DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11200 and Wwox

DIOPT Version :9

Sequence 1:	NP_001286630.1	Gene:	CG11200 / 37301	FlyBaseID:	FBgn0034500	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_006255728.1	Gene:	Wwox / 292041	RGDID:	1309927	Length:	414	Species:	Rattus norvegicus

Alignment Length:	271	Identity:	83/271 - (30%)
Similarity:	131/271 - (48%)	Gaps:	37/271 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 RIAVITGGNRGIGLRIVEKLLACDMTVVMGVRDPKIAETAVASIVDLNATKGKLICEQLDVGDLK 132
            ::.::||.|.|||....:........|::..|:...|..||:.|:: ...|.|:....||:..|:
  Rat   125 KVVLVTGANSGIGFETAKSFALHGAHVILACRNMSRASEAVSRILE-EWHKAKVEAMTLDLAVLR 188

  Fly   133 SVKAFAQLIKERYSKVDLLLNNAGIMFAPFKLTADGYESHFAINFLGHFLLTHLLLPQL-RAAGK 196
            ||:.||:..|.:...:.:|:.|||....|:.||.||.|:.|.:|.||||.|..||...| |:|
  Rat   189 SVQHFAEAFKAKNVPLHILVCNAGTFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSA-- 251

  Fly   197 EGRNSRIVNVSSCVNLIGRINYKDIN-------------GTKHYYPGTAYSQSKLAQILFTRHLQ 248
               .:|::.|||..:     .:.|||             .:..|:...||::|||..|||:..|.
  Rat   252 ---PARVIVVSSESH-----RFTDINDSSGKLDLSRLSLSSSDYWAMLAYNRSKLCNILFSNELH 308

  Fly   249 TLLDAEKSHVQVNVVHPGIVDTDLFEHSATTSVPIFKKL------FFKTPERGSRTVVFAAIDPS 307
            .||...  .|..|.:|||.:.......::.    ::|.|      |.|:.::|:.|.|:.|:.|.
  Rat   309 RLLSPR--GVTSNALHPGNMMFSAIHRNSW----VYKLLFTLARPFTKSMQQGAATTVYCAVAPE 367

  Fly   308 IEGQGGTYLSN 318
            :||.||.|.:|
  Rat   368 LEGLGGMYFNN 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11200	NP_001286630.1	PRK06196	56..344	CDD:235736	83/271 (31%)
CG11200	NP_001286630.1	NADB_Rossmann	67..338	CDD:304358	83/271 (31%)
Wwox	XP_006255728.1	WW	18..47	CDD:395320
		WW	60..90	CDD:238122
		human_WWOX_like_SDR_c-like	124..407	CDD:187669	83/271 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000