Protein Alignment CG16868 and tag-180

DIOPT Version :9

• Sequence 1: NP_611469.1
• Gene: CG16868 / 37298
• FlyBaseID: FBgn0034498
• Length: 1449
• Species: Drosophila melanogaster
• Sequence 2: NP_001022363.1
• Gene: tag-180 / 174730
• WormBaseID: WBGene00007041
• Length: 1067
• Species: Caenorhabditis elegans
• Alignment Length: 1383
• Identity: 236/1383 - (17%)
• Similarity: 432/1383 - (31%)
• Gaps: 506/1383 - (36%)

  Fly    36 NQVPTDPGFMPLQQSPGSVFFVHHNQQNAMQLRHSMEGKLRNIRNTELRVAKIQEIFDSMHFSSA 100
            :|:|.|    .::::|.|:     .|.:|..||..         .|:.|.:.:||.|:
 Worm    14 SQLPVD----TIEEAPASI-----AQFSANILRDF---------ETQSRFSLVQEEFE------- 53

  Fly   101 KGASNTRQASSNDSNVVNPQLQRDLQLFSERLSKKIQKATYVVLELRELL--RYNLTKVWQYS-- 161
                               :|:.|::...|..::|::.||.   .|..|:  |.:..|....|
 Worm    54 -------------------KLKPDIKSKKEDAAEKLRVATE---HLDRLVTNRVDALKKLASSAE 96

  Fly   162 -----YDDEDDESESEMDLEMELEDLHARNTASPTDEHVQLYLNTQIESCQPDYETDLEYGSSST 221
                 :|:.||::.:                ....|:..:.|:....||       |:.:.|:
 Worm    97 ASAAVFDEYDDQAYA----------------VPQADKRCEAYMKKMNES-------DMHFVSN-- 136

  Fly   222 QSIHYNRQQIQILNYLKSDDARATFLNENNARS---LAVNGYISNQLVLL------KRRLSRSDA 277
                                     :.|:|::|   :.|..|..:..|:.      .:.|.::.:
 Worm   137 -------------------------MVEHNSKSGIHITVESYQCDPRVMRDFDWTGTKHLEKTMS 176

  Fly   278 ENSNSKPISGNHFKHIYFLSNSDGASASL-------------------HFRQLYVSAIK-QKFVL 322
            :|....|..|:.:...|     .|.:...                   .||..:|:|.. .|.::
 Worm   177 DNKEKAPEMGHQYIGTY-----SGLTRMYPRRHWKVEPTPITIDLFDPRFRPWFVNAESVPKDIV 236

  Fly   323 FLIDVGSALSAELFDLSKSFVHEMLQLLEDTDKVSLVTVASEANFMSLEAFPAEAGHGIYSATRA 387
            ||:|...::......|.|..:..:|..|.                      |.:...|:|  ...
 Worm   237 FLLDYSGSVKGPTMHLIKITMMYILSTLS----------------------PNDYFFGVY--FNN 277

  Fly   388 HKEEIISFINSLSRAQAFTNHSLGFEYSFELLHRLQQSGMINTAEQ-----PVEF-VYITRGLLT 446
            |...|||..|........:|..:.||          :.||:...:|     |::| :.:.||.|.
 Worm   278 HFNPIISCANRTFMPATTSNKKVFFE----------ELGMLEEKDQAHFATPLKFSLDVLRGNLD 332

  Fly   447 NLSDAMAVLRVVADGQRRLRAPVIINTCAV------VLDEK---------RIM-----YEKQFL- 490
            :.....|..|  ::|.:.|    ||.|..|      :|||:         ||.     |....|
 Worm   333 SNQSLFADYR--SEGHKLL----IIFTDGVDEWPHQILDEEFQTRNSELIRIFGFSMGYGTSLLP 391

  Fly   491 --NDVASQNYTKY-EID-VASWWPSGQEASELVGRFYVLSKMHAETSLPQTSSRIFGPLFQERYL 551
              ..:|.:::..| ||| :....|..:....      |||::..: .|..|::....|.:.:.|:
 Worm   392 LQQYMACKSHGGYSEIDSIMDVKPQSRTIQN------VLSQVRGD-ELKGTNAEKREPSWTQLYM 449

  Fly   552 SD-------TLEVHPPVVDADSGDVLVSITHAVPPYGVVGVNLYLSDLLEDLLNYPSTTSSAKQG 609
            ..       ||.:  |::.::.     .|.......|||.:::.:.:..:.|     .|||.:.
 Worm   450 ETQGTGPIVTLSL--PILTSEQ-----RIWRDQKLAGVVAIDISIKEFTKHL-----PTSSEQM- 501

