Protein Alignment CG16868 and unc-36

DIOPT Version :9

• Sequence 1: NP_611469.1
• Gene: CG16868 / 37298
• FlyBaseID: FBgn0034498
• Length: 1449
• Species: Drosophila melanogaster
• Sequence 2: NP_001040851.1
• Gene: unc-36 / 176155
• WormBaseID: WBGene00006772
• Length: 1249
• Species: Caenorhabditis elegans
• Alignment Length: 1122
• Identity: 201/1122 - (17%)
• Similarity: 376/1122 - (33%)
• Gaps: 354/1122 - (31%)

  Fly   111 SNDSNVVNPQLQRDLQLFSERLSKKIQKATYVVLELRELLRYNLTK-VWQYSYDDEDDESESEMD 174
            |..|:.....::...::.||.:     |.|:..:....:|:.|..| |.:..:|...:..:|:..
 Worm    15 STTSSFNKESIKECAKVLSEHM-----KETFSKISHETILKQNYEKLVEEEQFDPRAELKKSKHR 74

  Fly   175 LE--------------MELEDLHARNTASPTDEHVQLYLNTQIESCQPDYETDLEYGSSSTQSIH 225
            :|              :.||....||.::..|...:.::.........|       |::..:|.|
 Worm    75 IEDYLKVRSQFAYKAKISLEARSVRNDSTVNDPQSKSFIRFMSAKQGND-------GTTIYESNH 132

  Fly   226 YNRQQIQILNYLKSDDARATFLNEN-NARSLAVNG-----------YISNQLVLLKRRLSRSDA- 277
            ..::       ||.::.::..|.:| |..:|..:.           |..|:.:|.|...|..||
 Worm   133 LGKR-------LKVNETKSFNLTQNANFYTLPTSSVSSAVHIPTPLYDRNEDLLRKIDWSDIDAV 190

  Fly   278 ---ENSNSKPIS-------GNHFKHI----YFLSNSDGASASLHFR--QLYV-SAIKQKFVLFLI 325
               ....:|.::       ..:.::.    :|..|.|........|  :.|: ||...|.||.::
 Worm   191 YRTNREETKDLAFQLFCSEAGYMRYYPAASWFWDNQDEHLDLFDCRNTEWYINSATNSKNVLIML 255

  Fly   326 DVGSALSAELFDLSKSFVHEMLQLLEDTDKVSLVTVASEANFMSLEAFPAEAGHGIYSATRAHKE 390
            |:..::..:.::::|.....:|:.|...|..:::|.:.  |...|:.  ....:|:..||..:|:
 Worm   256 DMSGSMLGQRYEVAKQTTEAILETLSHNDYFNIMTFSK--NTFLLDG--CNGTNGLLQATMRNKK 316

  Fly   391 EIISFINSLSRAQAFTNHSLG-FEY------SFELLHRLQQSGMINTAEQ--------------- 433
            .:        |.:..|..|.| .||      :|.:|..|:.|..:.|.|:
 Worm   317 AL--------RRKMDTYQSEGKAEYEKALPLAFSVLLDLKGSYALYTKEEMSMMSANATNEYQFH 373

  Fly   434 ---PVEFVYITRGLLTNLSDAMA---------VLRVVADG--------------QRRLRA-PVII 471
               |...:..|:..:.::::...         |:.::.||              .:::|. ..::
 Worm   374 LELPEHVLAATKQYIDSINNGGGDNNRGACENVIMLITDGAPNAYKKIFDMYNADKKVRVFTFLV 438

  Fly   472 NTCAVVLDEKRIMY-----------------EK-----QFLNDVASQNYTKYEIDVASWW----- 509
            ...|:..:|.|.|.                 ||     :.::.|..::|.  |....|||
 Worm   439 GDEAIDFNEVREMACNNRGYMVHVANMADVDEKIHHYIRRMSRVVGRHYK--ESGQLSWWTGVYR 501

  Fly   510 -----PSGQEASELV----GRFYVLSKMHAETSL----PQTSSRIFGPLFQERYLSDTLEVHPPV 561
                 |..:..:|.|    ..|.|::||.:...:    .:..||:|
 Worm   502 ERLYLPRPEIFAEPVPITNQSFAVMNKMASRRKIRLQKSEARSRMF------------------- 547

