DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tapas and si:ch211-189e2.3

DIOPT Version :9

Sequence 1:	NP_611475.3	Gene:	tapas / 37304	FlyBaseID:	FBgn0027529	Length:	1222	Species:	Drosophila melanogaster
Sequence 2:	XP_021328732.1	Gene:	si:ch211-189e2.3 / 100536102	ZFINID:	ZDB-GENE-030131-6454	Length:	1813	Species:	Danio rerio

Alignment Length:	778	Identity:	154/778 - (19%)
Similarity:	274/778 - (35%)	Gaps:	216/778 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   551 QSSEGG---------SHDWNMFISFCDSTKIVWARMIDQIANFEELTKHIGRQMESPHFRQ---- 602
            ||::||         |...:.::......| |.|:|...|...|.:.:..|      ||.|
Zfish   483 QSTKGGYTLNAATTSSLQADAYVDVPPKIK-VGAKMKLHITCVESVNQFYG------HFAQNTDA 540

  Fly   603 --KVSKPYAQ---------------EVYLVEMPDG-WNRVRAISVDEETRSGRYHFIDFGDVAMF 649
              |::|...|               .:.|.:..|| |:|.:..||..:.   ...|:|:||:.:.
Zfish   541 VAKMTKDIQQLCRKRPQAKFSISPKMMCLAKFSDGQWHRGQIESVHPKI---LVQFVDYGDLVVV 602

  Fly   650 HSEDLFHCPPQ---FLALPAQAVCLSM-----------------YALD----------------- 677
            ...|:...||.   ..:||.|||...:                 ||.|
Zfish   603 DKSDILPFPPNANAIASLPIQAVQFELFNVALPEPCELNEWFKNYATDCMFNVVVKLNSSGKLSV 667

  Fly   678 KFEDHPHALQVLTKELDGQTVVAHVLTTE--------------KQFLELGGSAQGVVENGKRRAC 728
            :..|....|.:..|:|..:|.....:.|:              .:|.|:..|.....:..:|...
Zfish   668 EMYDDKTNLNLKIKDLWSKTKRNESINTKGIVKTRGFKETSEGMEFREVRNSFSTTSQAHERTLK 732

  Fly   729 LV-----------ATLYDTSTAEDIHLNDLVAKRI---TKCTPAPSLSDEKKIGKTTPILVSHIN 779
            .|           ||.|..:|..:....:::.:::   .|.|..|..:.:  :|..:.:.|||.|
Zfish   733 PVGQARTEQNFQSATGYSNATGNNRAWPNVLQQQVMAYPKLTELPLRTID--VGYVSDVYVSHCN 795

  Fly   780 DDGDLMVLLRNDD---LKFVERSIAQTVADLGEQDRVSYSDLLHDRHIFVCDETVDGVKQWFRGR 841
            ...:..|.|..|:   ...:|:.....::||..:     .:||....:...:...||.  ::|..
Zfish   796 SPSNFFVQLTTDEDEIFSLIEKLNCTLISDLQVE-----LNLLQSDDLVKAEYPADGA--YYRAV 853

  Fly   842 LVTRPLNPDEESFDVYYVDDGRQRKAHISNIYRLEANNRALATFPPQAIPVRLHDVPEIGGHMLH 906
            :.::    ......|.::|.|.:.....:.|.:|:  .:.|:| |..:|...|.|         .
Zfish   854 VKSK----KNGMVQVQFIDFGNEVTLLPTKIKQLD--KQFLST-PRLSIQCMLED---------G 902

  Fly   907 RLRGLIPWRTEALL---KVVAMDGGKPLVNVFIREDPESMYMCVNIGLRLELEMASSIHPEKYDH 968
            :.||...|..|.::   :....:|.|.:...||:||.    .|..:.|.         |.|
Zfish   903 KRRGKRDWTQEEIMTFKEAAGENGEKKIQCKFIQEDA----TCWLVSLE---------HQE---- 950

  Fly   969 TLLSSNVQLPRRGSFSSVFSNQSSSSDL--VATTPPVTPEKKPSARSTGSTFSSLMLKDYEAIPA 1031
                        |.| :|.|:..|.|.:  :..|.|:|.:|                      ||
Zfish   951 ------------GWF-TVKSDAQSESQVHCIKNTQPLTFKK----------------------PA 980

  Fly  1032 V--GAYFEVRVALSVNPGHFAVQPYKYYNQLQTLMKNLQEHCQKTAAKGVQPSQLAIGEAYAAPD 1094
            |  |...|...:..|.|.:|..| :|....|..:....||....:..|.:||.||..|....|..
Zfish   981 VTPGQTVEAYASSIVGPNYFWCQ-FKNSEILDKISLLAQEIGNSSHTKAIQPDQLRQGGICLARF 1044

  Fly  1095 SEGVYHRVSIHKIYDEIIHVRFVDVGDDGVIACDQLKTLNPELRKLPKMALPAQLYGIQLTDVVW 1159
            |:.:::|..:...::: :.|.|:|.|::..|..:.:|.|..:|.:.|..|...||..:...:..|
Zfish  1045 SDQLWYRAQVINTHEK-VSVLFIDYGNESEIDFNSIKALPTKLLESPPQAFLCQLQVLGSVEGTW 1108

  Fly  1160 SKENCVRFRELSLGQKFIGIVRRMTKQKDGGRALCLELVDTSTPKD-------IKLHEILINE 1215
            |.....:|.|:.:.:..     ::|.|         .:|.|..|..       ::..|:::|:
Zfish  1109 SDSAADKFFEILVDEPL-----KVTVQ---------NMVVTPNPTMCPQFSVLVECKELIVND 1157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tapas	NP_611475.3	LOTUS_TDRD_OSKAR	7..92	CDD:193586
		TUDOR	563..673	CDD:278965	32/134 (24%)
		TUDOR	766..896	CDD:278965	26/132 (20%)
		TUDOR	1032..1151	CDD:278965	32/120 (27%)
		TUDOR	1087..1131	CDD:119391	9/43 (21%)
si:ch211-189e2.3	XP_021328732.1	TUDOR	<65..128	CDD:306940
		TUDOR	247..360	CDD:306940
		TUDOR	511..631	CDD:306940	32/129 (25%)
		TUDOR	787..899	CDD:306940	24/125 (19%)
		TUDOR	983..1099	CDD:306940	30/117 (26%)
		TUDOR	1245..1364	CDD:306940
		TUDOR	1453..1572	CDD:306940
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22948
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010