Protein Alignment CG11200 and RDH13

DIOPT Version :10

• Sequence 1: NP_611471.1
• Gene: CG11200 / 37301
• FlyBaseID: FBgn0034500
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_001139443.1
• Gene: RDH13 / 112724
• HGNCID: 19978
• Length: 331
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 102/297 - (34%)
• Similarity: 156/297 - (52%)
• Gaps: 27/297 - (9%)

  Fly    66 PDRIAVITGGNRGIGLRIVEKLLACDMTVVMGVRDPKIAETAVASIVDLNATKGKLI-----CEQ 125
            |.:..::||.|.|||.:...:|......:::..||.:..|.|...|      :|:.:     ...
Human    37 PGKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDI------RGETLNHHVNARH 95

  Fly   126 LDVGDLKSVKAFAQLIKERYSKVDLLLNNAGIMFAPFKLTADGYESHFAINFLGHFLLTHLLLPQ 190
            ||:..|||::.||..|.|...:||:|:||||:|..|...|.||:|..|.:|.|||||||:|||.:
Human    96 LDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLLLDK 160

  Fly   191 LRAAGKEGRNSRIVNVSSCVNLIGRINYKDIN-GTKHYYPGTAYSQSKLAQILFTRHLQTLLDAE 254
            |:|:..    |||:|:||..::.|.|::.|:| .|:.|....||.|||||.:|||:.|...|  :
Human   161 LKASAP----SRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSRRL--Q 219

  Fly   255 KSHVQVNVVHPGIVDTDLFEH--------SATTSVPIFKKLFFKTPERGSRTVVFAAIDPSIEGQ 311
            .|.|.||.:|||:..|:|..|        |:||..||| .|..|:||..::...:.|:...:...
Human   220 GSGVTVNALHPGVARTELGRHTGIHGSTFSSTTLGPIF-WLLVKSPELAAQPSTYLAVAEELADV 283

  Fly   312 GGTYLSNGGKGPFHPDAKKPAKCEQLFQFSCDLLKIQ 348
            .|.|.....:....|:|:......:|:..|..|:.::
Human   284 SGKYFDGLKQKAPAPEAEDEEVARRLWAESARLVGLE 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11200	NP_611471.1	Rossmann-fold NAD(P)(+)-binding proteins	67..338	CDD:473865	98/284 (35%)
RDH13	NP_001139443.1	retinol-DH_like_SDR_c	38..313	CDD:212495	99/287 (34%)