Protein Alignment CG11200 and rdh12

DIOPT Version :10

• Sequence 1: NP_611471.1
• Gene: CG11200 / 37301
• FlyBaseID: FBgn0034500
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_001002325.2
• Gene: rdh12 / 436597
• ZFINID: ZDB-GENE-040718-9
• Length: 320
• Species: Danio rerio
• Alignment Length: 320
• Identity: 111/320 - (34%)
• Similarity: 165/320 - (51%)
• Gaps: 27/320 - (8%)

  Fly    43 LGIVGLV----------HDAQYKARDRVALYKQPDRIAVITGGNRGIGLRIVEKLLACDMTVVMG 97
            ||:|.|:          :.|....|..|.|   ..::|::||.|.|||......|.:....|::.
Zfish    12 LGLVALILRLLSPQIRKYAAGGSCRSTVRL---DGKVALVTGANSGIGKETALDLASRGARVILA 73

  Fly    98 VRDPKIAETAVASIVDLNATK---GKLICEQLDVGDLKSVKAFAQLIKERYSKVDLLLNNAGIMF 159
            .||.:.||.|.|.|    .|:   .|:...:||:.|..|::||||........:.:|:||||:|.
Zfish    74 CRDLEKAEEAAAEI----RTRVGGAKVEVRELDLADCCSIRAFAQRFLREVDHLHILINNAGVMM 134

  Fly   160 APFKLTADGYESHFAINFLGHFLLTHLLLPQLRAAGKEGRNSRIVNVSSCVNLIGRINYKDINGT 224
            .|:..||||:|....:|.|||:|||:||:..|    |....||||.|||..:..|.|.:.|::..
Zfish   135 CPYMKTADGFEMQIGVNHLGHYLLTYLLIGLL----KRSAPSRIVVVSSLAHNFGWIRFHDLHSQ 195

  Fly   225 KHYYPGTAYSQSKLAQILFTRHLQTLLDAEKSHVQVNVVHPGIVDTDLFEHSATTSVPI-FKKLF 288
            ..|..|.||.|||||.:||||.|...|  :.|:|.||.||||.|.::|..||...|:.. |..:|
Zfish   196 GSYNSGLAYCQSKLANVLFTRELARRL--QGSNVTVNSVHPGTVRSELVRHSTLMSLLFAFFSMF 258

  Fly   289 FKTPERGSRTVVFAAIDPSIEGQGGTYLSNGGKGPFHPDAKKPAKCEQLFQFSCDLLKIQ 348
            .|:|:.|::|.::.|:...::...|.:.|:.......|..:......:|:..||:||.|:
Zfish   259 LKSPKEGAQTSIYCAVAEELQSISGKHFSDCAPAFVAPQGRSEETARKLWDVSCELLGIE 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11200	NP_611471.1	Rossmann-fold NAD(P)(+)-binding proteins	67..338	CDD:473865	97/274 (35%)
rdh12	NP_001002325.2	Rossmann-fold NAD(P)(+)-binding proteins	43..311	CDD:473865	98/277 (35%)