Protein Alignment side-VIII and LOC1281351

DIOPT Version :10

• Sequence 1: NP_001097382.2
• Gene: side-VIII / 37310
• FlyBaseID: FBgn0086604
• Length: 1201
• Species: Drosophila melanogaster
• Sequence 2: XP_061499696.1
• Gene: LOC1281351 / 1281351
• VectorBaseID: AGAMI1_001755
• Length: 1092
• Species: Anopheles gambiae
• Alignment Length: 1277
• Identity: 522/1277 - (40%)
• Similarity: 678/1277 - (53%)
• Gaps: 307/1277 - (24%)

  Fly    11 LPLCLLVLSALNGPAAAASRVRVSSSTTMTRNIEEENALLLLLAGPPVLSESIMGTVGRLPCNVT 75
            |...|:||..:....:|.|   |...|:..::.|.||.       |..|||::.||||:|.||:|
Mosquito    28 LAALLVVLYVVLAQLSAGS---VVEGTSSGKDGEYENT-------PLHLSEAVQGTVGQLECNIT 82

  Fly    76 PPIYEDRVALVIWYKVGLKTPIYSVDTRDSNFAQGTH-WSDETYRERLSFHVEGRAGTLTIKSTT 139
            .||..||..||||||.....|.|:.|.||  ..:|:| .|:.::..|.:|:.......|.|..|.
Mosquito    83 SPISGDRAILVIWYKGAQTIPFYTFDARD--VREGSHRSSNSSFDGRTNFYPNRTPAMLEILQTK 145

  Fly   140 EDDTGEYRCRVDFQKSPTRNSKVNLTVIIPPESVIILDSKGVTIEDHTLGPYNEGSGINITCVAI 204
            ..|:|.|||||||.||||||::|.||||:|||.::|:|.||..|..:.|||||||:.|||||::.
Mosquito   146 PTDSGIYRCRVDFHKSPTRNTRVQLTVIVPPEKLLIVDEKGSHIRHYILGPYNEGATINITCIST 210

  Fly   205 GGRPQPRVTWLHGNTVYKNASVGQPLSERRVGNTLSLARLERRNLHMQLTCRAENNNLTTPIISS 269
            ||||.|:|.|.:.|.|..|.||  .||::||.|||.|.||||::|....||:|.|||:|.||.:|
Mosquito   211 GGRPLPKVQWWYENKVINNTSV--VLSDKRVKNTLVLHRLERKHLKSVFTCQASNNNVTNPISAS 273

  Fly   270 VVLDMNLRPLIVKLQGENRALSAGNSYQLSCVVIGARPAPTITWWKGSTPMKNTHEIATPDGNLT 334
            :.||||||||.|:|||:||.|||.::|.|.|.|:|:|||||||||||||.|:..||...||||:|
Mosquito   274 ITLDMNLRPLSVRLQGKNRPLSANHTYDLQCEVLGSRPAPTITWWKGSTQMRGHHETTDPDGNVT 338

  Fly   335 TSVLTFTPTIDDRGKFLSCRAEQSMIPESGMEDGWKLDIYHIPVVSLELGTN-SLNSTLREGIDV 398
            .|:|:|.|||||:||:||||||.::||::|.||||||||||:|||:||.||| :..|::.||:||
Mosquito   339 VSILSFRPTIDDKGKYLSCRAEMAVIPDAGKEDGWKLDIYHVPVVTLEYGTNYNYTSSIPEGVDV 403

  Fly   399 FFECNIKSNPWIYEVSWRHNGKILTNNPAEGIAVSNQSLVLQNASRARSGIYTCVGSNREGDGES 463
            :||||||||||:|:|.|||.||.|.|||:||:.||||||||||.||.|:|.||||||||||||||
Mosquito   404 YFECNIKSNPWVYKVIWRHYGKELVNNPSEGVTVSNQSLVLQNVSRNRAGQYTCVGSNREGDGES 468

  Fly   464 NPVQLDIRFAPVCRPRQRLSYSSGRHETVKVACEIDANPAEATYVWKFNATQGETVDIPASQVAV 528
            |||.|||:|||||||....:|:.||:|..|:.||::|||:..|:.||:|.:..|::|||||:|..
Mosquito   469 NPVHLDIKFAPVCRPGLVTTYNVGRNELAKIVCELEANPSNVTFTWKYNTSVSESLDIPASEVLS 533

  Fly   529 DRGRSIAHYTPMTENDYGTLLCWATNEIGDQSEPCVYTIFPAGEPDPLLNCTVLNQTSTGFQIEC 593
            ||.:|:||:.|:||.||||||||..||||.|:|||::.:.|||:||||.|||:||||....||||
Mosquito   534 DRTKSVAHFKPVTEKDYGTLLCWGRNEIGAQTEPCLFNLIPAGKPDPLSNCTILNQTFDMLQIEC 598

  Fly   594 IEGFNGGLQQDFIMEVYMNGTTRHPKISKSKRPYFEVSGLVPGMGYNVFLIANNSKGRSNATILQ 658
            :||::|||.|.|.:|:|:.|:.:.....||..|.|::.||.||:|||:.|.|.||||.|:.|.||
Mosquito   599 LEGYDGGLPQVFQIELYVIGSRQQMTSIKSTSPAFDLKGLEPGVGYNIILTAKNSKGSSDPTYLQ 663

