Protein Alignment tapas and Tdrd7

DIOPT Version :10

• Sequence 1: NP_611475.3
• Gene: tapas / 37304
• FlyBaseID: FBgn0027529
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: NP_001277404.1
• Gene: Tdrd7 / 100121
• MGIID: 2140279
• Length: 1119
• Species: Mus musculus
• Alignment Length: 1318
• Identity: 251/1318 - (19%)
• Similarity: 463/1318 - (35%)
• Gaps: 360/1318 - (27%)

  Fly     8 EYVAKVVRALITSAKPPVTLRSIVADYMEIEGEPIPFRRLGYSNDQELLKDSN---QFNFHQSGN 69
            :.|:|::||::.|.|..:.|..:..:|..:.|:.|||::|||...:..|:...   :....:||
Mouse    38 DLVSKMLRAVLQSHKNGIVLPRLQGEYRSLTGDWIPFKQLGYPTLEAYLRSVPAVVRIEASRSG- 101

  Fly    70 QVFITAKYNANTEHIVRMVRQQKTSK---------STSLSKPTPIAQKPKPIAQKHTHGNKYHYQ 125
            ::...|.....|..|.::|.:|:|||         ...:.|..|...:.||.|..
Mouse   102 EIVCYAVACTETARIAQLVARQRTSKRKIGRQINCQMRVKKAMPFFLEGKPKATL---------- 156

  Fly   126 QRNKQPNHQPDQEIGRAAKCENQAIAEHKQDLTGIITQELFESFNNIQGPFSENLQVFNKNPEYI 190
               :||....|..|.|.   .|.|:...:....|:........:.:.  |...:..: :.|..:.
Mouse   157 ---RQPGFASDYSISRK---PNSALLRDRGSALGVKADVDMPPYPDT--PVQRHASM-SANSRFS 212

  Fly   191 TRRKKELKKEDDLDRG---QITKEVAREKQKEKETRDRAVTETIFVTIENKKAPVMNGHGPRHVK 252
            .:.......:..:.|.   ::...:.:..:|...|...:.|        ||...|.|       :
Mouse   213 PKSSLPASFQTHISRACPTEVNDNLNQTVEKPNITPPASYT--------NKMDEVQN-------R 262

  Fly   253 VANGQDKHNDG----------KPPLRAILGNSASQRQQDTSTVYHSPE-SSFKRP---RHPRVMY 303
            :....||||:|          |...:..|.....|:.:      |.|. .:.::|   ....::|
Mouse   263 IKEILDKHNNGIWISKLPHFYKEFYKEDLNQGVLQQFE------HWPHICTVEKPCGGGQDSLLY 321

  Fly   304 PGHQRTTGVSVNHRLK--VTPQSDAPTPAVAPITPPASPEYAQTTTAAKATYKEDIHGGQGETGN 366
            |..:       ...||  ..|:.:.|.|      |||
Mouse   322 PARR-------EQPLKSDQDPEKELPPP------PPA---------------------------- 345

  Fly   367 VVTNPKVKVPLKFDPSLDPVSTLNFYCAANDFEKPAYNIFNKLRNLHCSVQIAGDVYSSYPQEFT 431
                ||.:||.:..|::.|           |.::....:..|..        :|...|:.|:.|.
Mouse   346 ----PKQEVPSQGSPAVMP-----------DVKEKVAELLGKYS--------SGLWASALPKAFE 387

  Fly   432 D------KETAYQRTAQIAIQRIMHAQSHQKLSACTFSDVEFIDGLYKELLKHPHGILGHKLEDW 490
            |      .|.|.:..|.::             ..||   :.:|.|..::      .||..||.
Mouse   388 DMYKVKFPEDALKNLASLS-------------DVCT---INYISGNTQK------AILYAKLP-- 428

  Fly   491 YGSTFRQHLPSHWYDLIVK-----SNKIRVEHGIDPRIILFANDPGSSEPDRTSITTLPQMVLPW 550
                    ||:   |.|:|     .....::..|:...:....:...|..:.....|:|.:|:|.
Mouse   429 --------LPT---DKILKDEGQAQGDFDIKSMIEQEYLQIEKNMAESADEFLEDITVPPLVIPT 482

  Fly   551 QSSEGGSHDWNMFISFCDSTKIVWARMIDQIANFEELT-KHIGR------QMESPHFRQKVSK-P 607
            ::|.                    :.::.:::|..::. :::|:      ::.....::..|| |
Mouse   483 EASP--------------------SVLVVELSNTNDVVIRYVGKDYSAAQELMEDEMKEFYSKNP 527

  Fly   608 YAQEVYLVEM---------PDGWNRVRAISVDEETRSGRYHFIDFGDVAMFHSEDLFHCPPQFLA 663
            ....:..|.:         .|.|.|.:.||.||  ...:..::|:|..........:...|:|.:
Mouse   528 RVTPIQTVHVGQLLAVNAEEDAWLRAQIISTDE--NKIKVCYVDYGFCENIEKSKAYRLNPRFCS 590

