DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tapas and LCL3

DIOPT Version :9

Sequence 1:	NP_611475.3	Gene:	tapas / 37304	FlyBaseID:	FBgn0027529	Length:	1222	Species:	Drosophila melanogaster
Sequence 2:	NP_011430.1	Gene:	LCL3 / 852795	SGDID:	S000003053	Length:	274	Species:	Saccharomyces cerevisiae

Alignment Length:	187	Identity:	40/187 - (21%)
Similarity:	63/187 - (33%)	Gaps:	55/187 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   769 KTTPILVSHINDDGDLMVLL-----------RNDDLK---FVERSIAQTVADLGEQDRVSYSDLL 819
            |:..:.|..|...|..:.|:           |.:|:.   |.:..:...|..:|:.|..
Yeast    10 KSADVAVLSIILTGSTLTLIYTYKRYLTQFKRTNDIPRRIFRKHWLYGKVTSVGDGDNF------ 68

  Fly   820 HDRHIFVCDETVDGVKQWFRGRLVTRPLNPDEES------------FDVYYVDDGRQRKAHI--- 869
               |.|.....:.|...|.|.  |.:.:..|..:            |:..::..||..|:.|
Yeast    69 ---HFFHMPGGIRGGWGWLRP--VPQMIKNDSTAEKLVGDSRNMRFFNFNWITHGRSTKSKIQKA 128

  Fly   870 -SNIYRLEA---NNRALATFPPQAIPVRL--HDVPEIGGHMLHRLRGLIPWRTEALL 920
             |...:|..   |.:.|.|     ||:||  .|.||    ..|......|:..|||:
Yeast   129 KSQFLKLNVPYKNRKNLPT-----IPIRLCGIDAPE----RAHFGNPAQPFGNEALI 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tapas	NP_611475.3	LOTUS_TDRD_OSKAR	7..92	CDD:193586
		TUDOR	563..673	CDD:278965
		TUDOR	766..896	CDD:278965	32/161 (20%)
		TUDOR	1032..1151	CDD:278965
		TUDOR	1087..1131	CDD:119391
LCL3	NP_011430.1	SNase	149..261	CDD:395448	11/32 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900