Protein Alignment tapas and Tdrd1

DIOPT Version :10

• Sequence 1: NP_611475.3
• Gene: tapas / 37304
• FlyBaseID: FBgn0027529
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: XP_006527536.1
• Gene: Tdrd1 / 83561
• MGIID: 1933218
• Length: 1173
• Species: Mus musculus
• Alignment Length: 1099
• Identity: 218/1099 - (19%)
• Similarity: 351/1099 - (31%)
• Gaps: 366/1099 - (33%)

  Fly   239 KAPVMNGHGP--RHVKVANGQDKHNDGKPPLRAILGNSASQ---RQQDTSTVYHSPESSFKRPRH 298
            ::||...:.|  |.....||..|:|       .:|.....|   .|:|:|.|..:|
Mouse    34 RSPVAQHNHPTFRLKSPENGNTKNN-------FLLCEQNKQYLASQEDSSVVSSNP--------- 82

  Fly   299 PRVMYPGHQRTTGVSVNHRLKVTPQSDAPTPAVAPITP-----PASPEYAQTTTAAKATYKEDIH 358
                         ..||..:..:.....|.|...|::|     .:.|...:|..::..|.::...
Mouse    83 -------------AVVNGEVGGSKGDRKPPPTGNPVSPLSLGNSSPPNQVKTKPSSNVTPEKSKK 134

  Fly   359 GGQ-GETGNVVTNPKVKVPLKFDPSLDPV--STLNFYCAANDFEKPAYNIFNKLRNLHCSVQIAG 420
            ..: .|....|.||.:     |: ||.|.  ||....|          .:|..||...|
Mouse   135 SHKLFENALSVNNPAL-----FN-SLGPPLRSTTCHRC----------GLFGSLRCSQC------ 177

  Fly   421 DVYSSYPQEFTDKETAYQRTAQIAIQRIMHAQSHQKLSACTFSDVEFIDGLYKELLKHPHGILGH 485
                        |:|.|..|   |.|| ....||..:.......:                   :
Mouse   178 ------------KQTYYCST---ACQR-RDWSSHSTICRPVQQSL-------------------N 207

  Fly   486 KLEDWYGSTFRQHLPSHWYDLIVKSNKIRVEHGIDPRIILFANDPGSSEPDRTSITTLPQMVLPW 550
            ||||       ...|.....:.|||.::....|:...|        ::..:|...:.|..:.|..
Mouse   208 KLED-------NKSPFETKAIEVKSEQVDCPPGVTKEI--------TAGAERVMFSDLRSLQLKK 257

  Fly   551 QSSEGGS-----HDWNMFISFCDSTKIVWARMIDQIANFEELTKHIGRQMESPHFRQKVSKPYAQ 610
            .....|:     |..|.:|....|         :.:.|..:|:..:                  :
Mouse   258 TMEIKGTVTEFKHPSNFYIQLYSS---------EVLENMNQLSTSL------------------K 295

  Fly   611 EVYLVEMP-DG------------------WNRVRAISVDEETRSGRYHFIDFGDVAMFHSE---- 652
            |.|...:| ||                  |||....:||...|.....:||:|:..|...:
Mouse   296 ETYANVVPEDGYLPVKGEVCVAKYTVDQTWNRAIVQAVDVLQRKAHVLYIDYGNEEMIPIDSVHP 360

  Fly   653 -----DLFHCPPQFL-----------------------ALPAQAVCLSMYALDKFEDHPHALQVL 689
                 |||  ||..:                       ||..:..| |:..:|..|:     :||
Mouse   361 LSRGLDLF--PPSAIKCCVSGVIPTAGEWSEGCVAAVKALLFEQFC-SVKVMDILEE-----EVL 417

  Fly   690 T-----------KELDGQTVVAHVLTTEKQFLELGGSAQGVVENGKRRACLVATLYDTSTAEDI- 742
            |           |:||      |||      :|:|...:...::...::      .|.|..||:
Mouse   418 TCAVDLVLQSSGKQLD------HVL------VEMGYGVKPGEQSSTEQS------VDHSALEDVG 464