  Fly   610 LGYAFLLDRSTGNTLAHPAFPRP-----LIQRETSYP-----------VNIAYLENATDFSSHIR 658
              |.:::| :.|..:.||....|     .::|...|.           :.:.|     .||....
 Worm   502 --YGYIVD-NNGMLIYHPQLQIPKTEVHCVRRSACYDAQQVKQKAGSGLRVHY-----GFSDERV 558

  Fly   659 DRLLREESGNVTTDVY-----------VGRQRLQRTYYWQSVLGFYVLCLVSSGGDTLRNVSSTQ 712
            .||:.......|.|:|           :.|:...:|.|.:::                  ..:::
 Worm   559 YRLVGLIDSIPTLDMYDLEGDSTAIRDLRRRITTKTCYEEAI------------------KDNSK 605

  Fly   713 RY---NLKDT------VSNYE--PGYYGESMDLL-----------YHRLDLNQGGSAPPKTCRY- 754
            .|   ::||:      |:|.:  ..||.:|:..|           |.|.|:.|.     |...|
 Worm   606 EYHCSHIKDSPFTLVIVNNIQLKTVYYDDSVQELGLTDNKLVTFFYPRRDVCQW-----KLDEYA 665

  Fly   755 ----FR--------QVATMDAPTLFLSAAAFESPFGFLHNNRPRTQLRHVESIMAYLRDSSGLLA 807
                ||        ::...|...|   ..||....|....:.|::.:.|...::|...:::.:
 Worm   666 AHDRFRVWSDISEKEICAQDDMRL---PRAFTKGLGSWTQSWPKSDIEHTTCLLAQYPENASV-- 725

  Fly   808 NMGLRPSIRHEVGVLYQAMQQLRRRHQDARGSLRSHVIRRYIASVSGVLQLYPGCLLSSSYD-PT 871
                                              .|.:..::.:.|.:...||.|   ||:| ..
 Worm   726 ----------------------------------PHYVNSFVHTRSKLTAFYPTC---SSHDMKA 753

  Fly   872 RRPWFRQAIAQPGKIVSTAPYLDAGGAGYIITIAHTIFEGKAHALHSAQQDRPVAVVALDVPYAF 936
            ....|.:.|    |:.....::........:.|..||.:         ..:..:|||.......|
 Worm   754 VNKKFDEEI----KLTDNNDFVQFSMRSESLLIYRTIAD---------YDNNRLAVVGTQWKENF 805

  Fly   937 ---YYRLILEGTP---ICQLPHIKCLLFEHEGYLLAHPSMLQPATLTKNQRRPHEHLTHKESYLA 995
               |:.......|   ||:..  :|.:....|:::|..:...||.|.|...:..|.|........
 Worm   806 FDQYFDNFTRQNPDWKICRKQ--ECSIITRNGHVIASSAHRAPAHLAKFDPQLFESLVKVNLVST 868

  Fly   996 NDMLN-----HGQLVRKLGCASYQNRTLQRYYA---FNTSLSSILGNVVHGERTKYAIALIRGSN 1052
            |....     ..:.|.....|:..:.::.||:.   |..:.:|...|::..     |:.|:...
 Worm   869 NSWTEVQSECKAKRVAPWSSAAPGSSSILRYFVTSIFKLAKTSFWRNLLES-----ALTLVDAQ- 927

  Fly  1053 LFAAVLNSSCDGGAFCPCSTIDREC----------LNCKRMDQTDCECPCECPMVGDSSSPSSLM 1107
              .::..::|   .|......:| |          ||..:..|......|
 Worm   928 --PSMTGNTC---TFQKIKPFER-CFMKFFHYRMTLNITKQLQLTGMSTC--------------- 971

  Fly  1108 YFANYTRQFPYCPPPSEHFIALPPTTQLLSTLPNCPGSAGICETYSTQR----ECLGVMGCEWCQ 1168
              :.|.:.:|           :|.||..|......      |..|..:|    |...:..|
 Worm   972 --SRYAKLYP-----------VPHTTLSLIIADRA------CSQYRPKRIFESEPRKLEKC---- 1013

  Fly  1169 LDV---------DG-NSFSTSFCSSQASCFNGVLASLTPYGELDEMELLAAHNPQREQHAYSAFG 1223
             ||         |. |.:.....:....|.|.|:                       .||.|.|
 Worm  1014 -DVVHSHARRRPDALNDWKIDLQNKHVDCINDVM-----------------------HHAKSYF- 1053

  Fly  1224 PLGGAIVVLVMVIGFAIY 1241
                :||:|:::..|.|:
 Worm  1054 ----SIVLLILISTFRIF 1067

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16868	NP_611469.1	vWFA	308..>426	CDD:294047	23/118 (19%)
		Cache_1	559..627	CDD:280839	12/67 (18%)
tag-180	NP_001022363.1	VWA_N	<106..201	CDD:369855	20/149 (13%)
		vWA_VGCC_like	220..411	CDD:238740	51/230 (22%)
		dCache_1	<430..>517	CDD:376917	19/103 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910