Protein Alignment tapas and TDRD15

DIOPT Version :10

• Sequence 1: NP_611475.3
• Gene: tapas / 37304
• FlyBaseID: FBgn0027529
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: NP_001293066.1
• Gene: TDRD15 / 100129278
• HGNCID: 45037
• Length: 1934
• Species: Homo sapiens
• Alignment Length: 719
• Identity: 135/719 - (18%)
• Similarity: 248/719 - (34%)
• Gaps: 217/719 - (30%)

  Fly   577 MIDQIANFEELTKHIGRQMESPHFRQKVSKPY--AQEVYLVEMPDGWNRVRAISVDEETRSGRYH 639
            :::||.|:..:           |     |.||  .|...:.:....|  .||..:.:.::.....
Human   785 LMEQIQNYYSI-----------H-----SDPYEIGQTACVAKYSGKW--CRAAVLTQVSKEVDIV 831

  Fly   640 FIDFGDVAMFHSEDLFHCPPQFLALPAQA--VCLSMYALDKFEDHPHALQVLTKELDGQTVVAHV 702
            |:|:|.......|||....|:||.|.:||  .||:           |.::.::.:|        .
Human   832 FVDYGYQKRVLIEDLCAINPRFLLLESQAFRCCLN-----------HFIEPVSCKL--------F 877

  Fly   703 LTTEKQFLELG---GSAQGVVENGKRRACLVAT--------LYDT-------STAEDIHLNDLVA 749
            ..|.|.|.:|.   .|::|::      .|::..        ||:.       ::|::..:|...|
Human   878 SWTRKAFRDLWNFISSSRGLL------TCIIYALVIIHPNHLYNLVDLQSSFTSAKEFLMNRGSA 936

  Fly   750 KRITKCTPAPSL---------SDEKKIGKTTPILVSHINDDGDLMVLL--RNDDLKFVERSIAQT 803
            :.||.....|||         |...:||....:.:|||.........|  .|.||:.:|..|.::
Human   937 QYITLSETFPSLFSLYSYCYSSFNIQIGSEEEVYISHIYSPQKFYCQLGRNNKDLEMIETKITES 1001

  Fly   804 VADLGEQDRVSYSDLLHDRHIFVCDETVDGVKQWFRGRLVTRPLNPDEESFDVYYVDDGRQRKAH 868
            |   ..|:...|..  :...:.:.....||:..    |.:..|.:...| |.||:||.|.::...
Human  1002 V---NLQNFPKYDS--NKMRVCISKYVEDGLSY----RALAIPTDSSSE-FQVYFVDFGNKQLVG 1056

  Fly   869 ISNIYRLEANNRALATFPPQAIPVRLHDVPEIGGHMLHRLRGLIP-----WRTEALLKVVAMDGG 928
            .:.:..:.|....|...|.|||...|.|:.::.          ||     |..:..|       |
Human  1057 ENMLRAISAQFPELLFTPMQAIKCFLSDLRDVD----------IPAEISSWFKDNFL-------G 1104

  Fly   929 KPLVNVFIREDPE----------SMYMCVNIGLRLE------------LEMASSIHPEK------ 965
            :.|..:.:.::.:          |.|:...|.:.|.            :|.::.|:..|
Human  1105 RSLKAIILSQESDGQLGIELYDGSQYINEKIKVLLHAYGKRHCDQACCMEKSNKINENKRFTTSL 1169

  Fly   966 -------YDHTLLSSNVQLPRRGSFSSVFSNQSSSSDLVAT---TPPVTPEKKPSARSTGSTFSS 1020
                   |.|.:::.    |...::|....:|......:..   .|.|..:.:|.:::...|..:
Human  1170 KGKTGNNYRHNVINK----PSPVTYSERKIDQLMHPKNIHARFLKPSVCYKMEPVSKNKMKTSLN 1230

  Fly  1021 LMLKDYEAIPAVGAYFEVR---------------------------------------------- 1039
            ..||..:.:|......|.|
Human  1231 DGLKGIKIVPGAAHILENRRVGQKSVKVVSQSFIRALNQTTSQNPYDLIRPQIKDLPQPQIYLNA 1295

  Fly  1040 -----VALSVNPGHFAVQPYKYYNQLQTLMKNLQEHCQKTA-----AKGVQPSQLAIGEAYAAPD 1094
                 |:...||.:|.:|    ..:.::::..|.:....||     .|.|:|   .:|:...|..
Human  1296 KVKGYVSNISNPANFHIQ----LAENESVIIRLADALNATARRLRERKSVKP---LVGDLVVAEY 1353

  Fly  1095 S-EGVYHRVSIHKIY-DEIIHVRFVDVGDDGVIACDQLKTLNPELRKLPKMALPAQLYGIQLT-- 1155
            | :...:|..|.||. .....|.|:|.|:..::...::..|..|...:|::.:.|.|.|::..
Human  1354 SGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKWNEP 1418

  Fly  1156 DVVW 1159
            |.:|
Human  1419 DEIW 1422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tapas	NP_611475.3	LOTUS_TDRD_OSKAR	7..92	CDD:193586
		TUDOR	563..673	CDD:425754	25/99 (25%)
		TUDOR	769..896	CDD:425754	30/128 (23%)
		TUDOR	1034..1151	CDD:425754	29/174 (17%)
TDRD15	NP_001293066.1	Tudor_TDRD15_rpt1	14..160	CDD:410507
		Tudor_TDRD15_rpt2	239..358	CDD:410508
		Tudor_TDRD15_rpt3	478..618	CDD:410509
		Tudor_TDRD15_rpt4	747..868	CDD:410510	25/111 (23%)
		Tudor_TDRD15_rpt5	956..1082	CDD:410511	32/135 (24%)
		Tudor_TDRD15_rpt6	1306..1413	CDD:410512	26/113 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1490..1510
		Tudor_TDRD15_rpt7	1526..1678	CDD:410513
		TUDOR	1740..1852	CDD:425754