  Fly   743 ----------HLNDLVAKRITKCTPAPSLSDEKKIGKTTPILVSHINDDGDLMV--LLRNDDLKF 795
                      ..|.|:.|.:|           ..:|.....:|:||....|...  |.....|..
Mouse   465 RVTVESKIVTDRNALIPKVLT-----------LNVGDEFCGVVAHIQTPEDFFCQQLQSGHKLAE 518

  Fly   796 VERSIAQTVADLGEQDRVSYSDLLHDRHIFVCDETVDGVKQWFRGRLVTRPLNPDEESFDVYYVD 860
            ::.|:::....:  ..|..:...:.|    ||........||:|..::.   ...|||..|.|||
Mouse   519 LQESLSEYCGHV--IPRSDFYPTIGD----VCCAQFSEDDQWYRASVLA---YASEESVLVGYVD 574

  Fly   861 DGRQRKAHISNIYRLEANNRALATFPPQAIPVRLHDV-PEIGGHMLHRLRGLIPWRTEAL----- 919
            .|   ...|.::.||......|...|.||:...|..| |.:|           .|..||:
Mouse   575 YG---NFEILSLKRLCPIIPKLLDLPMQALNCVLAGVKPSLG-----------IWTPEAVCVMKE 625

  Fly   920 --------LKVVAMDGGKPLVNVFIREDPESMYMCVNIGLRLELEMASSIHPEKYDHTLLSSNVQ 976
                    ::||.|.|.:.||.:                  ::..:|..:...|   .|:.|...
Mouse   626 MVQNRMVTVRVVGMLGTRALVEL------------------IDKSVAPHVSASK---ALIDSGFA 669

  Fly   977 LPRRGSFSSVFSNQSSSSDLVATTPPVTPEKKPSARSTGSTFSSLMLKDYEAIP------AVGAY 1035
            :..:.......|..::|..|....|.                        ||:.      .|...
Mouse   670 IKEKDVADKGSSMHTASVPLAIEGPA------------------------EALEWTWVEFTVDET 710

  Fly  1036 FEVRVALSVNPGHFAVQPYKYY------NQLQTLMKNLQEHCQKTAAKGVQPSQLAIGEAYAAPD 1094
            .:|.|.:..:||.|    |.::      .:|..|.::|.::|.:....|.:..   ||....|..
Mouse   711 VDVVVCMMYSPGEF----YCHFLKDDALEKLDDLNQSLADYCAQKPPNGFKAE---IGRPCCAFF 768

  Fly  1095 S-EGVYHRVSIHKIYDE-IIHVRFVDVGDDGVIACDQLKTLNPELRKLPKMALPAQLYGIQLTDV 1157
            | :|.::|..:.:|... .:.|.|||.|:...:..|||:.:.|:...||...:...|..||..:.
Mouse   769 SGDGNWYRALVKEILPSGNVKVHFVDYGNVEEVTTDQLQAILPQFLLLPFQGMQCWLVDIQPPNK 833

  Fly  1158 VWSKENCVRFRELSLGQKFIGIVRRMTKQKDGGRALCLELVDTSTPKDIKLHEILINEK 1216
            .|:||...||:...:|.|....|..:|....|     :||.|.|||....:.::||.|:
Mouse   834 HWTKEATARFQACVVGLKLQARVVEITANGVG-----VELTDLSTPYPKIISDVLIREQ 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tapas	NP_611475.3	LOTUS_TDRD_OSKAR	7..92	CDD:193586
		TUDOR	563..673	CDD:425754	27/160 (17%)
		TUDOR	769..896	CDD:425754	30/128 (23%)
		TUDOR	1034..1151	CDD:425754	30/124 (24%)
Tdrd1	XP_006527536.1	zf-MYND	163..199	CDD:460312	14/67 (21%)
		Tudor_TDRD1_rpt1	263..392	CDD:410479	27/157 (17%)
		Tudor_TDRD1_rpt2	513..594	CDD:410480	20/92 (22%)
		TUDOR	716..825	CDD:425754	27/115 (23%)
		Tudor_SF	937..1052	CDD:470623