Protein Alignment CG9143 and pit

DIOPT Version :10

• Sequence 1: NP_611467.1
• Gene: CG9143 / 37296
• FlyBaseID: FBgn0287774
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_524446.3
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Alignment Length: 769
• Identity: 193/769 - (25%)
• Similarity: 310/769 - (40%)
• Gaps: 222/769 - (28%)

  Fly    78 RERKLKKK--KRKVSKGDEEESSESSSESESEDEVAVAARTSKK-ARLAERHAQKMQ-------- 131
            ||:.|.||  ||:..|.:..:...:.:..:.|.......:.||| .:|:::|..|.:
  Fly     4 REKLLMKKIVKREKMKKELSQKKGNKNAQKQEPPKQNGNKPSKKPEKLSKKHVAKDEDDDLEEDF 68

  Fly   132 ---KLREKREKRKELRKQKKSKGKENDNSEESSDEHAADRFALLRPPPSDDEEEVVKAEDSADQQ 193
               .|.:|:::::..:||:......:..|::...|..||..:.|......|||:|....:..|||
  Fly    69 QEAPLPKKKQQKQPPKKQQIQVANSDSESDDDEQEDEADEDSDLDEVAEVDEEDVDSGSEDDDQQ 133

  Fly   194 ESTDEEAP------ELVP-------------------------ISTGEAEDMSAWNGLG-VPASI 226
            |..|||.|      :|:|                         :...:::|.|..:..| |..:.
  Fly   134 EDEDEEEPVPAKKTKLLPNKSKAQNGKPAKDDEPFTVESSLAALDYRDSDDRSFASLKGAVSEAT 198

  Fly   227 LRALGEQGFKTPTQIQALTLPAAIHGKKDILGAAETGSGKTLAFGIPMLAGIMELK--QRNIRSG 289
            |||:.|.||...|:||:.:|...:.| :|::|||:|||||||||.||.:..|.:|:  .|| .:|
  Fly   199 LRAIKEMGFTEMTEIQSKSLTPLLKG-RDLVGAAQTGSGKTLAFLIPAVELINKLRFMPRN-GTG 261

  Fly   290 IRKAPKVKGQQPEPAADEHELTPPPEELDHVSGASDEESDAEEQAQRVQTPLYGLVLTPTRELAV 354
            :                                                     ::::|||||::
  Fly   262 V-----------------------------------------------------IIISPTRELSM 273

  Fly   355 Q---VKNHLVAAAKYTGIRVAAIFGGLAVAKQERVLRQCPDIVVATPGRLWELYAQGNRHLGKIE 416
            |   |...|:|...:|   ...:.||.....:...|.:..:|:|||||||.:       ||....
  Fly   274 QTFGVLKELMAHHHHT---YGLVMGGSNRQVESEKLGKGINILVATPGRLLD-------HLQNSP 328

  Fly   417 DVSF-----LVIDETDRMVEKGHFEELRSLLKVLNSDEQKKHQRQNFVYSATLTLVHDLPDHMQK 476
            |..:     |:|||.||::|.|..|||:.::.:|      ..:||..::|||.|
  Fly   329 DFLYKNLQCLIIDEVDRILEIGFEEELKQIINLL------PKRRQTMLFSATQT----------- 376

  Fly   477 RNVGKRPKFVKQTVDQKIESLIEELGISQPKIVDITSSQQTAQT--LTESRLLCPIDHKDYHLYY 539
                           .:||:|.:....|:|..|.:..:|.||..  |.:..::||.:.:...|:.
  Fly   377 ---------------ARIEALSKLALKSEPIYVGVHDNQDTATVDGLEQGYIVCPSEKRLLVLFT 426

  Fly   540 FIQRH-PGRTIVFCNSIDCVKRLATLFGLLDCNPLPLHANMIQKQRLKNLERFRDSPTGLLIATD 603
            |:::: ..:.:||.:|...||....||..:|.....:|....|.:|.....:|.::.:|:|:.||
  Fly   427 FLKKNRKKKVMVFFSSCMSVKYHHELFNYIDLPVTSIHGKQKQTKRTTTFFQFCNAESGILLCTD 491

  Fly   604 VAARGLDIPNVEHVIHYQVPRTSENYVHRSGRTAR-ANKHGITVMFMEPGEV------------- 654
            |||||||||.|:.::.|..|.....|:||.||||| :...|..::.|.|.|:
  Fly   492 VAARGLDIPQVDWIVQYDPPDDPREYIHRVGRTARGSGTSGHALLLMRPEELGFLRYLKAAKVPL 556

  Fly   655 -----------------------------------KSYVKLY-----KTLERTEDLPLFPILERF 679
                                               ||||:.|     |.:.....|.|..:.:.|
  Fly   557 NEFEFSWQKIADIQLQLEKLIAKNYFLNQSAKEAFKSYVRAYDSHQLKQIFNVNTLDLQAVAKSF 621

  Fly   680 MGAVRERVNLARDLDKEELKLKRVQSER-GWMKKHAEEMDMIIDGYNDESGSDQ 732
            ...|...|:|.....|.|...|||.... |:.||           .|:.|.|.|
  Fly   622 GFLVPPVVDLKVGAAKRERPEKRVGGGGFGFYKK-----------MNEGSASKQ 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9143	NP_611467.1	DEADc_DDX24	226..510	CDD:350704	78/293 (27%)
		SF2_C_DEAD	521..648	CDD:350174	42/128 (33%)
pit	NP_524446.3	DEADc_DDX18	198..395	CDD:350700	78/293 (27%)
		SF2_C_DEAD	408..537	CDD:350174	42/128 (33%)
		DUF4217	570..627	CDD:464056	10/56 (18%)