Protein Alignment side-VIII and side-VII

DIOPT Version :10

• Sequence 1: NP_001097382.2
• Gene: side-VIII / 37310
• FlyBaseID: FBgn0086604
• Length: 1201
• Species: Drosophila melanogaster
• Sequence 2: XP_061497694.1
• Gene: side-VII / 1274072
• VectorBaseID: AGAMI1_004651
• Length: 918
• Species: Anopheles gambiae
• Alignment Length: 1048
• Identity: 335/1048 - (31%)
• Similarity: 469/1048 - (44%)
• Gaps: 204/1048 - (19%)

  Fly    56 PPVLSESIMGTVGRLPCNVTPPIYEDRVALVIWYKVGLKTPIYSVDTRDSNFAQGTHWSDET-YR 119
            |.|..|:::|....|||||:.....|.|.||:||:....:||||.|||.........|||:: :.
Mosquito    28 PVVAMEALVGETIYLPCNVSTHEPGDNVVLVLWYREDKGSPIYSADTRGREVGSAKRWSDDSMFG 92

  Fly   120 ERLSFHVEGRAGTLTIKSTTEDDTGEYRCRVDFQKSPTRNSKVNLTVIIPPESVIILDSKGVTIE 184
            :|..|..|...|.|.:::..|.|:|.|||||||..:.||||.||||:|:|||.::|.|..|  :|
Mosquito    93 DRAYFQFEKEPGELAVQNVRETDSGMYRCRVDFIVAQTRNSVVNLTIIVPPERMVIRDQLG--ME 155

  Fly   185 DHTL-GPYNEGSGINITCVAIGGRPQPRVTWLHGNTVYKNASVGQPLSERRVGNTLSLARLERRN 248
            ..|: |||:||..|.:.|...||||.|.|||..........:...||. :.:.:.::|..|.|::
Mosquito   156 RTTVAGPYSEGDNIKLRCDVYGGRPTPTVTWYRDGVAMVADTKYMPLG-KHLRSEIALGPLTRQD 219

  Fly   249 LHMQLTCRAENNNLTTPIISSVVLDMNLRPLIVKLQGENRALSAGNSYQLSCVVIGARPAPTITW 313
            ||.:|.|||.|:....|:..||.:|||..||.::|.|.::.||||..|.|.|...|:|||.:|||
Mosquito   220 LHTKLVCRASNHARANPVEQSVQIDMNFAPLNIRLIGAHQPLSAGRRYDLLCQSAGSRPAASITW 284

  Fly   314 WKGSTPMKNTHEIATPDGNLTTSVLTFTPTIDDRGKFLSCRAEQSMIPESGMEDGWKLDIYHIPV 378
            :.....:..:.|..:.|||.|||.|:......|.||:|||:|..:.:....:||||:|||.::|.
Mosquito   285 FLDGVRLDKSKETTSADGNQTTSTLSIVLNRTDAGKYLSCKAYNTYVQSDALEDGWQLDIQYVPD 349

  Fly   379 VSLELGTNSLNSTLREGIDVFFECNIKSNPWIYEVSWRHNGKILTNNPAEGIAVSNQSLVLQNAS 443
            .|:.||::.....:|||.||:|:|.:|::|.:|:|.|:||.|.||.|.::|:.||..|||||..|
Mosquito   350 ASVRLGSSLDPDAIREGTDVYFDCIVKAHPAVYKVEWKHNNKTLTRNISQGVIVSKHSLVLQGVS 414

  Fly   444 RARSGIYTCVGSNREGDGESNPVQLDIRFAPVCRPRQRLSYSSGRHETVKVACEIDANPAEATYV 508
            |..:|.|||||.|.||:|.|...:|::.:||.|.|.|...|...:.|..::.|.:||||.:..:.
Mosquito   415 RTTAGNYTCVGFNAEGEGSSPTFELNVMYAPTCAPNQPRVYGVAKQENAEIRCVVDANPPDVEFK 479

  Fly   509 WKFNATQGETVDIPASQVAVDRGRSIAHYTPMTENDYGTLLCWATNEIGDQSEPCVYTIFPAGEP 573
            |.|| ...|::|:.||.::.....||..||||.|.|||||||.|||:||.|.:|||:.|..||.|
Mosquito   480 WTFN-NSAESIDVQASHISRLGTSSIVSYTPMIELDYGTLLCSATNKIGKQRQPCVFHIIAAGRP 543

