Protein Alignment CG11200 and dhrs12

DIOPT Version :10

• Sequence 1: NP_611471.1
• Gene: CG11200 / 37301
• FlyBaseID: FBgn0034500
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_001072547.1
• Gene: dhrs12 / 780002
• XenbaseID: XB-GENE-5957085
• Length: 323
• Species: Xenopus tropicalis
• Alignment Length: 294
• Identity: 92/294 - (31%)
• Similarity: 142/294 - (48%)
• Gaps: 39/294 - (13%)

  Fly    20 FSKTTKEFPKSWFEWKTEFRYQYLGIVGLVHDAQYKARDRVALYKQPDRIAVITGGNRGIGLRIV 84
            |.|..:|:.||.:|...:   |:|.     .|.::..|.|..:         |||.|.|||....
 Frog    10 FLKGMREYTKSGYETAAK---QFLS-----EDLEFDVRGRSYM---------ITGANSGIGKAAA 57

  Fly    85 EKLLACDMTVVMGVRDPKIAETAVASIVDLNATKGK--LICEQLDVGDLKSVKAFAQLIKERYSK 147
            ..:.....|:.:..|:.:.||.|..   :|.|..|.  :....||:.|.|.:..||:..|..: |
 Frog    58 LVIAKKGGTIHLVCRNKERAEEAQR---ELKANSGNEDISVHLLDMSDPKQIWEFAEKFKTEH-K 118

  Fly   148 VDLLLNNAGIMFAPFKLTADGYESHFAINFLGHFLLTHLLLPQLRAAGKEGRNSRIVNVSSCVNL 212
            :::|:||||.|....:||.||.|.:||.|.||.::||..|||.|.   || .:.|::.|||...|
 Frog   119 LNVLINNAGCMVNKRELTEDGLEKNFATNTLGTYILTTALLPSLE---KE-EDPRVITVSSGGML 179

  Fly   213 IGRINYKDINGTKHYYPGT-AYSQSKLAQILFTRHLQTLLDAEKSHVQVNVVHPGIVDTDLFEHS 276
            :.::|..|:......:.|| ||:|:|..|::.|....    ....:|..:|:|||..||.    :
 Frog   180 VQKLNVSDLQFETGTFDGTMAYAQNKRQQVILTEQWA----KANPNVHFSVMHPGWADTP----A 236

  Fly   277 ATTSVPIF---KKLFFKTPERGSRTVVFAAIDPS 307
            ..:|:|.|   .|...:|.|:|:.|||:..:.||
 Frog   237 VRSSMPDFYEKMKNRLRTEEQGADTVVWLTLSPS 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11200	NP_611471.1	Rossmann-fold NAD(P)(+)-binding proteins	67..338	CDD:473865	81/247 (33%)
dhrs12	NP_001072547.1	DHRS-12_like_SDR_c-like	40..293	CDD:187668	82/256 (32%)