Protein Alignment tapas and Rnf17

DIOPT Version :10

• Sequence 1: NP_611475.3
• Gene: tapas / 37304
• FlyBaseID: FBgn0027529
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: NP_001028215.1
• Gene: Rnf17 / 30054
• MGIID: 1353419
• Length: 1640
• Species: Mus musculus
• Alignment Length: 1165
• Identity: 230/1165 - (19%)
• Similarity: 389/1165 - (33%)
• Gaps: 351/1165 - (30%)

  Fly   211 EVAREKQKEKETRDRAVTETIFVTIENKK--APVMNGHGPRHVKVANGQDKHNDGK--------- 264
            |..:..||:...|.....: ::.::|.||  |.|:....|.....|...|:|.:||
Mouse   314 EDGQNVQKKFNNRKELCCD-VYSSLEKKKVDAAVLTDETPEPPLQAEAPDRHLEGKKKQPTKEMV 377

  Fly   265 ----PPLRAI---LGNSASQRQQDTSTVYHSPESSFKRPRHPRVMYPGHQRTTGVSVNHRLKVTP 322
                |...|:   ||:|.....::  .:..:.||.|.........||              |..|
Mouse   378 VVTSPKTIAVLPQLGSSPDVIIEE--IIEENLESCFTDDPIETSGYP--------------KKPP 426

  Fly   323 QSDAPTPA-----------VAPITPPAS---PEYAQTTTAAKATYKEDIHGGQGETGNVVTNPKV 373
            |.:...|.           |:.:..|..   .:|:|...|                  .:...|:
Mouse   427 QKEQSAPVGSKAGCPELVFVSHVIHPCHFYVRKYSQIKDA------------------TILEKKM 473

  Fly   374 KVPLKFDPSLDPVSTLNFYCAANDFEKPAYN-----------IFNKLRNLH--CSVQIAGDVYSS 425
            |........|||...|..  .|..|.....|           |.:|.:|:.  ||
Mouse   474 KQVCNRSLHLDPSDILEL--GARIFVNSIKNRMWCRGIITEIIPSKTKNIRKPCS---------- 526

  Fly   426 YPQEFTDKETAYQRTAQIAIQRIM-------------------HAQSHQKLSACTFSDVEFI--- 468
             |.:|:        ..:|::.:|.                   ....|......|.||...:
Mouse   527 -PTKFS--------VCEISLIQIFMVDFGNSEVLIITGVGDTHEGPEHDGEQHITLSDFCLLLMK 582

  Fly   469 -DGLYKELLKH-PHGILGH--KLEDW--YGST--FRQHLPSHWYDLIVK---------------- 509
             :...:||||. ||  |.|  .|:|.  |.||  :.:.....:..::.|
Mouse   583 SEPYSEELLKDIPH--LAHLCSLKDIVPYNSTEGWEKEAKVEFLKMVNKKAVLMKVFGEEDDVLI 645

  Fly   510 -------SNKIRVEHGIDPRIILF--------ANDPGSSEPDRTSITTLPQMVLPWQSSEGGSHD 559
                   :|||..:..:..|..|.        :..|.|.....|::...|. :||.:.:|
Mouse   646 VDLQKPPTNKISSDMPVSLRDALVFMELARFRSQSPRSHSEKNTTLCYHPP-ILPEEMTE----- 704

  Fly   560 WNMFISFCDSTKIVWARMIDQIANFEELTKHI--------GRQMESPHFRQKVSKPYAQEVYLVE 616
            .::.:...:|....:.::::.: :|..|.|.|        |..:|       :..|...:..:.:
Mouse   705 VSVMVCHINSPTDFYLQLMENL-DFLSLLKTIEEFYKGEDGENLE-------ILCPLQNQACVAK 761

  Fly   617 MPDG-WNRVRAISVDEETRSGRYHFIDFGDVAMFHSEDLFHCPPQFLALPAQAV-CLSMY----- 674
            ..|| |.|.:.|.:... |.....::|||:.|....:|:.....:||..|.:|: |...|
Mouse   762 FEDGIWYRAKVIGLPGH-REVEVKYVDFGNTAKITLKDMRKIKDEFLEPPEKAIKCKLAYVEPSK 825

  Fly   675 -------ALDKFEDHPHALQVLTKELDGQTVVAHVLTTEKQFLELGGSAQGVVENGKRRACLVAT 732
                   |.:|||:                      .|:.:|:..  |...::||.    .|:..
Mouse   826 KSQWSKKAKEKFEE----------------------KTQDKFVTC--SVIKILENN----VLLVE 862

