Protein Alignment CG11200 and RDH14

DIOPT Version :9

• Sequence 1: NP_001286630.1
• Gene: CG11200 / 37301
• FlyBaseID: FBgn0034500
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_065956.1
• Gene: RDH14 / 57665
• HGNCID: 19979
• Length: 336
• Species: Homo sapiens
• Alignment Length: 366
• Identity: 126/366 - (34%)
• Similarity: 174/366 - (47%)
• Gaps: 76/366 - (20%)

  Fly     2 LGTLLWIF---FVGLLLCAFLFSKTTKEFPKSWFEWKTEFRYQYL---GIVGLVHDAQYKARDRV 60
            ||..||:.   |||               |          |.|.|   |..||:|
Human    13 LGGALWLAARRFVG---------------P----------RVQRLRRGGDPGLMH---------- 42

  Fly    61 ALYKQPDRIAVITGGNRGIGLRIVEKLLACDMTVVMGVRDPKIAETAVASI-VDLNATK------ 118
                  .:..:|||.|.|:|.....:||.....|:||.||...||.|...: .:|....
Human    43 ------GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEP 101

  Fly   119 -----GKLICEQLDVGDLKSVKAFAQLIKERYSKVDLLLNNAGIMFAPFKLTADGYESHFAINFL 178
                 |:||..:||:..|:||:||.|.:.:...::|:|:|||||...|:..|.||:|..|.:|.|
Human   102 GVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHL 166

  Fly   179 GHFLLTHLLLPQLRAAGKEGRNSRIVNVSSCVNLIGRINYKDINGTKHYYPGTAYSQSKLAQILF 243
            ||||||:|||..|:::..    ||||.|||.:...|.||:.|:|..:.|.....||:||||.|||
Human   167 GHFLLTNLLLGLLKSSAP----SRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILF 227

  Fly   244 TRHLQTLLDAEKSHVQVNVVHPGIVDTDLFEHSATTSVPIFKK--------LFFKTPERGSRTVV 300
            ||.|...|  |.::|.|||:|||||.|:|..|   ..:|:..|        .|||||..|::|.:
Human   228 TRELARRL--EGTNVTVNVLHPGIVRTNLGRH---IHIPLLVKPLFNLVSWAFFKTPVEGAQTSI 287

  Fly   301 FAAIDPSIEGQGGTYLSNGGKGPFHPDAKKPAKCEQLFQFS 341
            :.|..|.:||..|.|..:..:....|.|...:...:|:..|
Human   288 YLASSPEVEGVSGRYFGDCKEEELLPKAMDESVARKLWDIS 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11200	NP_001286630.1	PRK06196	56..344	CDD:235736	111/306 (36%)
		NADB_Rossmann	67..338	CDD:304358	109/290 (38%)
RDH14	NP_065956.1	retinol-DH_like_SDR_c	43..328	CDD:212495	110/293 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810