  Fly   664 LPAQAVCLSMYALDKFEDHPHALQVLTKELDGQTVVAHVLTTEKQFLELGGSAQGVVENGKRRAC 728
            |..||....:..|:...|.|..::.:.....|:.....:|  :|..:.|
Mouse   591 LSFQATKCKLAGLEVLNDDPDLVKAVESLTCGKIFAVEIL--DKSDVPL---------------- 637

  Fly   729 LVATLYDTSTAEDIHLNDLVAKRITKCTPAPSLSDEKKI-GKTTPILVSHINDDGDLMVLLRNDD 792
              ..|||||..:||::|....|.|  |.  .||....:: ...|.:.|::|..||.|...:....
Mouse   638 --VVLYDTSGEDDININATCLKAI--CD--RSLQVHLQVDAMYTNVKVTNICSDGTLYCQVPCKG 696

  Fly   793 LKFVERSIAQTVADLGEQDRVSYSDLLHDRH----------------IFVCDETVDGVKQWFRGR 841
            |..:...:.:|            .|..|.:|                :|.|.      .:|.|..
Mouse   697 LNKLNDLLHKT------------EDYFHCKHMTSEYFISLPFCGKICLFHCK------GKWLRVE 743

  Fly   842 LVTRPLNPDEESFDVYYVDDGRQRKAHISNIYRLEAN-NRALATFPPQAIPVRLHDVPEIGGHML 905
            :..   .....:.||.::|.|......:|.:..:... .:.:...|||||...|.|:|:..|
Mouse   744 ITN---VHSSRALDVQFLDSGNSTSVKVSELREIPPRFLQEMLAIPPQAIKCCLADLPQSIG--- 802

  Fly   906 HRLRGLIPWRTEALL--------------KVVAMDGGKPLVNVFIREDPESMYMCVNIGLRLELE 956
                   .|..:|:|              ||..||..|.:..|::
Mouse   803 -------MWTPDAVLWLRDSVLNCSDCSIKVTKMDETKGVAYVYL-------------------- 840

  Fly   957 MASSIHPEKYDHTLLSSNVQLP-------RRGSFSSVFSNQSSS-SDLVATTP-PVTPEK----- 1007
                ..|..:.....|.|.|:.       ::..|.|..|..:|| .:....|| |.:|.:
Mouse   841 ----FTPNNFPDPHRSINRQITNADLWKHQKDVFLSAVSTAASSPGNRNGGTPAPGSPAESLRKS 901

  Fly  1008 -----KPSARSTGSTFSSLMLKDYEAIPAVGAYFEVRVALSVNPGHFAVQPYKYYNQLQTLMKNL 1067
                 |.|.....|:||...|.....:...|.:.:|.|.::.:||||.:||::..::|:.||:.:
Mouse   902 HPEVIKKSVLDHTSSFSLEELPPPVHLSRSGEHMDVYVPVACHPGHFVIQPWQEIHKLEVLMEEM 966

  Fly  1068 QEHCQKTAAKGVQPSQLAIGEAYAAPDSEGVYHRVSIHKIY-DEIIHVRFVDVGDDGVIACDQLK 1131
            ..:...:..:.:...:   .:.||| ..|..::||.:..|. :.::.|..:|.|...::...:::
Mouse   967 ILYYSVSEERHIAVER---DQVYAA-KVENKWYRVLLKGILTNGLVSVYELDYGKHELVNIRKVQ 1027

  Fly  1132 TLNPELRKLPKMALPAQLYGIQLTDVVWSKENCVRFRELSLGQKFIGIVRRMTKQKD-GGRALCL 1195
            .|....||||..|:.|||.|::.:.  ||:|..:.||.....:..:.:|:.:.:..: ..|.:.|
Mouse  1028 PLVDVFRKLPFQAVTAQLAGVKCSQ--WSEEASMVFRNHVEKKALVALVQTVVEHTNPWDRKVVL 1090

  Fly  1196 ELVDTSTP-KDIKLHEIL 1212
            .|||||.| .|..:|:.:
Mouse  1091 YLVDTSLPDTDTWIHDFM 1108

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tapas	NP_611475.3	LOTUS_TDRD_OSKAR	7..92	CDD:193586	22/86 (26%)
		TUDOR	563..673	CDD:425754	20/126 (16%)
		TUDOR	769..896	CDD:425754	26/143 (18%)
		TUDOR	1034..1151	CDD:425754	30/117 (26%)
Tdrd7	NP_001277404.1	LOTUS_1_TDRD7	38..124	CDD:193600	22/86 (26%)
		LOTUS_2_TDRD7	256..322	CDD:193587	13/78 (17%)
		LOTUS_3_TDRD7	361..425	CDD:193588	16/93 (17%)
		Tudor_SF	513..610	CDD:470623	20/98 (20%)
		Tudor_TDRD7_rpt2	674..813	CDD:410499	32/169 (19%)
		Tudor_TDRD7_rpt3	951..1041	CDD:410500	20/93 (22%)