DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment xiap and Bruce

DIOPT Version :9

Sequence 1:	NP_919377.2	Gene:	xiap / 373108	ZFINID:	ZDB-GENE-030825-7	Length:	405	Species:	Danio rerio
Sequence 2:	NP_001262460.1	Gene:	Bruce / 41260	FlyBaseID:	FBgn0266717	Length:	4976	Species:	Drosophila melanogaster

Alignment Length:	374	Identity:	79/374 - (21%)
Similarity:	117/374 - (31%)	Gaps:	115/374 - (30%)

- Green bases have known domain annotations that are detailed below.

Zfish     9 ELESDNVAADWSV---MKNRVNSFQRFPYSEDISAQRLARAGFYFTGEGDRVQCFSCSATVQNWN 70
            ||||:.:.....:   :..::|           .||..|:.|.                ..|.||
  Fly   142 ELESEGLECPCDISNELTQKIN-----------QAQLKAKKGI----------------KAQRWN 179

Zfish    71 R--GDTP-----------------LERH----QLASP-DCRFLSCAHGMRNSNSIQSPDYDEEAE 111
            .  .:.|                 ||||    .:||. :.|......|.|      .||:.....
  Fly   180 TICLEVPYSSLKLVSNNMVILLKRLERHIPVLAIASAINERLTDMMMGSR------VPDFGWNFS 238

Zfish   112 NREFLLRTGEVVDESMYPVVPHMKSEEARLSTFNNWP-ADSP-VRPEDLAEAGMYY---IGIDDN 171
            |.:.:|                |.||..|..||..|| .|.. ..|:.:|:||.|:   ...:|.
  Fly   239 NFQRVL----------------MHSEAVRRQTFEKWPHMDYKWALPDQMAQAGFYHQPSSSGEDR 287

Zfish   172 VQCFCCGGGLSGWEQGDDPWSEHAKYYSNCFFFLGHNVGNVPLTTPRPRVNVHPTDTFEGRLDSF 236
            ..||.|...|..||:.|:|||||.::...|.|..|....||||                    |.
  Fly   288 AMCFTCSVCLVCWEKTDEPWSEHERHSPLCPFVKGEYTQNVPL--------------------SI 332

Zfish   237 KGRQHPIDPERLARAGFYSTGEQDRVMCFRCG--GGVKAWMPDEDPWEEHARHYPGCSFLLAEKG 299
            ....:|..|.........|..:...|:|..|.  |.:..|..:......|..|.|.....:.|:.
  Fly   333 TYATNPALPAPGLGFDIISNSDYANVLCTSCSQTGELSVWSIERHLKLMHTFHVPTLLNYIFEES 397

Zfish   300 EEYV------------SSVQLRYPKRPTQNGFSSHESGSSAQALIHGSS 336
            .|:.            :..::.|.......|.|...:|:...:.::..|
  Fly   398 FEWARVTAICVLPNARARTKVNYVYSAANYGGSGSSNGAGCNSGLNAVS 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
xiap	NP_919377.2	BIR	23..89	CDD:237989	16/89 (18%)
		BIR	138..206	CDD:237989	26/72 (36%)
		BIR	230..296	CDD:237989	12/67 (18%)
		zf-C3HC4_3	354..398	CDD:290631
Bruce	NP_001262460.1	BIR	251..321	CDD:279047	26/69 (38%)
		DUF3643	3539..3664	CDD:289152
		UQ_con	4636..4790	CDD:278603
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910