DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13423 and blmh

DIOPT Version :9

Sequence 1:	NP_611485.1	Gene:	CG13423 / 37315	FlyBaseID:	FBgn0034513	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_956312.1	Gene:	blmh / 336541	ZFINID:	ZDB-GENE-030131-8485	Length:	453	Species:	Danio rerio

Alignment Length:	490	Identity:	161/490 - (32%)
Similarity:	240/490 - (48%)	Gaps:	62/490 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LTEPQWSAWYSAFYASSMNRLAQNVCTAQDPITVCLRSEA--DLC-----SVPSGVKTWIELSRQ 62
            |::.:.||:...|.:.....|||||.|..||:.|||..:.  |..     |:|:          :
Zfish     5 LSQEKASAFVKRFRSEPRYLLAQNVSTCIDPLEVCLHRQTVQDTVHIFQHSIPT----------E 59

  Fly    63 GKATT----GGPGWICTGLDLLCQEMDRKLPLPLDFELSAAHLFFWHKLERCNYFLWTVADLLMR 123
            ||..|    .|..||.:.|:::.....:|..:. :||.|.::||||.|:|||.:||....:...|
Zfish    60 GKPVTNQKNSGRCWIFSCLNVMRLPFMKKFNIE-EFEFSQSYLFFWDKVERCYFFLHACVETAQR 123

  Fly   124 CEPLDGRCFRNLIKNPVPDGGNWQMFVNLVKKYGVMPKKCY--LHSTQRTTKMNLILKSKLREYA 186
            .||:|||..:.|:.||..|||.|.|.|||::||||:||||:  .||::.:.:||.||..|:|||.
Zfish   124 KEPVDGRLVQFLLSNPTNDGGQWDMLVNLIEKYGVVPKKCFPESHSSEASRRMNDILNHKMREYC 188

  Fly   187 SMLHAQFTFNGNGCRLPDLIQEMIPHLFKVICICLGEPPKVFTWSFYDHKKRYQCLNDMTAVHFY 251
            ..|............:.:.|..||..:|:|..:|||.||....|.:.|..|.:..|..:|.:.||
Zfish   189 LRLRNMVASESTKTEISETIDTMIEEVFRVASVCLGSPPDTICWEYRDKDKNFHHLGPLTPLEFY 253

  Fly   252 EVMVGCTVNLDAFVCLGHDPRISSSYHSNYQVANSSNMMGGKPHRYNNQSMDIIMQIMVTSLEGD 316
            ...|....||...:||.:|||..:.|...|.|...|||:||:...||||.::::.:....|::..
Zfish   254 TEHVKPLYNLQDKICLVNDPRPQNPYGKLYTVEFLSNMVGGRKTLYNNQPVELLKKAAADSIKKG 318

  Fly   317 KPVWMACDIRRAISLKSGPLSLRSHQFDLLFGFKVGESLTKAERLDYRASRRDAALLLTSVGLDT 381
            :.||..||:.:....|.|...:.....||:||..| ::|:|||||.|..|....|::||:|....
Zfish   319 EAVWFGCDVGKHFHSKLGINDMNVFNHDLVFGVSV-KNLSKAERLIYGDSMMTHAMILTAVTDKV 382

  Fly   382 LKQPVQFRFINASTIGESPATGGLNEHDVDEKVTKALRKKSVKPPDNK----LDAEWLREYAFEI 442
            .|:....::...::.|:...                          ||    :..||..||.:|:
Zfish   383 GKEACYEKWRVENSWGDDRG--------------------------NKGYLIMTDEWFSEYVYEV 421

  Fly   443 VVHEKFVPSGVLHAARIHKWKE---LPAWDPMGAL 474
            ||.:.|:...||...:    |:   ||||||||||
Zfish   422 VVDKSFLSPEVLDVMQ----KDPVVLPAWDPMGAL 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13423	NP_611485.1	Peptidase_C1	5..472	CDD:304901	157/486 (32%)
blmh	NP_956312.1	Peptidase_C1B	5..450	CDD:238328	157/486 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595590
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D308225at33208
OrthoFinder	1	1.000	-	-		FOG0007157
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10363
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.810