DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11192 and KLK15

DIOPT Version :9

Sequence 1:NP_611479.2 Gene:CG11192 / 37309 FlyBaseID:FBgn0034507 Length:279 Species:Drosophila melanogaster
Sequence 2:NP_059979.2 Gene:KLK15 / 55554 HGNCID:20453 Length:256 Species:Homo sapiens


Alignment Length:278 Identity:91/278 - (32%)
Similarity:130/278 - (46%) Gaps:49/278 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 WLMALVAYAGATPTPGDG-RIVGGEVATIQEFPYQVSVQLQGRHICGGAIIGIDTVLTAAHCFED 72
            ||:..:::..|:....|| :::.|:.......|:||::..:||..||.::|....||:||||   
Human     2 WLLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHC--- 63

  Fly    73 PWSSADYTVRVGSSEH-----ESGGHVLSLRRVIAHGDYNPQSHDNDLALLILNGQLNFTEHLQP 132
              .|....||:|  ||     :....:.:..|||.|..|..:||.||:.||.|         :||
Human    64 --QSRFMRVRLG--EHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRL---------VQP 115

  Fly   133 VPLAALADPPTADTRLQ-------VSGWGFQA-EESAVSG----EVGVSPQLRFVDVDLVESNQC 185
            ..|.....|....||..       |||||..: .|...:|    :|.:...|...::.::....|
Human   116 ARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSC 180

  Fly   186 RRAYSQVLPITRRMICAARPGR--DSCQGDSGGPLV--GYAAEEGPARLYGIVSWG-LGCANPNF 245
            .::|...|  |..|:||...||  :||:||||||||  |.        |.|||||| :.|.|...
Human   181 DKSYPGRL--TNTMVCAGAEGRGAESCEGDSGGPLVCGGI--------LQGIVSWGDVPCDNTTK 235

  Fly   246 PGVYTNVAAFRSWIDEQL 263
            |||||.|..:..||.|.:
Human   236 PGVYTKVCHYLEWIRETM 253

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11192NP_611479.2 Tryp_SPc 27..259 CDD:214473 83/253 (33%)
Tryp_SPc 28..262 CDD:238113 85/255 (33%)
KLK15NP_059979.2 Tryp_SPc 25..249 CDD:214473 83/249 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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