Protein Alignment CG10444 and Slc5a4a

DIOPT Version :10

• Sequence 1: NP_611465.2
• Gene: CG10444 / 37294
• FlyBaseID: FBgn0034494
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_573447.2
• Gene: Slc5a4a / 64452
• MGIID: 1927848
• Length: 656
• Species: Mus musculus
• Alignment Length: 625
• Identity: 136/625 - (21%)
• Similarity: 269/625 - (43%)
• Gaps: 108/625 - (17%)

  Fly     7 DAWDAAVLITILVISALIGIYYRYTGGKQKTTQEYLMADQSMTTFPVSFSLMASFMSAISLMGVS 71
            :|.|.:|::...|:...:|::......: .|...:.:|.:|||.:|:..||.||.:.:...:|::
Mouse    25 NAADISVIVIYFVVVMAVGVWAMLKTNR-STVGGFFLAGRSMTWWPMGASLFASNIGSGHFVGLA 88

  Fly    72 NESYEFG---TIFCVINIAYVLSTPIAAYFFLPVFYRMRTTSVYEYLERRF-GQATRLSASLAFT 132
            ......|   |.|...:.|.:|   :..:.|:|::.:....::.|||::|| |:..::..|:.|.
Mouse    89 GTGAASGIAVTAFESHSFALLL---VLGWIFVPIYIKAGVMTMPEYLKKRFGGKRLQIYLSILFL 150

  Fly   133 -VQMVLYMGIALYAPALALEAVTGIHRSMAIVVIGLVCTFYSTLGGLKAVLITDVFQSFLMFAAI 196
             :.::|.:...:::.|:.::...|::..:||:::..:...::..|||.:|:.||..|:.:|....
Mouse   151 FICVILTISADIFSGAIFIKLALGLNLYLAILILLAITAIFTITGGLASVIYTDTVQAVIMLVGS 215

  Fly   197 YAVIAVSAIKAGGFAAIWD---------VAVERGRVNFIEFSLDPTVRH----------TWWSLI 242
            :.::..:.::.||:.:..:         |..:...:|...::..|...|          .|....
Mouse   216 FILMVFAFVEVGGYESFTEKFMNAIPSVVEGDNLTINSRCYTPQPDSFHIFRDPVTGDIPWPGTA 280

  Fly   243 IGGMVTYLSLYGVNQTQVQRLLSVRNLKSAQSA--LWWNLPILGMLSFSTIFSGLSIFYYYRD-- 303
            .|..:|.|..:.:||..|||.|..:||...::|  |...|.:|.:  |..:..|:.....|.|
Mouse   281 FGMPITALWYWCINQVIVQRCLCGKNLSHVKAACILCGYLKLLPL--FFMVMPGMISRILYTDMV 343

  Fly   304 -------CDPLLKGRIDKRDQIMPLFALETMGQYPGLCGLFVSGIFSASLSTISSAVTSLSAV-T 360
                   |.......:...:...|:..|:.|..  ||.||.:|.:.::.:|:::|...|.|.: |
Mouse   344 ACVVPSECVKHCGVDVGCTNYAYPMLVLKLMPM--GLRGLMLSVMLASLMSSLTSVFNSASTLFT 406

  Fly   361 LEDYLKPLYKAIFKRTLIDSKSTMPTKIVACIFGLLCIGLAFVAGSMGG-VLQASLTIFGVVGGP 424
            ::.|.|...||..:..||..:..:...||..|     :.:..|..|.|| ::..:..|...:|.|
Mouse   407 IDLYTKIRKKASERELLIAGRLFVSVLIVTSI-----LWVPIVEVSQGGQLVHYTEAISSYLGPP 466

  Fly   425 LLAIFTLGVCTTRSNQRGVLLGFLVSLIVSFWMGFGGPKPKPVTLEFS--TAGCENATAVMARAI 487
            :.|:|.:.|...|:|::|...|.:|.|::....         :..|||  |..|
Mouse   467 IAAVFLVAVFCKRANEQGAFWGLMVGLVMGLIR---------MIAEFSYGTGSC----------- 511

  Fly   488 ELSSKSSGVVIEPDYFWLYRISYLWLSVIGFLIAVV----VGYFSS-IVLAH----CGKAENAEI 543
             |:..|...:|       ..:.||:.::|.|.:.::    |.|.:. |...|    |....|::
Mouse   512 -LAPSSCPKII-------CGVHYLYFAIILFFVCILVILGVSYLTKPIPDVHLHRLCWALRNSK- 567

  Fly   544 YLDKSRKQLDYDLFAPMLSRRWRRHKEE---QDQTAQDET 580
                 .:::|.|          ...|||   .|:|.:|:|
Mouse   568 -----EERIDLD----------AEDKEENGADDRTEEDQT 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10444	NP_611465.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	122/565 (22%)
Slc5a4a	NP_573447.2	SLC5-6-like_sbd	27..656	CDD:444915	135/623 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	574..593		8/29 (28%)