Protein Alignment CG10444 and SLC5A4

DIOPT Version :9

• Sequence 1: NP_611465.2
• Gene: CG10444 / 37294
• FlyBaseID: FBgn0034494
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_016884409.1
• Gene: SLC5A4 / 6527
• HGNCID: 11039
• Length: 689
• Species: Homo sapiens
• Alignment Length: 626
• Identity: 140/626 - (22%)
• Similarity: 252/626 - (40%)
• Gaps: 129/626 - (20%)

  Fly    41 YLMADQSMTTFPVSFSLMASFMSAISLMGVSNESYEFGTIFCVINIAYVLSTPIAAYFFLPVFYR 105
            :.:|.:.|..:|:..||.||.:.:...:|::......|...........:...|..:.|:|::.:
Human    88 FFLAGRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIK 152

  Fly   106 MRTTSVYEYLERRFGQATRLS---ASLAFTVQMVLYMGIALYAPALALEAVTGIHRSMAIVVIGL 167
            ....::.|||::||| ..||.   :.|:..:.:||.:...::|.|:.::...|:...:||.::..
Human   153 SGVMTMPEYLKKRFG-GERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLA 216

  Fly   168 VCTFYSTLGGLKAVLITDVFQSFLMFAAIYAVIAVSAIKAGGFAAIWD------VAVERG----- 221
            :...|:|.|||.:|:.||..|:.:|....:.::..:..:.||:.:..:      .:|..|
Human   217 MTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTI 281

  Fly   222 -------RVNFIEFSLDPTVRHTWWSLIIGGM-VTYLSLYGVNQTQVQRLLSVRNLKSAQSA--L 276
                   |.:......|.......|..||.|| :|.|..:..||..|||.|..:::...::|  :
Human   282 SASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIM 346

  Fly   277 WWNLPILGMLSFSTIFSGLSIFYYYRD---------CDPLLKGRIDKRDQIMPLFALETMGQYPG 332
            ...|.:|.|  |..:..|:.....|.|         |.......:...:...|...||.|.|  |
Human   347 CAYLKLLPM--FLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQ--G 407

  Fly   333 LCGLFVSGIFSASLSTISSAVTSLSAV-TLEDYLKPLYKAIFKRTLIDSKSTMPTKIVACIFGLL 396
            |.||.:|.:.::.:|:::|...|.|.: |::.|.|...:|..|..||..:          ||.||
Human   408 LRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGR----------IFVLL 462

  Fly   397 CIGLAFV------AGSMGGVLQASLTIFGVVGGPLLAIFTLGVCTTRSNQRGVLLGFLVSLIVSF 455
            ...::.|      ....|.::..:.:|...:|.|:.|:|.|.:...|.|::|...|.:|.|.
Human   463 LTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLA--- 524

  Fly   456 WMGFGGPKPKPVT-LEFSTAGCENATAVMARAIELSSKSSGVVIEPDYFWLYRISYLWLSVIGFL 519
             ||.    .:.:| ..:.|..|            |:..:...:|       ..:.||:.|::.|.
Human   525 -MGL----IRMITEFAYGTGSC------------LAPSNCPKII-------CGVHYLYFSIVLFF 565

  Fly   520 IAVVVGYFSSIVL-----AH----CGKAENA----------------------EIYLDKSRKQLD 553
            .:::|....|::.     .|    |....|:                      |.|.:|||..|.
Human   566 GSMLVTLGISLLTKPIPDVHLYRLCWVLRNSTEERIDIDAEEKSQEETDDGVEEDYPEKSRGCLK 630

  Fly   554 --YDLF-----APMLSRRWRRHKEEQDQTAQDETLTKLTEQ 587
              ||||     .|.|:      |||::  |..:.||..:|:
Human   631 KAYDLFCGLQKGPKLT------KEEEE--ALSKKLTDTSER 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10444	NP_611465.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	118/530 (22%)
SLC5A4	XP_016884409.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810