Protein Alignment CG16868 and CG4587

DIOPT Version :9

• Sequence 1: NP_611469.1
• Gene: CG16868 / 37298
• FlyBaseID: FBgn0034498
• Length: 1449
• Species: Drosophila melanogaster
• Sequence 2: NP_001188817.2
• Gene: CG4587 / 34921
• FlyBaseID: FBgn0028863
• Length: 1271
• Species: Drosophila melanogaster
• Alignment Length: 1175
• Identity: 209/1175 - (17%)
• Similarity: 375/1175 - (31%)
• Gaps: 424/1175 - (36%)

  Fly    10 VLLILAVLACPTSSQHVPLAMANSTSNQVPTDPGFMPLQQSPGSVFFVHHNQQNAMQLRHSMEGK 74
            |.::|.||   ....|:.:|.|:...:                    :.||:
  Fly    10 VAIVLGVL---IFKMHIFVAFADQDED--------------------IPHNE------------- 38

  Fly    75 LRNIRNTELRVA----KIQEIFDSMHFSSAKGASNTRQASSNDSNVVNPQLQRDLQLFSE----- 130
               :||..|:..    :....|..|:...::...|..:....|..::..:|..:::.|.:
  Fly    39 ---VRNWALKFGVDLWEFGRQFTKMNEIKSRFKDNDIEVKRKDGIILLRELAAEVKNFMDFKRNA 100

  Fly   131 --RLSKKIQKATYVVLE--------LRELLRYNLTKVWQYSYDDEDDESESEMDLEM--ELEDLH 183
              ||....::|....||        :.....|:..::.:|:.|.:..:....||:..  ..|.|.
  Fly   101 VMRLMDSAEQAALSELEGQGQAESPMGGQQHYDARRINEYNADGKLADGARHMDIRFMRRFERLP 165

  Fly   184 ARNTASPTDEHVQLYLNTQIESCQPDYETDLEYGSSSTQSIHYNRQQIQILNYLKSDDARATFLN 248
            ...:.|      .:.:...::..:||.::.|::..........|.:|...|::
  Fly   166 VNLSLS------SILVPHGVDLDEPDVKSALQWSGHLDPLFQNNLEQDPALSW------------ 212

  Fly   249 ENNARSLAVNGYISNQLVLLKRRLSRS-DAENSNSKPISGNHFKHIYFLSNSDGASASLHFRQLY 312
                      .|..:....|:|....: ..|.|....:..:...|.:|:.
  Fly   213 ----------QYFGSSTGFLRRFPGTAWPPEGSKGSKLIHDFRTHNWFVQ--------------- 252

  Fly   313 VSAIKQKFVLFLIDVGSALSAELFDLSKSFVHEMLQLLEDTDKVSLVTVASEANFMSLEAFPAEA 377
             :|...|.::.|:|..|:::.:.|||..:....:|..|.:.|.|:|:|. ||.....:..|...
  Fly   253 -AASSPKDIMILLDASSSMTEKSFDLGMATAFNILDTLGEDDFVNLITF-SEVVKTPVPCFKDR- 314

  Fly   378 GHGIYSATRAHKEEIISFINSLSRAQAFTNHSLGFEYSFELLHRLQQSG---------------- 426
               :..||..:.:||.|.:.:: :.|...|.:.|.||:|.|||:..|||
  Fly   315 ---MVRATPDNIQEIKSAVKAI-KLQDTANFTAGLEYAFSLLHKYNQSGAGSQCNQAIMLITEST 375

  Fly   427 ---------MINTAEQPVE-FVYI-----------------TRGLLTNLSDAMAVLRVVADGQRR 464
                     ..|....||. |.|:                 .:|....::|.....|.|.|
  Fly   376 SESHKDVIKQYNWPHMPVRIFTYLIGSDSGSRSNLHDMACSNKGFFVQINDYDEARRKVID---- 436

  Fly   465 LRAPVIINTCAVVLDEKRIMYEKQFLNDVASQNYTKYEIDVASWWPSGQEASELVGRFYVLSKMH 529
                     .|:|:....|||:..               ....|.|           .:|..|
  Fly   437 ---------YALVMARPMIMYQAD---------------HPVHWSP-----------VFVAGK-- 464

