Protein Alignment CG10444 and SLC5A3

DIOPT Version :9

• Sequence 1: NP_611465.2
• Gene: CG10444 / 37294
• FlyBaseID: FBgn0034494
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_008864.4
• Gene: SLC5A3 / 6526
• HGNCID: 11038
• Length: 718
• Species: Homo sapiens
• Alignment Length: 513
• Identity: 114/513 - (22%)
• Similarity: 212/513 - (41%)
• Gaps: 93/513 - (18%)

  Fly     7 DAWDAAVLITILVISALIGIYYRYTGGKQKTTQEYLMADQSMTTFPVSFSLMASFMSAISLMGVS 71
            |..|.|::....::...||.:..:...: .|...|.:|.:|||...:..||..|.:.:...:|::
Human     6 DTADIAIVALYFILVMCIGFFAMWKSNR-STVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLA 69

  Fly    72 NESYEFGTIFCVINIAYVLSTPIAAYFFLPVFYRMRTTSVYEYLERRFGQATRLSASLAFTVQMV 136
            ......|..........:|...:..:.|:|::.|....::.|||.:||| ..|:....| .:.::
Human    70 GSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFG-GHRIQVYFA-ALSLI 132

  Fly   137 LY----MGIALYAPALALEAVTGIHRSMAIVVIGLVCTFYSTLGGLKAVLITDVFQSFLMFAAIY 197
            ||    :.:.||:.||.::...|.:..::::::..:....:..|||.||:.||..|:.||.....
Human   133 LYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGAL 197

  Fly   198 AVIAVSAIKAGGFAAI-------------------------WDVAVERGRVNFIEFSLDPTVRHT 237
            .::.:|.::.|||..:                         .:|:.::..:..:....|..|  .
Human   198 TLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSPKKEALKMLRNPTDEDV--P 260

  Fly   238 WWSLIIGGMVTYLSLYGVNQTQVQRLLSVRNLKSAQSALWWNLPILGMLSFSTIFSG-LSIFYYY 301
            |...|:|.....:..:..:|..|||:|:.:|:..|:.              ||:.:| |.:...:
Human   261 WPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKG--------------STLMAGFLKLLPMF 311

  Fly   302 RDCDPLLKGRIDKRDQIM---PLFALETMGQ--------YP---------GLCGLFVSGIFSASL 346
            ....|.:..||...|.|.   |...:...|.        ||         ||.||.::.:.:|.:
Human   312 IIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVPVGLRGLMMAVMIAALM 376

  Fly   347 STISSAVTSLSAV-TLEDYLKPLYKAIFKRTLIDSKSTMPTKIVACIF--GLLCIGLAFV---AG 405
            |.:.|...|.|.: ||:     :||.|.|     |.|:....||..||  .::.|.:|:|   ..
Human   377 SDLDSIFNSASTIFTLD-----VYKLIRK-----SASSRELMIVGRIFVAFMVVISIAWVPIIVE 431

  Fly   406 SMGGVLQASL-TIFGVVGGPLLAIFTLGVCTTRSNQRGV----LLGFL---VSLIVSF 455
            ..||.:...: .:...:..|:.|:|.|.:...|.|::|.    :.||:   |.||::|
Human   432 MQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAVRLILAF 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10444	NP_611465.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	113/511 (22%)
SLC5A3	NP_008864.4	SLC5sbd_SMIT	9..718	CDD:271382	113/510 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810