Protein Alignment CG11200 and RDH12

DIOPT Version :9

• Sequence 1: NP_001286630.1
• Gene: CG11200 / 37301
• FlyBaseID: FBgn0034500
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_689656.2
• Gene: RDH12 / 145226
• HGNCID: 19977
• Length: 316
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 104/285 - (36%)
• Similarity: 161/285 - (56%)
• Gaps: 10/285 - (3%)

  Fly    66 PDRIAVITGGNRGIGLRIVEKLLACDMTVVMGVRDPKIAETAVASIVDLNATKGKLICEQLDVGD 130
            |.::.||||.|.|||.....:|.:....|.:..||....|:| ||.:.::....:::..:||:.|
Human    38 PGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESA-ASEIRVDTKNSQVLVRKLDLSD 101

  Fly   131 LKSVKAFAQLIKERYSKVDLLLNNAGIMFAPFKLTADGYESHFAINFLGHFLLTHLLLPQLRAAG 195
            .||::|||:.......::.:|:||||:|..|:..||||:|:|..:|.|||||||:|||.:|:.:.
Human   102 TKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGVNHLGHFLLTYLLLERLKVSA 166

  Fly   196 KEGRNSRIVNVSSCVNLIGRINYKDINGTKHYYPGTAYSQSKLAQILFTRHLQTLLDAEKSHVQV 260
            .    :|:|||||..:.||:|.:.|:...|.|..|.||..||||.:||||.|...|  :.:.|..
Human   167 P----ARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLANVLFTRELAKRL--QGTGVTT 225

  Fly   261 NVVHPGIVDTDLFEHSATTSV--PIFKKLFFKTPERGSRTVVFAAIDPSIEGQGGTYLSNGGKGP 323
            ..||||:|.::|..||:...:  .:|.. |.||...|::|.:..|:...:|...|.|.|:..:..
Human   226 YAVHPGVVRSELVRHSSLLCLLWRLFSP-FVKTAREGAQTSLHCALAEGLEPLSGKYFSDCKRTW 289

  Fly   324 FHPDAKKPAKCEQLFQFSCDLLKIQ 348
            ..|.|:.....|:|:..||:||.|:
Human   290 VSPRARNNKTAERLWNVSCELLGIR 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11200	NP_001286630.1	PRK06196	56..344	CDD:235736	101/279 (36%)
		NADB_Rossmann	67..338	CDD:304358	97/272 (36%)
RDH12	NP_689656.2	retinol-DH_like_SDR_c	39..307	CDD:212495	98/275 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810