DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11200 and Dhrs13

DIOPT Version :9

Sequence 1:	NP_001286630.1	Gene:	CG11200 / 37301	FlyBaseID:	FBgn0034500	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_899109.2	Gene:	Dhrs13 / 70451	MGIID:	1917701	Length:	376	Species:	Mus musculus

Alignment Length:	307	Identity:	97/307 - (31%)
Similarity:	147/307 - (47%)	Gaps:	23/307 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 LGIVGLVHDAQYKARDRVALYKQPDRIAVITGGNRGIGLRIVEKLLACDMTVVMGVRDPKIAETA 107
            ||...||:....||.....:.....|..|:||.|.|||.....:|......||:..|.   .|..
Mouse    12 LGAYVLVYYNLVKAPSCGGIGSLRGRTVVVTGANSGIGKMTALELARRGARVVLACRS---RERG 73

  Fly   108 VASIVDLNATKG--KLICEQLDVGDLKSVKAFAQLIKERYSKVDLLLNNAGIMFAPFKLTADGYE 170
            .|:..||....|  ::|...||:..|.||:|||........::|:|::||||  :....|.:.:.
Mouse    74 EAAAFDLRQESGNNEVIFMALDLASLASVQAFATAFLSSEPRLDVLIHNAGI--SSCGRTRETFN 136

  Fly   171 SHFAINFLGHFLLTHLLLPQLRAAGKEGRNSRIVNVSSCVNLIGRINYKDIN----GTKHYYPGT 231
            ....:|.:|.|||||||||:||:...    ||:|.|||..:..||:::..::    |.:...  .
Mouse   137 LLLRVNHVGPFLLTHLLLPRLRSCAP----SRVVIVSSAAHRRGRLDFTRLDCPVVGWQQEL--R 195

  Fly   232 AYSQSKLAQILFTRHLQTLLDAEKSHVQVNVVHPGIVDTDLF-EHSATTSVPIFKK---LFFKTP 292
            ||:.||||.:||.|.|.|.|  |.:.|.....|||.|:::|| .|......||.:.   |..:.|
Mouse   196 AYADSKLANVLFARELATQL--EGTGVTCYAAHPGPVNSELFLRHLPGWLRPILRPLAWLVLRAP 258

  Fly   293 ERGSRTVVFAAIDPSIEGQGGTYLSNGGKGPFHPDAKKPAKCEQLFQ 339
            :.|::|.::.|:...||...|.|.:|.......|.|:.....::|::
Mouse   259 QGGAQTPLYCALQEGIEPLSGRYFANCHVEEVSPAARDDQAAQRLWK 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11200	NP_001286630.1	PRK06196	56..344	CDD:235736	92/294 (31%)
CG11200	NP_001286630.1	NADB_Rossmann	67..338	CDD:304358	90/280 (32%)
Dhrs13	NP_899109.2	PRK06197	31..312	CDD:235737	91/288 (32%)
		retinol-DH_like_SDR_c_like	36..304	CDD:212492	90/280 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	311..376
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810