DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mpcp1 and C33F10.12

DIOPT Version :9

Sequence 1:	NP_001286628.1	Gene:	Mpcp1 / 37297	FlyBaseID:	FBgn0034497	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_494870.1	Gene:	C33F10.12 / 183168	WormBaseID:	WBGene00016358	Length:	392	Species:	Caenorhabditis elegans

Alignment Length:	372	Identity:	219/372 - (58%)
Similarity:	269/372 - (72%)	Gaps:	28/372 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFKSLFDAAQNSTFKSPFTSVNCQSATPTSAPTSTAVVTPTLKDVAPRQLTRNHNIAAAAVAEGD 65
            :|..:|||||.:....|            |||:                :.|....::||.:...
Worm     3 LFHDVFDAAQKNGIVIP------------SAPS----------------VVRTAKCSSAATSVAA 39

  Fly    66 SCEFGSNHYFLLCGLGGIISCGSTHTMVVPLDLVKCRLQVDPAKYKSVFTGFRISLAEEGVRGLA 130
            ..||||:.::.:|.|||.:|||.||..:.|||:||||:||:..||.|:..||::::||:||||||
Worm    40 PIEFGSSQFYAMCALGGSLSCGLTHFAITPLDIVKCRIQVNKEKYGSMVQGFKVTIAEDGVRGLA 104

  Fly   131 KGWAPTFIGYSMQGLCKFGLYEVFKKVYGDAIGEENAFLYRTGLYLAASASAEFFADIALAPMEA 195
            :||||||||||.|||.|||.|||||.:|..|:|||||:::||.:||||||||||||||.||||||
Worm   105 RGWAPTFIGYSAQGLGKFGFYEVFKNIYSSALGEENAYIWRTSIYLAASASAEFFADIFLAPMEA 169

  Fly   196 AKVKIQTTPGFAKTLREALPKMTAQEGVTAFYKGLVPLWMRQIPYTMMKFACFERTLELLYKYVV 260
            .||::||:|....|||...|.:..|||:|.|:|||.|||.||||||||||.|||:|:||||:|||
Worm   170 VKVRMQTSPTAPTTLRACAPMIYKQEGLTGFFKGLPPLWTRQIPYTMMKFTCFEKTVELLYQYVV 234

  Fly   261 PKPRADCTKGEQLVVTFAAGYIAGVFCAIVSHPADTVVSKLNQAKGASALDVAKQLGWSGLWGGL 325
            |||||.|:|.|||.|||.||||||||||:||||.|.:||||||...||...:.||||:.||||||
Worm   235 PKPRAQCSKSEQLAVTFTAGYIAGVFCAVVSHPPDVLVSKLNQDSNASVGSLVKQLGFKGLWGGL 299

  Fly   326 VPRIVMIGTLTAAQWFIYDAVKVFLRMPRPPPPEMPESLKKKLGVTG 372
            .|||:|:|||||.||||||:.||.:.:||||||.||||||||||:.|
Worm   300 GPRIIMVGTLTALQWFIYDSFKVAMNLPRPPPPRMPESLKKKLGIPG 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mpcp1	NP_001286628.1	Mito_carr	71..160	CDD:278578	54/88 (61%)
		Mito_carr	<188..258	CDD:278578	45/69 (65%)
		Mito_carr	273..350	CDD:278578	54/76 (71%)
C33F10.12	NP_494870.1	Mito_carr	52..132	CDD:278578	52/79 (66%)
		PTZ00169	54..324	CDD:240302	184/269 (68%)
		Mito_carr	<162..232	CDD:278578	45/69 (65%)
		Mito_carr	247..321	CDD:278578	52/73 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	128	1.000	Domainoid score	I3297
eggNOG	1	0.900	-	-		E1_KOG0767
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37649
Inparanoid	1	1.050	468	1.000	Inparanoid score	I844
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55239
OrthoDB	1	1.010	-	-		D423866at33208
OrthoFinder	1	1.000	-	-		FOG0001887
OrthoInspector	1	1.000	-	-		mtm4731
orthoMCL	1	0.900	-	-		OOG6_101022
Panther	1	1.100	-	-	O	PTHR45671
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1083
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840