  Fly   562 VDADSGDVLVSITHAVPPYGVVGVNLYLSDLLEDLLNYPSTTSSAKQGLGYAFLLDRSTGNTLAH 626
            |...|..|:|:.|.    .||..||:.|:::.:.  ::|:...|.    .|.|:||:: |..:.|
 Worm   548 VTTVSYPVIVNETF----MGVAAVNIPLTEVAQK--SHPANIGSK----SYFFMLDQN-GFVMTH 601

  Fly   627 PAFPRP----------------LIQRETSYPVNIA------------------YLENATDFSSHI 657
            |.. ||                |::.|.....|:.                  |.|...|....:
 Worm   602 PQL-RPIDPFTKYHKQNYNNMDLLELEVGQNQNVRSSQKSQAVSDLVCESGANYAECVDDLRKAV 665

  Fly   658 RDRLLREESGNV-TTDVYVGRQRLQRTY-----YWQSVLGF--YVLCLVSSGGDTLRNVSSTQRY 714
            |..::..::.:| ..||....:.|.|.|     |:...:..  :||.|..:.||..|.|...::|
 Worm   666 RKMIIDCDNSDVQQLDVLYATELLDRVYPQTNTYYAECINHANFVLGLAVAKGDDYRVVKKQKKY 730

  Fly   715 --------------------------NLKDTVSNYEPGY--YGESMDLLYHRLDLNQGGSAPPKT 751
                                      |..||..:.|..:  |.:.|         :..|.| |..
 Worm   731 DFGRVKMDWMGDKRWRLHPHWRYCFLNDTDTHMSKEEAFEIYAQQM---------SDSGKA-PLL 785

  Fly   752 CRYFRQVA-----TMDAPTLFLSAAAFESPFGFLHNN--------RPRTQLRHVESIMA---YLR 800
            |.|.|.:.     .|:|.:..:.  ::::.|.|:.||        .|...:|:....:.   |:.
 Worm   786 CEYRRNLVEKLLLDMEATSNLID--SWDTQFNFMKNNLIHLAFFATPSGMIRYYNLTLQDYDYID 848

  Fly   801 DSSGLLANMGLRPSIRHEVGVLYQAMQQLRRRHQDARGSLRSHVIRRYIASVSGVLQLYPGCLLS 865
            ....:..::|...||.|........:..|.|:..|.|      ..||.:.....::
 Worm   849 PYWSIFEHIGHLLSIEHAQESYNHFITDLNRKSTDDR------YYRRAVRMKDTIM--------- 898

  Fly   866 SSYDPTR--RPWFRQAIAQPGKIVS----------TAPYLD---AGGAGYIITIAHTIFEGKAHA 915
              :|.:.  :.|::......|..::          .|.|||   .|.:|:.....|.:.....|.
 Worm   899 --FDVSNNSKIWYKSETQLTGYGLNENLTMLGQAFKAIYLDKAVLGVSGFEFAYDHVVDTMAEHG 961

  Fly   916 LHSAQQDRPVAVVALDVPYAFYYR---------LILEGTPICQ--------LPHIKCLLFEHEGY 963
            . .|..||...|:..:..|.|:..         |:.:|..|.|        ......||.|::.|
 Worm   962 C-PASDDRKWCVLLDEHAYVFFSNQNDISYEDYLVGKGKHISQYFGGLNRIAQRAMALLVENKFY 1025

  Fly   964 LLAHPSMLQPATLTKNQ 980
                    ...|.|.||
 Worm  1026 --------TKLTYTDNQ 1034

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16868	NP_611469.1	vWFA	308..>426	CDD:294047	28/127 (22%)
		Cache_1	559..627	CDD:280839	17/67 (25%)
unc-36	NP_001040851.1	VWA_N	95..221	CDD:285584	21/139 (15%)
		vWA_VGCC_like	236..466	CDD:238740	41/241 (17%)
		Cache_1	548..606	CDD:280839	19/69 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910