  Fly   733 LYDTST--AEDIHLND-LVAKRITKCTPAPSLSDEKK----IGKTTP--ILVSHINDDGDLMV-- 786
            |:|:..  ...:.:|| ||.:.:.......:|.|..|    :...:|  |:.|.||:...|.|
Mouse   863 LFDSRAPGKSAVSINDQLVKEGLASYEAGYTLKDNSKKHLEVWDPSPEEIITSEINNLSPLSVKS 927

  Fly   787 -------LLRNDDLK------------FVERSIAQTVADLGEQDRVSYSDLLH----------DR 822
                   .|.|.:|.            :|:..:.:.:.:..|:..|:..:  |          |.
Mouse   928 LPNENFQSLYNKELPVNICNVISPEKIYVQWLLTENLLNSLEEKMVAAYE--HSEWKPVKWECDM 990

  Fly   823 HIFVCDETVDGVKQWFRG---RLVTRPLNPDEESFDVYYVDDGRQRKAHISNIYRLEANNRALAT 884
            |   |...|....||.||   |:||      ::..:|...|.|.:...:|..:..|:.|   |.|
Mouse   991 H---CAVKVPAKNQWRRGQILRMVT------DKLVEVLLYDVGVELVVNIHCLRELQEN---LKT 1043

  Fly   885 FPPQAIPVRLHDVPEIGGH-----------MLHRLRGLIPWRTEALLKVVAMDGGK--PL-VNVF 935
            ....::...|.|:...||.           .||        .|.|:..::..:...  || |.:|
Mouse  1044 MGRLSLECSLVDIRPTGGSDKWTATACDCLSLH--------LTGAIATIILQESNTTWPLPVKIF 1100

  Fly   936 IRED-----PESMYMCVNIGLRL---ELEMASSIH-PEKYDHTLLSSNVQLPRRGS-----FSSV 986
            .|::     ..|.|: :..||.|   .:..:|:.| |||      |..:.|.:..|     |...
Mouse  1101 CRDEKGERVDVSKYL-IKKGLALRERRVSKSSNSHSPEK------SLEIPLEQGDSVVTKCFKIN 1158

  Fly   987 FSNQSSSSDLV-ATTPPVTPEKKPSARSTGSTFSSLMLKDYE--AIPAVGAYFEVRVALSVNPGH 1048
            |......:|.| ....|.:..||..:||||.         |.  |:|...: ||..|....:.|.
Mouse  1159 FDTNKKIADKVNEHKVPDSKGKKSESRSTGC---------YRPPAVPNTSS-FEAIVTCIGDDGT 1213

  Fly  1049 FAVQPYKYYNQLQTLMKNLQEHCQKTAAKGVQPSQLAIGEAYAAPDSEGVYHRVSIHKIYDEIIH 1113
            ..|.|.....:|..:|..:|.:.:....  ::|.....||..|...|:.:::|..:.::....|.
Mouse  1214 IFVVPKLSEFELIKMMDEIQSNLKCLGL--LEPYSWKKGEPCAVRGSDTLWYRGKVMEVVGGTIR 1276

  Fly  1114 VRFVDVG-DDGVIACDQLKTLNPEL--RKLPKMALPAQLYGIQLTDVVWSKENCVRFREL 1170
            |:::|.| .:.:..|.    |.|.|  ...|:..:|.|||........|..:.....:||
Mouse  1277 VQYLDHGFTEKIPQCH----LYPILLYPDTPQFCIPCQLYQTLPVGNTWQPDAIELLQEL 1332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tapas	NP_611475.3	LOTUS_TDRD_OSKAR	7..92	CDD:193586
		TUDOR	563..673	CDD:425754	24/119 (20%)
		TUDOR	769..896	CDD:425754	34/162 (21%)
		TUDOR	1034..1151	CDD:425754	27/119 (23%)
Rnf17	NP_001028215.1	PRK03918	87..>273	CDD:235175
		CC_brat-like	158..>242	CDD:475168
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	348..376		6/27 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	413..435		6/35 (17%)
		Tudor_TDRD4_rpt1	490..565	CDD:410485	12/95 (13%)
		Tudor_TDRD4_rpt2	728..823	CDD:410486	24/102 (24%)
		Tudor_TDRD4_rpt3	968..1049	CDD:410487	22/94 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1170..1191		7/29 (24%)
		Tudor_TDRD4_rpt4	1247..1314	CDD:410488	18/70 (26%)
		Tudor_TDRD4_rpt5	1494..1598	CDD:410489