DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slc2a8 and CG33282

DIOPT Version :9

Sequence 1:	NP_997963.1	Gene:	slc2a8 / 373140	ZFINID:	ZDB-GENE-030829-25	Length:	498	Species:	Danio rerio
Sequence 2:	NP_001097067.1	Gene:	CG33282 / 2768939	FlyBaseID:	FBgn0053282	Length:	460	Species:	Drosophila melanogaster

Alignment Length:	493	Identity:	121/493 - (24%)
Similarity:	212/493 - (43%)	Gaps:	74/493 - (15%)

- Green bases have known domain annotations that are detailed below.

Zfish    31 VKNGKL-------FIATFAAVLGPLSFGFVLGYSSPAIPELRRIQD-LRLQLSVEEASWFGSVVT 87
            :||..|       .:||....:.....|..:|:.||.:.:::.... |..::::.:.||.||::.
  Fly     5 LKNSLLQQKTRYQLLATVIVNIITFGHGVGVGWLSPTLTKIQTADSPLDFEVNLAQISWLGSMLG 69

Zfish    88 IGAALGGLLGGWIVERIGRKLSLMFCAIPFIFGFTTIIAAQNHWMFYVGRVLTGLASGVTSLVVP 152
            :.:..|.|....::||.|||..|...|.|:...:..|..|.|.:..|..|.|.|...|...||||
  Fly    70 LDSLCGNLTIAMLIERAGRKFCLYLMAGPYACIWILIYCASNVYYLYAARFLCGFTGGAGYLVVP 134

Zfish   153 LYISEMAHERVRGTLGSCVQLMVVIGIMGAYVTGLFLDWRWLAVASSIPPTLMLLSMCFMPETPR 217
            ::|||:|...:||.|.|.|.|.|.:||:..|:...:|.:..:...:.|.|....::...:|||..
  Fly   135 IFISEVADSNIRGALTSMVMLSVDLGILAGYILSTYLAYHVVPFLAIILPVAYFIANIMLPETAP 199

Zfish   218 FLLCQGKRREAEDALRFLRGPDAP----------AEWECARIEDAYKNEEQSFSLGDLKDPGVYK 272
            :||.:.:...||::.|:.|...:.          .|...|.:....:| ....|..||......|
  Fly   200 YLLKKSQLAAAENSFRYYRNQRSAICEQTSKVNFEELRTAVLSQQTRN-ATPLSYKDLTTKPALK 263

Zfish   273 PLGIGVMMMLLQQFTGINAIMFYAETIFEQAHFKSS------DVATVIVAATQVVFTAIAALIMD 331
            .....:::.|..||:|:.:.:.|...|     ||:|      :.||:|:...|:|....:.:::|
  Fly   264 GFAASIVLSLGYQFSGVFSFINYMSDI-----FKASGSVVDVNTATIIIGLVQIVGVYTSTILVD 323

Zfish   332 KAGRKVLLILSGVVMCVSEAVFGVYFKLTVMKPNNSSMTSVLTDTHGLLEDQPSADLAWLA---- 392
            ..||:||:::|.:.:.:....||.:              :.|...:.|      :|..||.
  Fly   324 IVGRRVLMLISTMGVGIGCIAFGCF--------------TYLAKIYDL------SDFNWLPLVLM 368

Zfish   393 --------VGSMGFFIAGFAIGWGPTPWLVMSEIFPTRVRGLGSALCVLTNWTCAFIVTKTFQNL 449
                    :|.:|.|            :||:.|:||.::|.|.::|.|:......|...|.|..:
  Fly   369 IIICYVANIGLIGIF------------FLVLVELFPVKIRSLATSLSVIFLSLLVFGTLKLFPLM 421

Zfish   450 MDALSSAGTFWMFSALCASNVVFTAFFVPETKGKTLEE 487
            :.....:.|.|..:|.......:...|:.|||||::.|
  Fly   422 LHYWGISFTMWFSAASALLTFFYFWLFLQETKGKSMIE 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slc2a8	NP_997963.1	Sugar_tr	39..492	CDD:278511	118/478 (25%)
slc2a8	NP_997963.1	MFS	40..477	CDD:119392	110/465 (24%)
CG33282	NP_001097067.1	MFS	21..448	CDD:119392	110/464 (24%)
CG33282	NP_001097067.1	MFS_1	53..409	CDD:284993	98/393 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576973
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.040