  Fly   659 VYTLKDPEKQTVKITFTKSFQGLRPAYTKTKATATTTSDCVCDEDEFLNLGKGISHDEGTDADQQ 723
            .:|||:|||||
Mosquito   664 AFTLKNPEKQT------------------------------------------------------ 674

  Fly   724 EDLSLAYAPVIEDIRPFLGILAGIVGSIFLVALIIVIVVRVRGSSGRDRNNYSHPGSGVGGVGGV 788
             ||||.|.|.:..|:||:|.|.|:|.:|..:|.|||.|.|:|||:||||:
Mosquito   675 -DLSLVYPPALLQIKPFIGTLLGVVAAIISIASIIVCVTRLRGSAGRDRD--------------- 723

  Fly   789 GGTTGNGSGMGGGGGGVGGTTANGNGSLGLLASNNNGSLVIGTLGHNGGQSVQDMHRIGRETCHV 853
                 .||.|                      |.|:.|.:        .||:.|.. :.||.|:
Mosquito   724 -----CGSNM----------------------STNDASGI--------SQSIPDAD-LAREQCN- 751

  Fly   854 TSSLDSIDKNPDIIPQDG--HDLDD-----EW-TTKGHGRTYATAAMAEQNA------VITSGTY 904
             .|:|||:||||||||..  |.|.:     || ....|.|.|||||||||.:      ...:.||
Mosquito   752 -GSIDSIEKNPDIIPQAKLLHLLKEDEKAFEWLNNAAHPRLYATAAMAEQQSGGLLPPSAAAATY 815

  Fly   905 DHLMPTYAVVDKKTAPPPGHGQYIQYNTLIPVSKMGAYANQQQQLQQQPQQ-------------- 955
            | ....||                          :...|.||||.|||.||
Mosquito   816 D-TRAFYA--------------------------LARDAQQQQQQQQQQQQNCMQQNVYPVASSD 853

  Fly   956 -------------------------KTELSYSELSAPLVS----GPVGVQRMAP-----YCSATL 986
                                     |.:|:|::||   :|    |..|:.::.|     |.||||
Mosquito   854 GQSYIPMHGTIISTPIVGGYGSDGHKHDLTYADLS---ISGGGGGAGGMPKLNPGQPQMYVSATL 915

  Fly   987 GRPGRQAELKRAEPNIYSQVNVMMDDEILADLQAATASGRSYVAGAVVDNVGGAPNLYVQGYATR 1051
            ||| ||:::||:||.||:|
Mosquito   916 GRP-RQSDIKRSEPTIYAQ---------------------------------------------- 933

  Fly  1052 IDLAHHPMPMYSTSPMFGTNSTITGVTMSH------------------------PSQLATFS--P 1090
            ||||||| .::||:.:: ||:....:.:||                        |.|.|..|  |
Mosquito   934 IDLAHHP-GVHSTNLVY-TNAPRHSIPISHATGLPVSGAHLLQQQQQHTVPVQSPLQRAPDSGQP 996

  Fly  1091 T-----PPPPIFTHSMVTTGDGLLQPVTCMGLVATSSAGASVPGPVPLAPQQQQQQQLTAANGGN 1150
            :     ||||:|..|:..:|    |.........|.......|.|:|..|......:.|||....
Mosquito   997 SLTERYPPPPLFGGSLPVSG----QQHCANEPFFTIPPPPPSPPPLPPPPPPIPPPKPTAAGTSK 1057

  Fly  1151 GSIVGMGMSLYGSDVGKPQLLKTVPEEVHHQLNGEDILIAQD 1192
            .|   :.|:.|.............|..|..|    ..|||.:
Mosquito  1058 PS---LNMAQYSQRRTLQSFFDASPPNVTEQ----TCLIASE 1092

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
side-VIII	NP_001097382.2	IG_like	60..166	CDD:214653	50/106 (47%)
		Ig strand B	69..72	CDD:409353	1/2 (50%)
		Ig strand C	85..89	CDD:409353	3/3 (100%)
		Ig strand E	131..135	CDD:409353	1/3 (33%)
		Ig strand F	145..150	CDD:409353	3/4 (75%)
		Ig	189..273	CDD:472250	46/83 (55%)
		Ig strand B	197..201	CDD:409353	3/3 (100%)
		Ig strand C	211..215	CDD:409353	1/3 (33%)
		Ig strand E	237..241	CDD:409353	3/3 (100%)
		Ig strand F	252..257	CDD:409353	2/4 (50%)
		Ig strand G	267..270	CDD:409353	0/2 (0%)
		Ig	290..373	CDD:472250	54/82 (66%)
		Ig strand B	296..300	CDD:409353	2/3 (67%)
		Ig strand C	310..314	CDD:409353	3/3 (100%)
		Ig strand F	350..355	CDD:409353	3/4 (75%)
		Ig strand G	366..369	CDD:409353	2/2 (100%)
		Ig_3	377..456	CDD:464046	55/79 (70%)
LOC1281351	XP_061499696.1	None