DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11200 and 1700003E16Rik

DIOPT Version :9

Sequence 1:	NP_001286630.1	Gene:	CG11200 / 37301	FlyBaseID:	FBgn0034500	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_082224.1	Gene:	1700003E16Rik / 71837	MGIID:	1919087	Length:	598	Species:	Mus musculus

Alignment Length:	308	Identity:	66/308 - (21%)
Similarity:	101/308 - (32%)	Gaps:	90/308 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 DPKIAETAVASIV---------DLNATKGKLICEQLDVGDLKSVKAFAQLIKERYSKVDLLLNNA 155
            :||:.....|::.         .|....|:.....|.|...:|:::.|:  .||.......|...
Mouse   184 EPKVTPRPTATLEAFEEAEPGDALEVPHGQEGSHMLAVPSKESLRSTAE--GERVYSPQSSLKQP 246

  Fly   156 GIMFAPFKLTADGYESHFAINFLGHFLL--THLLLPQLRAAGKEGRNSRIVNVSSCVNLIGRINY 218
            .::    :|.|...||.|.    .|..|  .:|.:||..|||     .|:...|.     |:::.
Mouse   247 QVV----RLQASEKESSFG----SHLSLEDLYLCMPQPDAAG-----DRLSLQSK-----GQLHS 293

  Fly   219 KDINGTKHYYPGTAYSQSKL--AQILFTR--HLQTLLDAEKSHVQVNVVHP--GIVDTDLFEH-- 275
            ..|....|....|....|..  .::|..|  |..|.|..:.|.:..:.|.|  .::..||..|
Mouse   294 SPIGSESHLGALTPAEPSAFQEPEVLGERPKHKTTTLRMDSSRLPRHWVRPVAEVLIPDLEVHPL 358

  Fly   276 ------------SATTSVPIFKKLFFKTPERG---------SRTVVFAAI--DPSIE-------- 309
                        ...||....:.|..:.|.:.         .|...|.|:  |||:.
Mouse   359 EIYRGRPRRSQAGTATSACESQALSSRAPSKPHVSSPRFPLQRCATFRALGPDPSLNLAQTSPSF 423

  Fly   310 GQGGTYLSNG----GKGPFHPD------------AKKPA----KCEQL 337
            |....:||.|    .:.|..||            ||.|:    :.|||
Mouse   424 GSNVPFLSPGFRFLPRNPIPPDVASTPTPKLWPLAKWPSGWEREAEQL 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11200	NP_001286630.1	PRK06196	56..344	CDD:235736	66/308 (21%)
CG11200	NP_001286630.1	NADB_Rossmann	67..338	CDD:304358	66/308 (21%)
1700003E16Rik	NP_082224.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
		DUF4639	6..571	CDD:292118	66/308 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	151..190		2/5 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	222..241		4/20 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	366..396		4/29 (14%)
		LamG	<436..>463	CDD:304605	6/26 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	551..571
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900