  Fly   530 AETSLPQTSSRIFGPLFQERYLSDTLEVHPPVVDADSGDVLVSITHAVPPYGVVGVNLYLSDLLE 594
             ...|.:.|.      :|.|.::   .|..||.|..:..|.|:..     .||||.::.:.::.:
  Fly   465 -SGGLGRDSE------YQRRLVT---TVSTPVFDRRNHSVRVANL-----LGVVGTDVPIEEIRK 514

  Fly   595 DLLNYPSTTSSAKQG-LGYAFLLDRSTGNTLAHPAFPRPL-------IQRETSY-PVNIAYLE-N 649
            .:..:       |.| .||:|::| :.|..|.||.. |||       .|.:..| .|:|..|| .
  Fly   515 VIPQH-------KLGPNGYSFIVD-NNGRVLYHPDL-RPLGDANQYIDQLKPKYASVDITELELP 570

  Fly   650 ATDFSSH-----IRDRLLRE----------------------ESGNVTTDV-------------- 673
            .|:|.::     |...||.|                      :|..|:|..
  Fly   571 ETEFGNNNEPIEINKNLLNEMRGDMIKPKEGETEFTVMNHYDDSKRVSTRTHRYFYGPIEDTPFT 635

  Fly   674 -------------YVGRQRLQRT------YY----WQSVLGFYVLCLVSSGGDTLRNVSSTQRYN 715
                         :|.:|.::.:      |:    |: |...:|.|..:|..|..:...|:..|:
  Fly   636 LAIVLPEKYGSHEFVSQQEIRHSRNNVTEYFKGDNWR-VHPDWVYCEYNSVSDLEKERESSGEYS 699

  Fly   716 LKDTVSNYEPGYYGESMDLLYHRLDL-------------------------NQGGSAPPKTCRYF 755
            .:|    .||. :|...:.:.|.|..                         :.||:||.
  Fly   700 SRD----QEPS-FGSPEEQVLHFLSRAGRPGWKWMSVRPKSPQPHHNMHSGSNGGNAPG------ 753

  Fly   756 RQVATMDAPTLFLSAAAFESPFGFLHNNRPRTQLRHVES-------IMAYLRD---SSGLLANMG 810
                              .|.||..|.:...:  |..|.       :.:.:||   :.||..|..
  Fly   754 ------------------SSHFGSQHQSSQGS--RKAEPYFCDRALLQSLVRDAMVTDGLDRNTT 798

  Fly   811 LRPSIRHEVGVLYQAMQQLRRRHQDARGSLRSHVIRRYIASVSGVLQLYPGCLLSSSYDPTRRP- 874
            ...|.:.:...:...|..|:|     :|..:..|...::|:.||:|:.         .|..:||
  Fly   799 GSSSGKEDKHPIATLMAILKR-----QGYQKFVVATSFVATRSGLLRW---------IDHVKRPE 849

  Fly   875 ------------------WFRQAIAQ----PGKIVSTAPYLDAGGAGY-------IITIAHTIFE 910
                              |:::||.|    |...|.:.|:    |:||       ::|.:|.||
  Fly   850 DTPEPHFSEDNVRAMDTSWYKRAIDQHSVEPDSFVYSVPF----GSGYAIKSNATLVTASHAIF- 909

  Fly   911 GKAHALHSAQQDRPVAVVALDVPYAFYYRLILEGTP----------ICQLPHIKCLLFEHEGYLL 965
             ..|..|.|    ...||.|...:....:..:..|.          .|...::.|.:.::.|:::
  Fly   910 -VEHRGHKA----AAGVVGLQFQHDSLAKHFINITSACTGMTGCKRTCASDNLDCYVLDNSGFVI 969

  Fly   966 AHPSM 970
            ....|
  Fly   970 ISEEM 974

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16868	NP_611469.1	vWFA	308..>426	CDD:294047	32/117 (27%)
		Cache_1	559..627	CDD:280839	17/68 (25%)
CG4587	NP_001188817.2	VWA_N	108..230	CDD:285584	20/149 (13%)
		vWA_VGCC_like	245..428	CDD:238740	43/204 (21%)
		Cache_1	456..544	CDD:280839	28/124 (23%)
		VGCC_alpha2	590..>647	CDD:285647	4/56 (7%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10166
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010