DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11192 and Prss36

DIOPT Version :9

Sequence 1:	NP_611479.2	Gene:	CG11192 / 37309	FlyBaseID:	FBgn0034507	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	XP_017167884.1	Gene:	Prss36 / 77613	MGIID:	1924863	Length:	863	Species:	Mus musculus

Alignment Length:	273	Identity:	92/273 - (33%)
Similarity:	130/273 - (47%)	Gaps:	38/273 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 TPTPGD------------GRIVGGEVATIQEFPYQVSVQLQGRHICGGAIIGIDTVLTAAHCFE- 71
            :||.|:            .|||||..|....:|:|||:...|.|||||::|....||:|||||.
Mouse    28 SPTQGEFEDLDCGRPEPSSRIVGGSDAHPGTWPWQVSLHQGGGHICGGSLIAPSWVLSAAHCFVT 92

  Fly    72 ----DPWSSADYTVRVGSSEHE-SGGHVLSLRRVIAHGDYNPQSHDNDLALLILNGQLNFTEHLQ 131
                :|.......:.|.|.:.. .|.|:.|:..::...:|:......|||||.|.........::
Mouse    93 NGTLEPADELSVLLGVHSQDGPLEGAHMRSVATILIPDNYSTVELGADLALLRLASPAKLGPSVR 157

  Fly   132 PVPLAALADPPTADTRLQVSGWGFQAEESAVSGEVGVSPQLRFVDVDLVESNQCRRAYS------ 190
            ||.|...:......|....:||| ..:|:.   .:.:...|:.|::.|:....|:..||
Mouse   158 PVCLPRASHLFAHGTACWATGWG-DVQEAV---PLPLPWVLQEVELRLLGEAACQCLYSRPGPFN 218

  Fly   191 ---QVLPITRRMICAARPG--RDSCQGDSGGPLVGYAAEEGPARLYGIVSWGLGCANPNFPGVYT 250
               |:||   .|:||..|.  ||:||||||||||  ..:.|...|.||.|:|.||...|.|||:|
Mouse   219 LTFQLLP---GMLCAGYPAGRRDTCQGDSGGPLV--CEDGGRWFLAGITSFGFGCGRRNRPGVFT 278

  Fly   251 NVAAFRSWIDEQL 263
            .||.:.|||.|.:
Mouse   279 AVAPYESWIREHV 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11192	NP_611479.2	Tryp_SPc	27..259	CDD:214473	86/248 (35%)
CG11192	NP_611479.2	Tryp_SPc	28..262	CDD:238113	87/250 (35%)
Prss36	XP_017167884.1	Tryp_SPc	48..290	CDD:238113	87/250 (35%)
		Tryp_SPc	331..532	CDD:389826
		Tryp_SPc	607..789	CDD:389826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839478
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030