  Fly   574 DPLLNCTVLNQTSTGFQIECIEGFNGGLQQDFIMEVYMNGTTRHPKISKSKRPYFEVSGLVPGMG 638
            |.:.||||.|.:.|...:.|.|||||||.|.|.:|:..:.:......:.|..|.|.|..|.|...
Mosquito   544 DQVHNCTVANVSMTSLAVRCYEGFNGGLAQSFFLELRDSHSQEMRFNNTSPVPRFTVPNLHPSAV 608

  Fly   639 YNVFLIANNSKGRSNATILQVYTLKDPEKQTVKITFTKSFQGLRPAYTKTKATATTTSDCVCDED 703
            |.:.:.|.||||||...::...|.:.||||
Mosquito   609 YQLAVYAFNSKGRSEPYVMSAATQRLPEKQ----------------------------------- 638

  Fly   704 EFLNLGKGISHDEGTDADQQEDLSLAYAPVIEDIRPFLGILAGIVGSIFLVALIIVIVVRVR-GS 767
                            ....|.:....:|:  .:.|.|.|..|:..::.:.:..||:.::.. |:
Mosquito   639 ----------------MKDSEKVERPRSPL--PLTPTLSIAIGLAAAVLIGSCAIVLALKFPCGA 685

  Fly   768 SGRDRNNYSHPGSGVGGVGGVGGTTGNGSGMGGGGGGVGGTTANGNGSLGLLASNNNGSLVIGTL 832
            ||| ||..:           ..|||...|..|.....|.....:||
Mosquito   686 SGR-RNKET-----------AQGTTVRTSSPGPSDKSVASKEYDGN------------------- 719

  Fly   833 GHNGGQSVQDMHRIGRETCHVTSSLDSIDKNPDIIPQDGHDLDDEWTTKGHGRTYATAAMAEQNA 897
                                     :|.:||||:|| |..|.||:.......:..:|
Mosquito   720 -------------------------ESDEKNPDVIP-DTIDSDDQMEYIKRRQHIST-------- 750

  Fly   898 VITSGTYDHLMPTYAVVDKKTAPPPGHGQYIQYNTLIPVSKMGA--YANQQQQLQQQPQQKTELS 960
             |.:.:...|:.|      .|||          |.....|.|.|  :||....|
Mosquito   751 -IDTNSPSRLLLT------TTAP----------NQTFIGSSMAAALHANHSSTL----------- 787

  Fly   961 YSELSAPLVSGPVGVQRMAPYCSATLGRPGRQAELKRAEPNIYSQVNV--MMDDEILADLQAATA 1023
                               .||:...|.|  ||.      |..:.|::  |......|.....|.
Mosquito   788 -------------------GYCTLRNGTP--QAS------NSITNVSMCHMPSTFTTASHTTCTL 825

  Fly  1024 SGRSYVAGAVVDNVGG-APNLYVQGYATRIDLAHHPMPMYSTSPMFGTNSTITGVTMSHPSQLAT 1087
            ......||......|. .||            ||| .|.|..:.....|.|...||.:..
Mosquito   826 PRHPVTAGTGAVGPGPLTPN------------AHH-WPSYGGTIAGVRNITAISVTSNQG----- 872

  Fly  1088 FSPTPPPP 1095
             ||.||||
Mosquito   873 -SPAPPPP 879

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
side-VIII	NP_001097382.2	IG_like	60..166	CDD:214653	45/106 (42%)
		Ig strand B	69..72	CDD:409353	1/2 (50%)
		Ig strand C	85..89	CDD:409353	2/3 (67%)
		Ig strand E	131..135	CDD:409353	2/3 (67%)
		Ig strand F	145..150	CDD:409353	3/4 (75%)
		Ig	189..273	CDD:472250	30/83 (36%)
		Ig strand B	197..201	CDD:409353	1/3 (33%)
		Ig strand C	211..215	CDD:409353	2/3 (67%)
		Ig strand E	237..241	CDD:409353	0/3 (0%)
		Ig strand F	252..257	CDD:409353	2/4 (50%)
		Ig strand G	267..270	CDD:409353	0/2 (0%)
		Ig	290..373	CDD:472250	34/82 (41%)
		Ig strand B	296..300	CDD:409353	2/3 (67%)
		Ig strand C	310..314	CDD:409353	2/3 (67%)
		Ig strand F	350..355	CDD:409353	3/4 (75%)
		Ig strand G	366..369	CDD:409353	2/2 (100%)
		Ig_3	377..456	CDD:464046	38/78 (49%)
side-VII	XP_061497694.1	None