTCH2

DIOPT Version :9

Sequence 1:NP_001137721.1 Gene:Cpr57A / 37319 FlyBaseID:FBgn0034517 Length:184 Species:Drosophila melanogaster
Sequence 2:NP_077719.2 Gene:NOTCH2 / 4853 HGNCID:7882 Length:2471 Species:Homo sapiens


Alignment Length:47 Identity:14/47 - (29%)
Similarity:17/47 - (36%) Gaps:15/47 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 KVPASP----YVFSYQAGRAPGHVDRQHTEVSDGSGVIRGAFSYVDP 68
            |.|..|    |..|..|.|.|.|           ||.::|...|:.|
Human  2382 KYPTPPSQHSYASSNAAERTPSH-----------SGHLQGEHPYLTP 2417

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cpr57ANP_001137721.1 Chitin_bind_4 32..84 CDD:278791 11/37 (30%)
NOTCH2NP_077719.2 EGF_CA 182..218 CDD:238011
EGF_CA 260..296 CDD:238011
EGF_CA 298..335 CDD:238011
EGF_CA 415..454 CDD:238011
EGF_CA 456..492 CDD:238011
EGF_CA 495..530 CDD:238011
EGF_CA 532..568 CDD:238011
EGF_CA 570..604 CDD:238011
EGF_CA 608..643 CDD:238011
EGF_CA 645..679 CDD:238011
EGF_CA 682..717 CDD:238011
EGF_CA 757..793 CDD:238011
EGF_CA 795..831 CDD:238011
EGF_CA 873..909 CDD:238011
EGF_CA 911..947 CDD:238011
EGF_CA 949..985 CDD:238011
EGF_CA 987..1022 CDD:238011
EGF_CA 1026..1061 CDD:238011
EGF_CA 1117..1147 CDD:238011
EGF_CA 1151..1185 CDD:238011
EGF_CA 1188..1223 CDD:238011
EGF_CA 1225..1262 CDD:238011
EGF_CA 1264..1302 CDD:238011
EGF_CA <1312..1343 CDD:238011
Notch 1423..1456 CDD:278494
Notch 1463..1497 CDD:278494
Notch 1501..1534 CDD:278494
NOD 1540..1591 CDD:284282
NODP 1620..1673 CDD:284987
Ank_2 <1820..1907 CDD:289560
ANK repeat 1827..1874 CDD:293786
ANK 1872..1997 CDD:238125
ANK repeat 1877..1907 CDD:293786
Ank_2 1881..1974 CDD:289560
ANK 1938..2062 CDD:238125
ANK repeat 1943..1974 CDD:293786
Ank_2 1948..2040 CDD:289560
ANK repeat 1976..2007 CDD:293786
ANK repeat 2009..2040 CDD:293786
Chorion_3 <2292..2421 CDD:253174 14/47 (30%)
DUF3454 2381..2444 CDD:288764 14/47 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0.924933 Normalized mean entropy S1795
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.950

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