DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9143 and abs

DIOPT Version :9

Sequence 1:	NP_611467.1	Gene:	CG9143 / 37296	FlyBaseID:	FBgn0034496	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	NP_524220.1	Gene:	abs / 40530	FlyBaseID:	FBgn0015331	Length:	619	Species:	Drosophila melanogaster

Alignment Length:	690	Identity:	177/690 - (25%)
Similarity:	291/690 - (42%)	Gaps:	174/690 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 PDRERK---LKKKKRKVSKGDEEESSESSSESESEDEVAVAARTSKKARLAERHAQKMQ-KLREK 136
            |.:|||   :.|..|.|....|....:||||:|:||:       |:.|...|...:|.. .|.::
  Fly    29 PVKERKKQHMIKLGRIVQLVSETAQPKSSSENENEDD-------SQGAHDVETWGRKYNISLLDQ 86

  Fly   137 REKRKELRKQKKSKGKEND-NSEESSDEHAADRFALL-------------------RPP-----P 176
            ..:.|::.:.||....|.. ..||...|..|.:.||:                   :||     .
  Fly    87 HTELKKIAEAKKLSAVEKQLREEEKIMESIAQQKALMGVAELAKGIQYEQPIKTAWKPPRYIREM 151

  Fly   177 SDDEEEVVKAEDSADQQESTDEEAPELVPISTGEAEDMSAWNGLGVPASILRALGEQGFKTPTQI 241
            |::|.|.|:.|    .:...:.|.|         :..:.::..:..|..||..|..:|.|.||.|
  Fly   152 SEEEREAVRHE----LRILVEGETP---------SPPIRSFREMKFPKGILNGLAAKGIKNPTPI 203

  Fly   242 QALTLPAAIHGKKDILGAAETGSGKTLAFGIPMLAGIMELKQRNIRSGIRKAPKVKGQQPEPAAD 306
            |...||..:.| :|::|.|.|||||||.|.:|::...:|                         .
  Fly   204 QVQGLPTVLAG-RDLIGIAFTGSGKTLVFVLPVIMFALE-------------------------Q 242

  Fly   307 EHELTPPPEELDHVSGASDEESDAEEQAQRVQTPLYGLVLTPTRELAVQV-------KNHLVAAA 364
            |:.|   |.|                   |.:.| |||::.|:||||.|.       ..||.|..
  Fly   243 EYSL---PFE-------------------RNEGP-YGLIICPSRELAKQTHEIIQHYSKHLQACG 284

  Fly   365 KYTGIRVAAIFGGLAVAKQERVLRQCPDIVVATPGRLWELYAQGNRHLGKIEDVSFLVIDETDRM 429
             ...||.....|||.|::...|:.:...|||||||||.::.   ::.:..::...:|.:||.|||
  Fly   285 -MPEIRSCLAMGGLPVSEALDVISRGVHIVVATPGRLMDML---DKKILTLDMCRYLCMDEADRM 345

  Fly   430 VEKGHFEELRSLLKVLNSDEQKKHQRQNFVYSATLTLVHDLPDHMQKRNVGKRPKFVKQTVDQKI 494
            ::.|..|::|::....      |.|||..::|||      :|..:|        .|.:..:.:.:
  Fly   346 IDMGFEEDVRTIFSFF------KGQRQTLLFSAT------MPKKIQ--------NFARSALVKPV 390

  Fly   495 ESLIEELGISQPKIVDITSSQQTAQTLTESRLLCPIDHKDYHLYYFIQRHPGRTIVFC---NSID 556
            ...:...|.:...:     :||......|::::..:|        .:|:.....::|.   ..:|
  Fly   391 TINVGRAGAASMNV-----TQQVEYVKQEAKVVYLLD--------CLQKTAPPVLIFAEKKQDVD 442

  Fly   557 CVKRLATLFGLLDCNPLPLHANMIQKQRLKNLERFRDSPTGLLIATDVAARGLDIPNVEHVIHYQ 621
            |:.....|.|:   ..:.:|....|::|.:.::.:|.....:|:|||||::|||.|||:|||:|.
  Fly   443 CIHEYLLLKGV---EAVAIHGGKDQEERSRAVDAYRVGKKDVLVATDVASKGLDFPNVQHVINYD 504

  Fly   622 VPRTSENYVHRSGRTARANKHGITVMFMEPGEVKSYVKLYKTL--ERTEDLP-----LFPILER- 678
            :|...||||||.|||.|:|..|:....:.....:|.:...|.|  |..:::|     |.|..|.
  Fly   505 MPDDIENYVHRIGRTGRSNTKGLATTLINKTTEQSVLLDLKHLLIEGKQEVPDFLDELAPETEHQ 569

  Fly   679 -----------FMGAVRERVNLARDLDKEELKLKRVQSER 707
                       :.|.:..|:.       |..||:.||:::
  Fly   570 HLDLGDSHGCTYCGGLGHRIT-------ECPKLEAVQNKQ 602

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9143	NP_611467.1	BLVR	<125..191	CDD:283923	19/91 (21%)
		SrmB	201..747	CDD:223587	139/536 (26%)
		P-loop_NTPase	217..465	CDD:304359	76/254 (30%)
		HELICc	531..648	CDD:238034	40/119 (34%)
abs	NP_524220.1	DEADc	179..393	CDD:238167	79/286 (28%)
		DEXDc	192..397	CDD:214692	76/277 (27%)
		Helicase_C	414..523	CDD:278689	39/119 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451543
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840