Protein Alignment CG11200 and DHRS12

DIOPT Version :9

• Sequence 1: NP_001286630.1
• Gene: CG11200 / 37301
• FlyBaseID: FBgn0034500
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_001364858.1
• Gene: DHRS12 / 79758
• HGNCID: 25832
• Length: 320
• Species: Homo sapiens
• Alignment Length: 353
• Identity: 92/353 - (26%)
• Similarity: 153/353 - (43%)
• Gaps: 62/353 - (17%)

  Fly    20 FSKTTKEFPKSWFEWK-TEFRYQYLGIVGLVHDAQYKARDRVALYKQPDRIAVITGGNRGIGLRI 83
            |:|..:|:.||.:|.. .:|         :.||.:.:.         |.|:.::||||.|||...
Human    10 FAKGLREYTKSGYESACKDF---------VPHDLEVQI---------PGRVFLVTGGNSGIGKAT 56

  Fly    84 VEKLLACDMTVVMGVRDPKIAETAVASIVDLNATKGKLICEQLDVGDLKSVKAFAQLIKERYSKV 148
            ..::.....||.:..||...||.|...|:..:..: .:....:|:.|.|.:..|.:..|:.: |:
Human    57 ALEIAKRGGTVHLVCRDQAPAEDARGEIIRESGNQ-NIFLHIVDLSDPKQIWKFVENFKQEH-KL 119

  Fly   149 DLLLNNAGIMFAPFKLTADGYESHFAINFLGHFLLTHLLLPQLRAAGKEGRNSRIVNVSSCVNLI 213
            .:|:||||.|....:||.||.|.:||.|.||.::||..|:|.|.   || .:.|::.|||...|:
Human   120 HVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLE---KE-HDPRVITVSSGGMLV 180

  Fly   214 GRINYKDINGTKHYYPGT-AYSQSKLAQILFTRHLQTLLDAEKSH--VQVNVVHPGIVDTD---- 271
            .::|..|:...:..:.|| .|:|:|..|::.|...      .:.|  :..:.:|||..||.
Human   181 QKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERW------AQGHPAIHFSSMHPGWADTPDRNE 239

  Fly   272 ------LFEHSATTSVPIFKKLFF---KTPERGSRTVVFAAIDPSIEGQGGTYLSNGGKGPFHPD 327
                  :.|....:.:|.|.::..   |...:|.          |.......:.|.||:....||
Human   240 QELRKVVGEAQTASPLPRFLEIMMHEGKCQPQGH----------SSNDLEACWSSGGGEQNSLPD 294

  Fly   328 AKKPAKCEQLFQFS---CDLLKIQQYGN 352
              .|.:...|.|.:   |....:.:.||
Human   295 --WPHQLHDLRQLTWALCSSFLLYKQGN 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11200	NP_001286630.1	PRK06196	56..344	CDD:235736	81/306 (26%)
		NADB_Rossmann	67..338	CDD:304358	77/286 (27%)
DHRS12	NP_001364858.1	NADB_Rossmann	40..>235	CDD:419666	64/206 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810